Zobrazeno 1 - 10
of 15
pro vyhledávání: '"M Louise, Tierney"'
Autor:
Wenming, Xu, Ke, Wang, Yan, Chen, Xiao Tong, Liang, Mei Kuen, Yu, Huanxun, Yue, M Louise, Tierney
Publikováno v:
Reproduction, fertility, and development. 29(10)
The mechanism underlying the non-genomic action of progesterone in sperm functions and related Ca
Autor:
Jane R. Hanrahan, M. Louise Tierney, Nasiara Karim, Graham A.R. Johnston, Navnath Gavande, Mary Chebib, John Curmi
Publikováno v:
British Journal of Pharmacology. 165:880-896
Background and purpose Flavonoids are known to have anxiolytic and sedative effects mediated via actions on ionotropic GABA receptors. We sought to investigate this further. Experimental approach We evaluated the effects of 2'-methoxy-6-methylflavone
Autor:
Tien Luu, Richard W. Olsen, Andrea B. Everitt, M. Louise Tierney, Bryndis Birnir, Peter W. Gage, Brett A. Cromer
Publikováno v:
Journal of Biological Chemistry. 279:21701-21706
High conductance gamma-aminobutyric acid type A (GABA(A)) channels (>40 picosiemens (pS)) have been reported in some studies on GABA(A) channels in situ but not in others, whereas recombinant GABA(A) channels do not appear to display conductances abo
Publikováno v:
Reproduction, Fertility and Development. 29:2060
The mechanism underlying the non-genomic action of progesterone in sperm functions and related Ca2+ mobilisation remains elusive. Herein we report the expression of gamma-aminobutyric acid type A receptor delta subunit (GABRD) in human and rodent spe
Publikováno v:
Biochemical Journal. 356:589-594
The sulphate transporter SHST1, from Stylosanthes hamata, features three tightly coupled transmembrane helices which include proline residues that are conserved in most related transporters. We used site-directed mutagenesis and expression of the mut
Autor:
M. Louise Tierney, Derek R. Laver, Peter W. Gage, John Curmi, Victoria A. L. Seymour, Andrea B. Everitt
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(12)
Native GABAA channels display a single-channel conductance ranging between ∼10 and 90 pS. Diazepam increases the conductance of some of these native channels but never those of recombinant receptors, unless they are coexpressed with GABARAP. This t
Autor:
Elissa L Sutcliffe, M. Louise Tierney, Danny Rangasamy, Sudha Rao, David J. Tremethick, Ian A. Parish, Torsten Juelich, Yi Qing He, Christopher R. Parish, Peter J. Milburn
Publikováno v:
Molecular and cellular biology. 29(7)
Changes in chromatin composition are often a prerequisite for gene induction. Nonallelic histone variants have recently emerged as key players in transcriptional control and chromatin modulation. While the changes in chromatin accessibility and histo
Publikováno v:
The Journal of membrane biology. 227(3)
Hippocampal pyramidal neurons potentially express multiple subtypes of GABA(A) receptors at extrasynaptic locations that could therefore respond to different drugs. We activated extrasynaptic GABA(A) receptors in cultured rat hippocampal pyramidal ne
Publikováno v:
The international journal of biochemistrycell biology. 40(11)
The SulP family (including the SLC26 family) is a diverse family of anion transporters found in all domains of life, with different members transporting different anions. We used sequence and bioinformatics analysis of helices 1 and 2 of SulP family
Publikováno v:
The international journal of biochemistrycell biology. 40(5)
Ligand-gated ion channels respond to specific neurotransmitters by transiently opening an integral membrane ion-selective pore, allowing ions to move down their electrochemical gradient. A distinguishing feature of all members of the ligand-gated ion