Zobrazeno 1 - 10
of 47
pro vyhledávání: '"M M, Hosey"'
Publikováno v:
Journal of Biological Chemistry. 269:1099-1105
G protein-coupled receptor kinases (GRKs) such as rhodopsin kinase and the beta-adrenergic receptor kinase (beta ARK) play an important role in agonist-specific phosphorylation and desensitization of G protein-coupled receptors. GRK5 is a recently id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e8d2b77d4965c664a7364d98d03ecf
https://doi.org/10.1016/s0021-9258(17)42226-5
https://doi.org/10.1016/s0021-9258(17)42226-5
Publikováno v:
Trends in cardiovascular medicine. 6(8)
L-type Ca channels are complex heteromultimeric proteins that play important roles in the cardiovascular system. Recent studies have revealed new insights into how the pore-forming α(1) subunits interact with accessory subunits to produce functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd11845b3147d1a64c0d6283e7957295
https://pubmed.ncbi.nlm.nih.gov/21232307
https://pubmed.ncbi.nlm.nih.gov/21232307
Autor:
A J, Chien, M M, Hosey
Publikováno v:
Journal of bioenergetics and biomembranes. 30(4)
Different post-translational modifications of Ca channel beta subunits have been identified. Recent studies have characterized the palmitoylation of the Ca channel beta2a subunit, as well as one effect of this modification on channel function. The po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6a1c340b2b2ed40df86c4223beaeadf
https://pubmed.ncbi.nlm.nih.gov/9758333
https://pubmed.ncbi.nlm.nih.gov/9758333
Publikováno v:
The Journal of biological chemistry. 273(36)
In this study, we report that palmitoylation was a critical determinant of the subcellular localization of the rat beta2a subunit of voltage-dependent calcium channels. Immunohistochemical staining of transfected cells revealed that a palmitoylation-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f81b4ff297d1ef47307638438232eb3
https://pubmed.ncbi.nlm.nih.gov/9722599
https://pubmed.ncbi.nlm.nih.gov/9722599
Publikováno v:
The Journal of biological chemistry. 272(38)
Recent studies have identified agonist-dependent phosphorylation as a critical event in the rapid uncoupling of the m2 muscarinic cholinergic receptors (mAChR) from G-proteins and sequestration of the receptors away from the cell surface. However, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8262479cc576842b5fee5b7751c9de66
https://pubmed.ncbi.nlm.nih.gov/9295310
https://pubmed.ncbi.nlm.nih.gov/9295310
The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors
Publikováno v:
Progress in brain research. 109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a1882eb3c4c85f9939f51e8220765db
https://pubmed.ncbi.nlm.nih.gov/9009704
https://pubmed.ncbi.nlm.nih.gov/9009704
Publikováno v:
Molecular pharmacology. 47(2)
Agonist-dependent phosphorylation of G protein-coupled receptors (GPRs) by G protein-coupled receptor kinases (GRKs) is proposed to be a key event initiating homologous receptor desensitization. A technical limitation hindering identification of GPRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf861bb5d32487a9dba48a131a1d50bf
https://pubmed.ncbi.nlm.nih.gov/7870029
https://pubmed.ncbi.nlm.nih.gov/7870029
Autor:
V V, Gurevich, S B, Dion, J J, Onorato, J, Ptasienski, C M, Kim, R, Sterne-Marr, M M, Hosey, J L, Benovic
Publikováno v:
The Journal of biological chemistry. 270(2)
Arrestins play an important role in quenching signal transduction initiated by G protein-coupled receptors. To explore the specificity of arrestin-receptor interaction, we have characterized the ability of various wild-type arrestins to bind to rhodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75dab098469e7c802e7086028571d62b
https://pubmed.ncbi.nlm.nih.gov/7822302
https://pubmed.ncbi.nlm.nih.gov/7822302
Publikováno v:
The Journal of biological chemistry. 269(2)
G protein-coupled receptor kinases (GRKs) such as rhodopsin kinase and the beta-adrenergic receptor kinase (beta ARK) play an important role in agonist-specific phosphorylation and desensitization of G protein-coupled receptors. GRK5 is a recently id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8419b4aee5290c83b5087badfbf604e
https://pubmed.ncbi.nlm.nih.gov/8288567
https://pubmed.ncbi.nlm.nih.gov/8288567
Publikováno v:
The Journal of biological chemistry. 268(23)
Arrestins play an important role in regulating the activity of the G protein-coupled receptors rhodopsin and the beta 2-adrenergic receptor. Recently, we described the expression and functional characterization of visual arrestin using an in vitro tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::386cc43d4d89d021ee1bd712943d0e06
https://pubmed.ncbi.nlm.nih.gov/8349577
https://pubmed.ncbi.nlm.nih.gov/8349577