Zobrazeno 1 - 10
of 185
pro vyhledávání: '"M Lienhard Schmitz"'
Autor:
Michael Poppe, Sascha Wittig, Liane Jurida, Marek Bartkuhn, Jochen Wilhelm, Helmut Müller, Knut Beuerlein, Nadja Karl, Sabin Bhuju, John Ziebuhr, M Lienhard Schmitz, Michael Kracht
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006286 (2017)
Coronavirus replication takes place in the host cell cytoplasm and triggers inflammatory gene expression by poorly characterized mechanisms. To obtain more insight into the signals and molecular events that coordinate global host responses in the nuc
Externí odkaz:
https://doaj.org/article/5360acc7ff904d7fbc39af9d12d4e187
Autor:
Christin Klenke, Darius Widera, Thomas Engelen, Janine Müller, Thomas Noll, Karsten Niehaus, M Lienhard Schmitz, Barbara Kaltschmidt, Christian Kaltschmidt
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65280 (2013)
Signaling via NF-κB in neurons depends on complex formation with interactors such as dynein/dynactin motor complex and can be triggered by synaptic activation. However, so far a detailed interaction map for the neuronal NF-κB is missing. In this st
Externí odkaz:
https://doaj.org/article/f61d7f07f49e49418e8eb961bd88150b
Autor:
Holger Buss, Katja Handschick, Nadine Jurrmann, Pirita Pekkonen, Knut Beuerlein, Helmut Müller, Robin Wait, Jeremy Saklatvala, Päivi M Ojala, M Lienhard Schmitz, Michael Naumann, Michael Kracht
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51847 (2012)
Nuclear factor kappa-B (NF-κB) activates multiple genes with overlapping roles in cell proliferation, inflammation and cancer. Using an unbiased approach we identified human CDK6 as a novel kinase phosphorylating NF-κB p65 at serine 536. Purified a
Externí odkaz:
https://doaj.org/article/f0f07af112614169b2d732e1310cee77
Autor:
Maximilian Pfisterer, Roman Robert, Vera V. Saul, Amelie Pritz, Markus Seibert, Regina Feederle, M. Lienhard Schmitz
Publikováno v:
Open Biology, Vol 14, Iss 5 (2024)
The precise spatial and temporal control of histone phosphorylations is important for the ordered progression through the different phases of mitosis. The phosphorylation of H2B at S6 (H2B S6ph), which is crucial for chromosome segregation, reaches i
Externí odkaz:
https://doaj.org/article/d9c48c0e6cf1457c98b0f4f9b29b035f
Autor:
Mohammed Samer Shaban, Christin Mayr-Buro, Johanna Meier-Soelch, Benadict Vincent Albert, M. Lienhard Schmitz, John Ziebuhr, Michael Kracht
Publikováno v:
Trends in Pharmacological Sciences. 43:557-568
Despite the great success of vaccines that protect against RNA virus infections, and the development and clinical use of a limited number of RNA virus-specific drugs, there is still an urgent need for new classes of antiviral drugs against circulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6644f5e8c034bc14e582181c551b9220
https://doi.org/10.1016/j.tips.2022.04.004
https://doi.org/10.1016/j.tips.2022.04.004
Autor:
Lu Liu, Ramakanth Madhugiri, Vera Vivian Saul, Susanne Bacher, Michael Kracht, Stephan Pleschka, M. Lienhard Schmitz
Publikováno v:
Scientific Reports. 13
The influenza A virus (IAV) polymerase is a multifunctional machine that can adopt alternative configurations to perform transcription and replication of the viral RNA genome in a temporally ordered manner. Although the structure of polymerase is wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180539d8be569e1302ad967f37c20d1b
https://doi.org/10.1038/s41598-023-34285-7
https://doi.org/10.1038/s41598-023-34285-7
Autor:
Xi Yang, Shi-Ting Wu, Rui Gao, Rui Wang, Yixuan Wang, Zhenkun Dong, Lu Wang, Chunxiao Qi, Xiaohong Wang, M. Lienhard Schmitz, Renjing Liu, Zhiming Han, Xiangjian Zheng
Publikováno v:
JCI Insight. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200d25657fec0eb44c7b60c37c164184
https://doi.org/10.1172/jci.insight.160372
https://doi.org/10.1172/jci.insight.160372
Autor:
Lu Liu, Axel Weber, Uwe Linne, Mahmoud Shehata, Stephan Pleschka, Michael Kracht, M. Lienhard Schmitz
Publikováno v:
mBio.
The influenza A virus (IAV)-encoded matrix protein 1 (M1) acts as a master regulator of virus replication and fulfills multiple structural and regulatory functions in different cell compartments. Therefore, the spatiotemporal regulation of M1 is achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73335583df474b9f19b91b2739313c45
https://pubmed.ncbi.nlm.nih.gov/36602306
https://pubmed.ncbi.nlm.nih.gov/36602306
Autor:
Mohammed Samer, Shaban, Christin, Müller, Christin, Mayr-Buro, Hendrik, Weiser, Johanna, Meier-Soelch, Benadict Vincent, Albert, Axel, Weber, Uwe, Linne, Torsten, Hain, Ilya, Babayev, Nadja, Karl, Nina, Hofmann, Stephan, Becker, Susanne, Herold, M Lienhard, Schmitz, John, Ziebuhr, Michael, Kracht
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications
Nature Communications
Coronaviruses (CoVs) are important human pathogens for which no specific treatment is available. Here, we provide evidence that pharmacological reprogramming of ER stress pathways can be exploited to suppress CoV replication. The ER stress inducer th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::05325e20a1311b564eb3fdb01400bec4
https://doaj.org/article/a6f9af13b42d437eab2e9eaf4c3fe912
https://doaj.org/article/a6f9af13b42d437eab2e9eaf4c3fe912
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4e518253751e66c57678fa761da133e
https://doi.org/10.1007/978-1-0716-2788-4_24
https://doi.org/10.1007/978-1-0716-2788-4_24
