Zobrazeno 1 - 10
of 187
pro vyhledávání: '"M M, Van den Heuvel"'
Autor:
I M A A van Roessel, J E Gorter, B Bakker, M M van den Heuvel-Eibrink, M H Lequin, J van der Lugt, L Meijer, A Y N Schouten-van Meeteren, H M van Santen
Publikováno v:
Endocrine Connections, Vol 13, Iss 10, Pp 1-9 (2024)
Objective: Children with a supratentorial midline low-grade glioma (LGG) may be at risk for impaired bone health due to hypothalamic-pituitary dysfunction, obesity, exposure to multiple treatment modalities, and/or decreased mobility. The presence of
Externí odkaz:
https://doaj.org/article/7ed742e2aa934db7a99ef62ed41a9caf
Autor:
R D Schouten, I Schouten, M M F Schuurbiers, V van der Noort, R A M Damhuis, E H F M van der Heijden, J A Burgers, N P Barlo, A S R van Lindert, K W Maas, J J G van den Brand, A A J Smit, J M W van Haarst, B van der Maat, E Schuuring, H Blaauwgeers, S M Willems, K Monkhorst, D van den Broek, M M van den Heuvel
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0290939 (2024)
IntroductionMolecular profiling of NSCLC is essential for optimising treatment decisions, but often incomplete. We assessed the efficacy of protocolised molecular profiling in the current standard-of-care (SoC) in a prospective observational study in
Externí odkaz:
https://doaj.org/article/87e38726aa1c4be1b473231f9e459023
Autor:
A. M. van Hulst, E. J. Verwaaijen, M. F. Fiocco, S. M. F. Pluijm, M. A. Grootenhuis, R. Pieters, E. L. T. van den Akker, M. M. van den Heuvel-Eibrink
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as detrimental with respe
Externí odkaz:
https://doaj.org/article/08ba3da1d9554c76bbc077b8c7062f17
Autor:
A. J. M. Meijer, F. A. Diepstraten, T. Langer, L. Broer, I. K. Domingo, E. Clemens, A. G. Uitterlinden, A. C. H. de Vries, M. van Grotel, W. P. Vermeij, R. A. Ozinga, H. Binder, J. Byrne, E. van Dulmen-den Broeder, M. L. Garrè, D. Grabow, P. Kaatsch, M. Kaiser, L. Kenborg, J. F. Winther, C. Rechnitzer, H. Hasle, T. Kepak, K. Kepakova, W. J. E. Tissing, A. L. F. van der Kooi, L. C. M. Kremer, J. Kruseova, S. M. F. Pluijm, C. E. Kuehni, H. J. H. van der Pal, R. Parfitt, C. Spix, A. Tillmanns, D. Deuster, P. Matulat, G. Calaminus, A. E. Hoetink, S. Elsner, J. Gebauer, R. Haupt, H. Lackner, C. Blattmann, S. J. C. M. M. Neggers, S. R. Rassekh, G. E. B. Wright, B. Brooks, A. P. Nagtegaal, B. I. Drögemöller, C. J. D. Ross, A. P. Bhavsar, A. G. am Zehnhoff-Dinnesen, B. C. Carleton, O. Zolk, M. M. van den Heuvel-Eibrink, the PanCareLIFE Consortium, and the CPNDS Consortium
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract In children with cancer, the heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility. Using a genome-wide association study (GWAS) approach, we identified a genetic variant in TCERG1L (rs893
Externí odkaz:
https://doaj.org/article/1a21ee1f4f0440f184693f4b2b482abf
Autor:
N. Oosterom, M. Fiocco, R. Q. H. Kloos, I. M. van der Sluis, R. Pieters, B. D. van Zelst, D. E. C. Smith, M. M. van den Heuvel-Eibrink, R. de Jonge, S. G. Heil
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background After High-Dose Methotrexate (HD-MTX), folinic acid rescue therapy (Leucovorin) is administered to reduce side effects in pediatric acute lymphoblastic leukemia (ALL) patients. Leucovorin and MTX are structural analogues, possibly
Externí odkaz:
https://doaj.org/article/adb1e98d32e34de4a97a5e539ca4d3ec
Autor:
V G Pluimakers, M van Waas, C W N Looman, M P de Maat, R de Jonge, P Delhanty, M Huisman, F U S Mattace-Raso, M M van den Heuvel-Eibrink, S J C M M Neggers
Publikováno v:
Endocrine Connections, Vol 9, Iss 7, Pp 676-686 (2020)
Purpose: Augmented survival of childhood nephroblastoma and neuroblastoma has increased long-term side effects such as metabolic syndrome (Met S). Risk stratification is difficult after abdominal radiation because waist circumferenc e underestimate
Externí odkaz:
https://doaj.org/article/96f1d7becb514a9a8937c21704424814
Autor:
W. S. M. E. Theelen, O. Krijgsman, K. Monkhorst, T. Kuilman, D. D. G. C. Peters, S. Cornelissen, M. A. Ligtenberg, S. M. Willems, J. L. G. Blaauwgeers, C. J. M. van Noesel, D. S. Peeper, M. M. van den Heuvel, K. Schulze
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background The tumor immune microenvironment is a heterogeneous entity. Gene expression analysis allows us to perform comprehensive immunoprofiling and may assist in dissecting the different components of the immune infiltrate. As gene expre
Externí odkaz:
https://doaj.org/article/debbea0e0b5047e685a2c5ef50af7bd0
Autor:
E Driehuis, N Oosterom, S G Heil, I B Muller, M Lin, S Kolders, G Jansen, R de Jonge, R Pieters, H Clevers, M M van den Heuvel-Eibrink
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0231588 (2020)
We have recently established a protocol to grow wildtype human oral mucosa organoids. These three-dimensional structures can be maintained in culture long-term, do not require immortalization, and recapitulate the multilayered composition of the epit
Externí odkaz:
https://doaj.org/article/bdaf1d17b670442ea0e22c261882a292
Autor:
E Driehuis, N Oosterom, S G Heil, I B Muller, M Lin, S Kolders, G Jansen, R de Jonge, R Pieters, H Clevers, M M van den Heuvel-Eibrink
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237488 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0231588.].
Externí odkaz:
https://doaj.org/article/253e4055409342f79bf94a1683f7b06e
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210646 (2019)
Childhood cancer patients treated with platinums often develop hearing loss and the degree is classified according to different scales globally. Our objective was to compare concordance between five well-known ototoxicity scales used for childhood ca
Externí odkaz:
https://doaj.org/article/23c096cb14d8485bb46c913e3db8b378