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Interleukin-2 Is a Potent Inhibitor of Ley dig Cell Steroidogenesis*

Autor: J H Calkins, Tu Lin, M M Sigel, H. Guo

Publikováno v: Endocrinology. 127:1234-1239

Interstitial tissue of the testis consists of Leydig cells, macrophages, lymphocytes, plasma cells, mast cells and fibroblasts. Previously we have reported that interleukin-1 (IL-1) inhibits Leydig cell androgen production. In the present study, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208300790743d7b9fa1abfcf25ade787
https://doi.org/10.1210/endo-127-3-1234

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Cholylglycine measured in serum by RIA and interleukin-1 beta determined by ELISA in differentiating viral hepatitis from chemical liver injury

Autor: G Y, Li, T, Wang, E M, Huggins, N K, Shams, J F, Davis, J H, Calkins, C A, Hornung, J M, Altekruse, M M, Sigel

Publikováno v: Journal of occupational medicine. : official publication of the Industrial Medical Association. 34(9)

Serum bile acids have been shown to serve as useful indicators of liver disease. We have confirmed these findings and added an analysis of interleukin-1 beta (IL-1 beta) profiles to further differentiate viral hepatitis from toxic liver damage associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46ef2f49ae62982852ed05e95b5d3521
https://pubmed.ncbi.nlm.nih.gov/1447600

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Interleukin-1 beta induces interleukin-1 alpha messenger ribonucleic acid expression in primary cultures of Leydig cells

Autor: D L, Wang, M L, Nagpal, J H, Calkins, W W, Chang, M M, Sigel, T, Lin

Publikováno v: Endocrinology. 129(6)

Previously, we have reported that interleukin-1 (IL-1) can modulate Leydig cell steroidogenesis. Recently, IL-1-like material has been shown to be present in the testis; however, the cellular source of this material remains unclear. In the present st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07170190f212261e8dcceba05edbbf75
https://pubmed.ncbi.nlm.nih.gov/1954872

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Comparative Ligand-Binding by Purified Nurse Shark Natural Antibodies and Anti-2,4-Dinitrophenyl Antibodies from Other Species

Autor: Edward W. Voss, Stuart Rudikoff, M. M. Sigel

Publikováno v: The Journal of Immunology. 107:12-18

A population of 19S IgM specific for the 2,4-dinitrophenyl group was purified from normal nurse shark sera by immune precipitation with high concentrations of dinitrophenylated protein antigens. Hapten-binding properties of the purified antibody were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68f8b489e9c38b81d9e03a0c43a09e0e
https://doi.org/10.4049/jimmunol.107.1.12

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