Zobrazeno 1 - 10
of 1 050
pro vyhledávání: '"M Lluch"'
Publikováno v:
ACS Omega, Vol 9, Iss 40, Pp 41968-41977 (2024)
Externí odkaz:
https://doaj.org/article/479cfb1ff0724eb380ef7dd78f8102eb
Autor:
Alexander Zhuravlev, Alejandro Cruz, Vladislav Aksenov, Alexey Golovanov, José M. Lluch, Hartmut Kuhn, Àngels González-Lafont, Igor Ivanov
Publikováno v:
Molecules, Vol 28, Iss 14, p 5418 (2023)
Mammalian 15-lipoxygenases (ALOX15) are lipid peroxidizing enzymes that exhibit variable functionality in different cancer and inflammation models. The pathophysiological role of linoleic acid- and arachidonic acid-derived ALOX15 metabolites rendered
Externí odkaz:
https://doaj.org/article/b3192ec52c6a4506b2e37cd8615decaa
Autor:
Kumar R. Kakularam, Miquel Canyelles-Niño, Xin Chen, José M. Lluch, Àngels González-Lafont, Hartmut Kuhn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10046 (2023)
The arachidonic acid lipoxygenase 15B (ALOX15B) orthologs of men and mice form different reaction products when arachidonic acid is used as the substrate. Tyr603Asp+His604Val double mutation in mouse arachidonic acid lipoxygenase 15b humanized the pr
Externí odkaz:
https://doaj.org/article/4a9bba2dd3ea48e68f9ffd1ebb2a59d9
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6064 (2023)
Human lipoxygenase 12 (hALOX12) catalyzes the conversion of docosahexaenoic acid (DHA) into mainly 14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (14S-H(p)DHA). This hydroperoxidation reaction is followed by an epoxidation and hydrolysis
Externí odkaz:
https://doaj.org/article/4dec4ad2f96a4cbcb10f5c3681c3d52c
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 25 (2022)
Simulations based on molecular dynamics coupled to excitation energy calculations were used to generate simulated absorption spectra for a family of halide derivatives of azobenzene, a family of photoswitch molecules with a weak absorption band aroun
Externí odkaz:
https://doaj.org/article/76c416093d2f4b1abc882e637877ebff
Autor:
Victor A. Streltsov, Sukanya Luang, Alys Peisley, Joseph N. Varghese, James R. Ketudat Cairns, Sebastien Fort, Marcel Hijnen, Igor Tvaroška, Ana Ardá, Jesús Jiménez-Barbero, Mercedes Alfonso-Prieto, Carme Rovira, Fernanda Mendoza, Laura Tiessler-Sala, José-Emilio Sánchez-Aparicio, Jaime Rodríguez-Guerra, José M. Lluch, Jean-Didier Maréchal, Laura Masgrau, Maria Hrmova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Enzyme substrates and products often diffuse too rapidly to assess the catalytic implications of these movements. Here, the authors characterise the structural basis of product and substrate diffusion for an exo-hydrolase and discover a substrate-pro
Externí odkaz:
https://doaj.org/article/393023e627f645a0b2087690681cc2f6
Autor:
Gisela Cabré, Aida Garrido-Charles, Miquel Moreno, Miquel Bosch, Montserrat Porta-de-la-Riva, Michael Krieg, Marta Gascón-Moya, Núria Camarero, Ricard Gelabert, José M. Lluch, Félix Busqué, Jordi Hernando, Pau Gorostiza, Ramon Alibés
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Two-photon absorption capacity of azobenzene photoswitches usually comes with a reduction in thermal stability. Here, the authors developed photoswitches with high two-photon sensitivity and enhanced cis isomer thermal lifetime for the control of glu
Externí odkaz:
https://doaj.org/article/9114c59db4034fbe97bb30bb46a1e2cd
Publikováno v:
ACS Omega, Vol 4, Iss 1, Pp 2063-2074 (2019)
Externí odkaz:
https://doaj.org/article/bb7ea1b0f5fc4c09bffe5648510a9f55
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8690 (2022)
In order to theoretically design multi-state photoswitches with specific properties, an exhaustive computational study is first carried out for an azobenzene dimer that has been recently synthesized and experimentally studied. This study allows for a
Externí odkaz:
https://doaj.org/article/428676453a5540479d135dd1953408d0