Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M M, Civan"'
Autor:
J.C. Fleischhauer, W. Daniel Stamer, M. M. Civan, Richard A. Stone, Mike O. Karl, Kim Peterson-Yantorno, Claire H. Mitchell
Publikováno v:
American Journal of Physiology-Cell Physiology. 288:C784-C794
Intraocular pressure is directly dependent on aqueous humor flow into, and resistance to flow out of, the eye. Adenosine has complex effects on intraocular pressure. Stimulation of A1and A2Aadenosine receptors changes intraocular pressure oppositely,
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C1658-C1662
Cells possess receptors for multiple different peptides that regulate a wide spectrum of biological processes. Although examples of homologous and heterologous downregulation have been reported, relatively little is known about the interaction betwee
Autor:
M. M. Civan, Cw W. Do
Publikováno v:
Acta physiologica (Oxford, England). 187(1-2)
Aqueous humour is secreted by the ciliary epithelium comprising pigmented and non-pigmented cell layers facing the stroma and aqueous humour respectively. Net chloride secretion likely limits the rate of aqueous humour formation and proceeds in three
Publikováno v:
British journal of pharmacology. 134(2)
Despite the potential importance of the mouse in studying the pharmacology of aqueous dynamics, measurement of intraocular pressure (IOP) in its very small eye has been problematic. Utilizing a novel servo-null electrophysiologic approach recently ap
Publikováno v:
Investigative ophthalmologyvisual science. 42(8)
To develop a reliable technique for measuring intraocular pressure (IOP) in the mouse.An electrophysiologic approach-the servo-null micropipette system (SNMS)-for measuring hydrostatic pressure was adapted for the mouse eye. Fine-tipped (5 microm in
Publikováno v:
Investigative ophthalmologyvisual science. 39(9)
To determine whether the Na+-K+-2Cl- symport or the parallel Na+/H+ and Cl-/HCO3- antiports provide the dominant pathway for NaCl uptake into the ciliary epithelium. Both pathways are known to support NaCl entry from the stroma into the pigmented cil
Autor:
Timothy John Claud Jacob, M. M. Civan
Publikováno v:
The American journal of physiology. 271(3 Pt 1)
The aqueous humor is secreted by the ciliary epithelium, a bilayered syncytial epithelium comprising a pigmented (PE) cell layer abutting the stroma and a nonpigmented (NPE) cell layer facing the aqueous phase. As in other epithelia, secretion depend
Publikováno v:
The American journal of physiology. 268(3 Pt 1)
Swelling activates and protein kinase C (PKC) downregulates Cl- channels in cultured nonpigmented ciliary epithelial (NPE) cells. We now report that the PKC inhibitor staurosporine upregulates whole cell Cl- currents isosmotically. The kinetics and c
Publikováno v:
Investigative ophthalmologyvisual science. 35(6)
The authors identify the signaling pathways for the regulatory volume decrease (RVD) of nonpigmented ciliary epithelial (NPE) cells. The RVD is a regulatory response triggered by swelling and reflecting KCl release by NPE cells.The cell volumes of hu
Publikováno v:
Investigative ophthalmologyvisual science. 32(6)
Transmembrane electrical measurements were performed on the isolated rabbit iris-ciliary body (I-CB) to study the direct effects of halogenated inhalation anesthetic agents on the ciliary epithelium. Addition of either halothane, enflurane, or isoflu