Zobrazeno 1 - 10 of 20 pro vyhledávání: '"M L Dustin"'
1
Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions
Autor: G Ganpule, R Knorr, J M Miller, C P Carron, M L Dustin
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a8ddfd71df5da3a8e45257fe45409e
https://ora.ox.ac.uk/objects/uuid:4d2fed34-afab-40ce-9599-098f6b0ed6cc
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2
Role of adhesion molecules in activation signaling in T lymphocytes
Autor: M L, Dustin
Publikováno v: Journal of clinical immunology. 21(4)
The T cell and antigen-presenting cell communicate to initiate an immune response through formation of an immunological synapse. This specialized cell-cell junction is compartmentalized into adhesion molecule and T cell receptor enriched regions or S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9edc1f8ff0fd1e640deb3364986e3c5f
https://pubmed.ncbi.nlm.nih.gov/11506195
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5
Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration
Autor: Z M, Ding, J E, Babensee, S I, Simon, H, Lu, J L, Perrard, D C, Bullard, X Y, Dai, S K, Bromley, M L, Dustin, M L, Entman, C W, Smith, C M, Ballantyne
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(9)
To differentiate the unique and overlapping functions of LFA-1 and Mac-1, LFA-1-deficient mice were developed by targeted homologous recombination in embryonic stem cells, and neutrophil function was compared in vitro and in vivo with Mac-1-deficient
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::51342e7c57f63e80193419566bd5612c
https://pubmed.ncbi.nlm.nih.gov/10528208
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6
Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions
Autor: G, Ganpule, R, Knorr, J M, Miller, C P, Carron, M L, Dustin
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(6)
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::608c31a5fd6cccb98a679c20bc43fc9c
https://pubmed.ncbi.nlm.nih.gov/9300688
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7
TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment
Autor: M L, Dustin, J M, Miller, S, Ranganath, D A, Vignali, N J, Viner, C A, Nelson, E R, Unanue
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 157(5)
T cell recognition of foreign Ag/MHC class II complexes is sensitive down to approximately 100 complexes per cell or approximately 0.2 complexes/micron2. To better understand the physical basis of the recognition stage of Ag presentation, we examined
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::217123017f358f7824aecd35f2979276
https://pubmed.ncbi.nlm.nih.gov/8757322
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8
A mannose 6-phosphate-containing N-linked glycopeptide derived from lysosomal acid lipase is bound to MHC class II in B lymphoblastoid cell lines
Autor: M L, Dustin, D W, McCourt, S, Kornfeld
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(5)
Binding of peptides to MHC class II Ag generates ligands for TCR of Th lymphocytes. We have identified a novel class of peptides bound to MHC class II: mannose 6- phosphate (Man-6-P) containing glycopeptides from lysosomal enzymes. These species were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aa738bc936eca1543bedf3f74389f184
https://pubmed.ncbi.nlm.nih.gov/8596035
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9
Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors
Autor: M L Dustin, O Carpen, T A Springer
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(9)
We demonstrate complementary differences in the behavior of B lymphoblastoid cells adhering to LFA-1 or its counter-receptor ICAM-1. The interaction of B lymphoblastoid cells with glass-supported planar bilayers bearing LFA-1 or ICAM-1 was observed b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744b018e3ca6dfbbfc0bb90c69f7c652
http://ora.ox.ac.uk/objects/uuid:521cd765-0db5-4bd8-9f30-b011afdaca12
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10
On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules
Autor: S C, Johnston, M L, Dustin, M L, Hibbs, T A, Springer
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 145(4)
Species restrictions in immune cell interactions have been demonstrated both in Ag-specific responses of T lymphocytes and the phenomenon of natural attachment. To determine the possible contribution of adhesion receptors to these restrictions, we ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::280c8db89071f9b753c6453a4ee63fa5
https://pubmed.ncbi.nlm.nih.gov/2199576
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