Zobrazeno 1 - 10
of 133
pro vyhledávání: '"M L Kripke"'
Publikováno v:
Photochemistry and Photobiology. 71:743-746
Publikováno v:
The Journal of Immunology. 157:2891-2899
Urocanic acid (UCA) occurs naturally in the stratum corneum of the skin as the trans-isomer and, upon exposure to UVB radiation, converts to cis-UCA. It has been proposed that trans-UCA is the photoreceptor for and, following its isomerization to cis
Publikováno v:
The Journal of Immunology. 157:781-786
We have developed a model for studying the role of local immunologic mechanisms in tumor development, in which injection of K1735 melanoma cells into the UV-irradiated ears of C3H mice results in a significantly higher incidence of tumors than inject
Autor:
C D Love-Schimenti, M L Kripke
Publikováno v:
The Journal of Immunology. 153:3450-3456
Hapten-conjugated cells of the dendritic epidermal T cell (DETC) line AU16 induce specific immunologic tolerance in vivo and inhibit the proliferation of native T cells in response to hapten-bearing dendritic cells in vitro. The purpose of this study
Autor:
J Alcalay, M L Kripke
Publikováno v:
The Journal of Immunology. 146:1717-1721
The induction of skin cancers in mice by chronic UV irradiation is accompanied by a decrease in the numbers of Ia+ and Thy-1+ dendritic cells in the epidermis early in the course of UV irradiation. Subsequently, the number of Ia+ cells, but not Thy-1
Publikováno v:
The Journal of Immunology. 145:2833-2838
These studies address the hypothesis that Ag-bearing epidermal Langerhans cells migrate to the regional lymph node during contact sensitization and function as APC. Skin from C3H mice was grafted onto BALB/c nude mice, and 7 or 14 days later, the rec
Autor:
E A Welsh, M L Kripke
Publikováno v:
The Journal of Immunology. 144:883-891
To study the potential immunologic functions of murine Thy-1+ dendritic epidermal cells (Tdec), we used long term, IL-2-dependent, Tdec lines derived from the skin of C3H mice. Cells of the Tdec lines AU16 or AU4 were conjugated in vitro with the hap
Publikováno v:
Photochemistry and photobiology. 73(5)
These studies addressed the hypothesis that UV radiation (UVR) could affect immune responses in mice infected with Borrelia burgdorferi. Immunity against the Lyme spirochete B. burgdorferi was studied in a murine model of UV-induced immune suppressio
Persistence of immunogenic pulmonary metastases in the presence of protective anti-melanoma immunity
Publikováno v:
Cancer research. 61(1)
We have developed a murine melanoma model that allows us to investigate the mechanisms by which spontaneous, immunogenic melanoma metastases escape immunological destruction in syngeneic mice. In the current study, we tested the hypothesis that loss