Zobrazeno 1 - 10
of 34
pro vyhledávání: '"M M, LaVail"'
Publikováno v:
Molecular Vision
Purpose Previously, several quantitative trait loci (QTL) that influence age-related retinal degeneration (ageRD) were demonstrated in a cross between the C57BL/6J-c2J and BALB/cByJ strains (B x C). In this study, as a complementary approach to ongoi
Autor:
M M, LaVail
Publikováno v:
Progress in brain research. 131
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To determine the extent to which rhodopsin mis-sorting and constitutive activation of the phototransduction cascade contribute to retinal degeneration in a transgenic rat model of retinitis pigmentosa.Retinas from transgenic rats expressing truncated
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(20)
Brain-derived neurotrophic factor (BDNF) acts through TrkB, a receptor with kinase activity, and mitigates light-induced apoptosis in adult mouse rod photoreceptors. To determine whether TrkB signaling is necessary for rod development and function, w
Publikováno v:
Investigative ophthalmologyvisual science. 40(5)
To determine whether the degenerating photoreceptors in nervous (nr/nr) and Purkinje cell degeneration (pcd/pcd) mutant mice are more susceptible to the damaging effects of constant light than those in age-matched normal mice.Beginning at two ages fo
Publikováno v:
Investigative ophthalmologyvisual science. 39(3)
Exogenous basic fibroblast growth factor (bFGF) induces bFGF gene expression in cultured rat Müller cells. To elucidate the mechanism that links exogenous bFGF to transcriptional regulation of bFGF gene expression in these cells, the authors examine
Publikováno v:
Investigative ophthalmologyvisual science. 39(3)
To investigate the induction of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) gene expression by prostaglandin E2 (PGE2) in cultured rat Müller cells and to study the mechanism of the induction.Müller cells wer
Autor:
M M, LaVail, D, Yasumura, M T, Matthes, C, Lau-Villacorta, K, Unoki, C H, Sung, R H, Steinberg
Publikováno v:
Investigative ophthalmologyvisual science. 39(3)
To examine the protective effect of a number of survival factors on degenerating photoreceptors in mutant mice with naturally occurring inherited retinal degenerations, including retinal degeneration (rd/rd), retinal degeneration slow (rds/rds), nerv
Publikováno v:
The Journal of comparative neurology. 392(1)
In the dystrophic Royal College of Surgeons (RCS) rat retina, there is a progressive loss of photoreceptors. As a result, the retinal circulation becomes apposed to the retinal pigment epithelium (RPE) and neovascular formations develop. RPE and inne
Publikováno v:
Perspectives on developmental neurobiology. 3(3)
A cardinal event in the development of all brain structures is the time at which progenitor cells leave the cell cycle and begin to differentiate. We examined cell genesis in the retina of the macaque monkey (Macaca mulatta) by labeling dividing cell