Zobrazeno 1 - 10
of 171
pro vyhledávání: '"M Li-Weber"'
Publikováno v:
The Journal of Immunology. 158:1194-1200
The immunomodulatory cytokine IL-4 affects cells of most hemopoietic lineages. IL-4 is secreted by activated Th2 but not Th1 cells and plays a major role in the immune response by modulating the differentiation of naive Th cells toward the Th2 phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103f0b379d73a1f8d22b49df2bc9a5d8
https://doi.org/10.4049/jimmunol.158.3.1194
https://doi.org/10.4049/jimmunol.158.3.1194
Publikováno v:
The Journal of Immunology. 155:5273-5279
Positive regulatory element I (PRE-I) is a strong enhancer element essential for expression of the human IL-4 gene. To identify transcription factors binding to PRE-I, we screened a cDNA expression library from Jurkat T cells and isolated a cDNA enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0011666c94201ef37b95dfd5203d1ce
https://doi.org/10.4049/jimmunol.155.11.5273
https://doi.org/10.4049/jimmunol.155.11.5273
Publikováno v:
The Journal of Immunology. 153:4122-4133
Activity of the IL-4 promoter was shown to be regulated by multiple cis-acting elements. In this study, two additional regulatory elements, a CCAAT element and a 15-nucleotide element homologous to the IFN- and virus-stimulation response element (ISR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbcdc9c1d61baa66edf14658825f3ce6
https://doi.org/10.4049/jimmunol.153.9.4122
https://doi.org/10.4049/jimmunol.153.9.4122
A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer
Publikováno v:
The Journal of Immunology. 151:1371-1382
IL-4 is a pleiotropic cytokine that regulates T cell-dependent immune responses. We identified and characterized a novel enhancer, positive regulatory element I (PRE-I), in the 5' region of the promoter of the human IL-4 gene. The functional core ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c349a5b6d6c0c7cb95b5b8643586cd3a
https://doi.org/10.4049/jimmunol.151.3.1371
https://doi.org/10.4049/jimmunol.151.3.1371
Publikováno v:
The Journal of Immunology. 148:1913-1918
IL-4 secreted by activated T cells is a pleiotropic cytokine affecting growth and differentiation of diverse cell types such as T cells, B cells, and mast cells. We investigated the upstream regulatory elements of the human IL-4 promoter. A novel T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d23aa87e306eaf6c4c719175de3b0bc
https://doi.org/10.4049/jimmunol.148.6.1913
https://doi.org/10.4049/jimmunol.148.6.1913
Autor:
Mohamed M.M. Abdel-Latif, Henry J. Windle, Katherine A. Fitzgerald, D. Ni Eidhin, Daniel J. Kelleher, Yeng Ang, M. Li-Weber, Kamal Sabra
PUBLISHED
The early growth response 1 (Egr-1) transcription factor is rapidly induced by various stimuli and is implicated in the regulation of cell growth, differentiation, and gene expression. The aim of this study was to examine the effect of
The early growth response 1 (Egr-1) transcription factor is rapidly induced by various stimuli and is implicated in the regulation of cell growth, differentiation, and gene expression. The aim of this study was to examine the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7510db72f8819cad7e15d16e263c0b0b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
European journal of immunology. 30(10)
Efficient activation of antigen-specific T cells requires co-stimulatory signals provided e.g. by CD28. Re-exposure to antigen and CD28 co-stimulation reduces activation-induced cell death (AICD) and increases the number of T cells performing effecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64720095fc5dbfe619564b342ad1d480
https://pubmed.ncbi.nlm.nih.gov/11069056
https://pubmed.ncbi.nlm.nih.gov/11069056
Publikováno v:
European journal of immunology. 30(2)
CD95(APO-1 / Fas) ligand (CD95L) gene expression is critically involved in activation-induced T cell apoptosis. We and other have previously shown that HIV-1 Tat which is essential for efficient HIV gene expression sensitizes CD95-mediated apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::459cdde191558eea33c33293eaed2975
https://pubmed.ncbi.nlm.nih.gov/10671224
https://pubmed.ncbi.nlm.nih.gov/10671224
Autor:
Henning Schulze-Bergkamen, M. Müller-Schilling, Sören T. Eichhorst, M. Li-Weber, Peter H. Krammer
Publikováno v:
Journal of Hepatology. 32:47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0cce869503e34644e130e017775a2f6
https://doi.org/10.1016/s0168-8278(00)80511-5
https://doi.org/10.1016/s0168-8278(00)80511-5