Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M M, Hokom"'
Autor:
M M, Hokom, D, Lacey, O B, Kinstler, E, Choi, S, Kaufman, J, Faust, C, Rowan, E, Dwyer, J L, Nichol, T, Grasel, J, Wilson, R, Steinbrink, R, Hecht, D, Winters, T, Boone, P, Hunt
Publikováno v:
Blood. 86(12)
Megakaryocyte growth and development factor (MGDF) is a potent inducer of megakaryopoiesis in vitro and thrombopoiesis in vivo. The effects of MGDF appear to be lineage-selective, making this cytokine an ideal candidate for use in alleviating clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::524c65bb567dffe371aa790556ab777e
https://pubmed.ncbi.nlm.nih.gov/8541537
https://pubmed.ncbi.nlm.nih.gov/8541537
Autor:
P, Hunt, Y S, Li, J L, Nichol, M M, Hokom, J M, Bogenberger, S E, Swift, J D, Skrine, A C, Hornkohl, H, Lu, C, Clogston
Publikováno v:
Blood. 86(2)
The isolation and cloning of the ligand for the cytokine receptor, Mpl, have been recently described. In this report we present details of the purification of this novel cytokine (megakaryocyte growth and development factor [MGDF]) from aplastic cani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57d39574396e6beb7a61f411a414b809
https://pubmed.ncbi.nlm.nih.gov/7541666
https://pubmed.ncbi.nlm.nih.gov/7541666
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 318(3)
A recent report from this laboratory described an in vitro system in which CD34+ cells are stimulated to form mature megakaryocytes and, subsequently, cytoplasmic processes also known as pro-platelets that give rise to functional platelets. Thrombin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33bd76e32f71315efab2a31e7ea51080
https://pubmed.ncbi.nlm.nih.gov/7540495
https://pubmed.ncbi.nlm.nih.gov/7540495
Publikováno v:
Experimental hematology. 21(9)
The formation of proplatelet-like processes on megakaryocytes cultured in vitro has been shown to be inhibited by prothrombin, found residually in human serum, which is converted in culture to thrombin. This study reports that another factor found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b92a49214824d27fca9f3c9d3f4e1f8
https://pubmed.ncbi.nlm.nih.gov/8330653
https://pubmed.ncbi.nlm.nih.gov/8330653
Publikováno v:
Experimental hematology. 21(2)
The process of platelet shedding from megakaryocytes is incompletely understood, due in part to the impossibility of studying this dynamic process in vivo. Megakaryocytes in situ and in in vitro cultures display extended cytoplasmic processes constri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6db9a3522537dd16faf23bd86a29f11c
https://pubmed.ncbi.nlm.nih.gov/8425575
https://pubmed.ncbi.nlm.nih.gov/8425575
Publikováno v:
Blood. 80(4)
The mechanisms responsible for 5-fluorouracil (5FU)-induced rebound thrombocytosis are not completely understood. SI/SI(d) mice, which do not undergo rebound thrombocytosis in response to 5FU, provide a genetic approach to the study of this phenomeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dbdab06c1705d88d28c9725ee4595405
https://pubmed.ncbi.nlm.nih.gov/1379852
https://pubmed.ncbi.nlm.nih.gov/1379852
Publikováno v:
Experimental hematology. 19(8)
Developing megakaryocytes are distinguished from progenitor cells by the appearance of platelet proteins such as platelet factor 4 (PF 4). The human erythroleukemic cell line HEL can also be induced to produce PF 4 by incubation in phorbol esters. HE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::911428fe30ca6f0089399443de9ac41a
https://pubmed.ncbi.nlm.nih.gov/1868892
https://pubmed.ncbi.nlm.nih.gov/1868892
Publikováno v:
The Journal of biological chemistry. 258(8)
In normal human monocyte macrophages 125I-labeled beta-migrating very low density lipoproteins (125I-beta-VLDL), isolated from the plasma of cholesterol-fed rabbits, and 125I-human low density lipoprotein (LDL) were degraded at similar rates at prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::168be05b2aa99914cae827996a6370ef
https://pubmed.ncbi.nlm.nih.gov/6300118
https://pubmed.ncbi.nlm.nih.gov/6300118
Publikováno v:
The Journal of biological chemistry. 257(23)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef8211fb3d5366b5cab65509f4a9f2ee
https://pubmed.ncbi.nlm.nih.gov/6292220
https://pubmed.ncbi.nlm.nih.gov/6292220