Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M L Hooper"'
Publikováno v:
Acta Ophthalmologica. 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c2c27f033eeba723d12a4b352627c84
https://doi.org/10.1111/j.1755-3768.2022.15568
https://doi.org/10.1111/j.1755-3768.2022.15568
Autor:
M L Hooper
Publikováno v:
British Journal of Cancer
The incidence of unilateral, but not bilateral, retinoblastoma in human populations at different geographical locations increases significantly with ambient erythemal dose of ultraviolet B radiation from sunlight. This supports the hypothesis that su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616f1230868230308d5591a7442f0f2b
http://europepmc.org/articles/PMC2362220
http://europepmc.org/articles/PMC2362220
Publikováno v:
Methods in molecular medicine. 1
Immediate-early genes (IEGs) are members of a class of genes that respond, in many cell types, to a variety of stimuli by rapid, but transient expression (1). Several of these IEGs code for transcription factors and include the widely studied activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f78387b996be63f18a6db4d0c21fe33c
https://pubmed.ncbi.nlm.nih.gov/21359726
https://pubmed.ncbi.nlm.nih.gov/21359726
Publikováno v:
Blood. 82:1445-1452
The mouse Pim-1 gene encodes two cytoplasmic serine-threonine-specific protein kinases. The gene has been found to be activated (overexpressed) by retroviral insertion in hematopoietic tumors in mice. Transgenic mice that overexpress Pim-1 (E mu-Pim-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a75969933d786ed910511ae13ec914
https://doi.org/10.1182/blood.v82.5.1445.bloodjournal8251445
https://doi.org/10.1182/blood.v82.5.1445.bloodjournal8251445
Autor:
B B Cohen, I E Young, V A Anderson, M L Hooper, C Annink, Kathreena M Kurian, Ian Kunkler, C. M. Steel, Andrew H. Wyllie
Publikováno v:
British Journal of Cancer
The CYP17 gene codes for the cytochrome P450c17α enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea9a043f271db0ea5471cc858e3fb7e
http://europepmc.org/articles/PMC2374358
http://europepmc.org/articles/PMC2374358
Autor:
S J, Plowman, R L, Berry, S A, Bader, F, Luo, M J, Arends, D J, Harrison, M L, Hooper, C E, Patek
Publikováno v:
Journal of experimentalclinical cancer research : CR. 25(2)
Ras activating mutations result in constitutive activation of Ras signalling pathways and occur in 30% of human malignancies. K-ras encodes two splice variants, K-ras 4A and 4B, and K-ras activating mutations which jointly affect both isoforms are pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0792bcca932085d2e6898ce9d81e582
https://pubmed.ncbi.nlm.nih.gov/16918139
https://pubmed.ncbi.nlm.nih.gov/16918139
Autor:
A H, Wyllie, C O, Bellamy, V J, Bubb, A R, Clarke, S, Corbet, L, Curtis, D J, Harrison, M L, Hooper, N, Toft, S, Webb, C C, Bird
Publikováno v:
British journal of cancer. 80
Apoptosis has long been known to be effected through a common sequence of structural changes, despite the wide variety of initiating stimuli. These common structural events appear to depend upon activation of a set of enzymes (caspases) which direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::290f063c7f3472aa4957957870f882cf
https://pubmed.ncbi.nlm.nih.gov/10466759
https://pubmed.ncbi.nlm.nih.gov/10466759
Publikováno v:
Oncogene. 10(8)
We describe the pathology of a cohort of 80 mice heterozygous for an inactive allele of the Rb-1 tumour suppressor gene. The majority of these mice developed locally invasive tumours, arising from the pituitary gland. The time of onset of overt signs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0443d7b8aeb77c2e3d4756eca9e2d30c
https://pubmed.ncbi.nlm.nih.gov/7731716
https://pubmed.ncbi.nlm.nih.gov/7731716
Publikováno v:
Oncogene. 9(6)
p53 is now well characterized as a tumour suppressor gene, with loss of normal p53 function being recorded as the commonest genetic event associated with human malignancy. In particular, its involvement with tumorigenesis within the intestine is well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcddf3dd3fa1242503393e660f0eca14
https://pubmed.ncbi.nlm.nih.gov/8183575
https://pubmed.ncbi.nlm.nih.gov/8183575
Autor:
S, Itohara, P, Mombaerts, J, Lafaille, J, Iacomini, A, Nelson, A R, Clarke, M L, Hooper, A, Farr, S, Tonegawa
Publikováno v:
Cell. 72(3)
T cells bearing T cell receptor (TCR) gamma and delta chain heterodimers are first generated early in ontogeny. They form distinct subsets that differ in their TCR repertoires and tissue distribution. Disruption of the mouse TCR C delta gene segment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34dc7f8fd3007af1f5d3439a8efe963f
https://pubmed.ncbi.nlm.nih.gov/8381716
https://pubmed.ncbi.nlm.nih.gov/8381716