Zobrazeno 1 - 10
of 75
pro vyhledávání: '"M Loyevsky"'
Autor:
Abraham Shanzer, Zvi Ioav Cabantchik, Abraham M. Konijn, M Loyevsky, Hava Glickstein, William Breuer
Publikováno v:
Blood. 87:4871-4878
Iron chelators of the hydroxamate class arrest in vitro proliferation of malaria parasites end of mammalian cells. The factors determining the biological activity of the chelators have classically been attributed to the chelators' capacity for bindin
Publikováno v:
British journal of haematology. 115(4)
We tested in vitro the antimalarial properties of ICL670A, a newly developed iron chelator for the long-term oral treatment of iron overload. Ring-stage synchronized cultures of Plasmodium falciparum cultured in human erythrocytes were exposed to dif
Publikováno v:
Clinical chemistry. 45(12)
Serum transferrin receptor (sTfR) concentrations are increased in iron deficiency. We wished to examine whether they are decreased in the presence of potential iron-loading conditions, as reflected by increased transferrin saturation (TS) on a single
Autor:
G, Weiss, F, Umlauft, M, Urbanek, M, Herold, M, Loyevsky, M, Lovevsky, F, Offner, V R, Gordeuk
Publikováno v:
The Journal of infectious diseases. 180(5)
We studied the associations of macrophage activity, T-helper cell types 1 and 2 (Th-1/Th-2) responses, and iron status in 55 patients with hepatitis C virus (HCV)-related liver disease and 28 control patients with noninfectious liver disease. Serum c
Autor:
Innocent T. Gangaidzo, Thokozile Saungweme, Z. A. R. Gomo, E. G. Enquist, Hlosukwazi Khumalo, Victor Moyo, Tracey A. Rouault, Victor R. Gordeuk, T. La Vaute, Robert Stearman, R. M. Charakupa, M. Loyevsky
Publikováno v:
Gut. 45(2)
BACKGROUNDIn a previously described model, heterozygotes for an African iron loading locus develop iron overload only when dietary iron is high, but homozygotes may do so with normal dietary iron. If an iron loading gene is common, then homozygotes w
Publikováno v:
Pharmacologytherapeutics. 81(1)
Malaria is one of the major global health problems, and an urgent need for the development of new antimalarial agents faces the scientific community. A considerable number of iron(III) chelators, designed for purposes other than treating malaria, hav
Publikováno v:
Blood. 87(11)
Iron chelators of the hydroxamate class arrest in vitro proliferation of malaria parasites end of mammalian cells. The factors determining the biological activity of the chelators have classically been attributed to the chelators' capacity for bindin
Autor:
M, Loyevsky, Z I, Cabantchik
Publikováno v:
Molecular pharmacology. 45(3)
The antimalarial action and intracellular distribution of the hydrophilic agents phloridzin (PHL) (a bioflavonoid glycoside) and desferrioxamine (DFO) (an iron chelator) were studied in cultures of Plasmodium falciparum-infected human erythrocytes. W
Publikováno v:
Advances in experimental medicine and biology. 356
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461360902
All organisms need to acquire iron in a bioavailable form and integrate it into biologically active molecules1. Microorganisms and plants have developed elaborate mechanisms for the synthesis, secretion and uptake of siderophores whose task is to seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d5267f604e198d2e1455e97f818527e
https://doi.org/10.1007/978-1-4615-2554-7_40
https://doi.org/10.1007/978-1-4615-2554-7_40