Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M M, Condron"'
Publikováno v:
Journal of molecular biology. 312(5)
Amyloid beta-protein (Abeta) assembly into toxic oligomeric and fibrillar structures is a seminal event in Alzheimer's disease, therefore blocking this process could have significant therapeutic benefit. A rigorous mechanistic understanding of Abeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e72e3bcd4d017ecb8d5e66286e8a4518
https://pubmed.ncbi.nlm.nih.gov/11580253
https://pubmed.ncbi.nlm.nih.gov/11580253
Autor:
D M, Walsh, D M, Hartley, Y, Kusumoto, Y, Fezoui, M M, Condron, A, Lomakin, G B, Benedek, D J, Selkoe, D B, Teplow
Publikováno v:
The Journal of biological chemistry. 274(36)
Alzheimer's disease is characterized by extensive cerebral amyloid deposition. Amyloid deposits associated with damaged neuropil and blood vessels contain abundant fibrils formed by the amyloid beta-protein (Abeta). Fibrils, both in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::335b2e9e7bc9b07bcdbd6ef6a51c4a5b
https://pubmed.ncbi.nlm.nih.gov/10464339
https://pubmed.ncbi.nlm.nih.gov/10464339
Publikováno v:
The Journal of biological chemistry. 272(35)
Fibrillogenesis of the amyloid beta-protein (Abeta) is a seminal pathogenetic event in Alzheimer's disease. Inhibiting fibrillogenesis is thus one approach toward disease therapy. Rational design of fibrillogenesis inhibitors requires elucidation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aae78f7005f155653095b87caa4e4685
https://pubmed.ncbi.nlm.nih.gov/9268388
https://pubmed.ncbi.nlm.nih.gov/9268388
Autor:
Bobik A; Baker Medical Research Institute and Alfred Hospital, Melbourne, Victoria, Australia. alex.bobik@baker.edu.au, Agrotis A, Kanellakis P, Dilley R, Krushinsky A, Smirnov V, Tararak E, Condron M, Kostolias G
Publikováno v:
Circulation [Circulation] 1999 Jun 08; Vol. 99 (22), pp. 2883-91.