Zobrazeno 1 - 10
of 842
pro vyhledávání: '"M L Dias"'
Autor:
M. L. Dias, J. C. L. Silva
Publikováno v:
Scientific Electronic Archives, Vol 13, Iss 6, Pp 102-112 (2020)
In recent decades, consumption of illicit substances has become a concern of society, a public health problem due to the high incidence of social problems related to its use and the risks to users' health. The transition period to the university is a
Externí odkaz:
https://doaj.org/article/d2286f1797104b0e8e6ffbdf6019c02e
Autor:
Rebecca Caeser, Miriam Di Re, Joanna A. Krupka, Jie Gao, Maribel Lara-Chica, João M. L. Dias, Susanna L. Cooke, Rachel Fenner, Zelvera Usheva, Hendrik F. P. Runge, Philip A. Beer, Hesham Eldaly, Hyo-Kyung Pak, Chan-Sik Park, George S. Vassiliou, Brian J. P. Huntly, Annalisa Mupo, Rachael J. M. Bashford-Rogers, Daniel J. Hodson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
A dearth of adequate preclinical models to faithfully mimic diffuse large B-cell lymphoma has hampered the identification of driver genes. Here, the authors present a co-culture system that enables ex vivo expansion, viral transduction and transforma
Externí odkaz:
https://doaj.org/article/d3c9bc11a5cc4cb39c1c847ddd0e75b2
Autor:
Araceli Queiruga-Dios, María Jesus Santos Sánchez, Fatih Yilmaz, Deolinda M. L. Dias Rasteiro, Jesús Martín-Vaquero, Víctor Gayoso Martínez
Publikováno v:
Mathematics, Vol 10, Iss 19, p 3412 (2022)
This book contains the successful submissions [...]
Externí odkaz:
https://doaj.org/article/9b18ce993b85474c92687f4fd292cad9
Autor:
Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M. S. Vijayabaskar, Wen-Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D. Toop, Monika Dudek, Samuel C. Robson, Francisco Hermida-Prado, Yu Hsuen Yang, Roya Babaei-Jadidi, Dimitrios A. Garyfallos, Hannes Ponstingl, Joao M. L. Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J. Bannister, Roland Rad, Rab K. Prinjha, John C. Marioni, Brian Huntly, Jennifer Batson, Jonathan C. Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O. Bates, Kosuke Yusa, Tony Kouzarides, George S. Vassiliou
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
SRPK1, a kinase involved in splicing regulation, is a potential therapeutic target for AML patients. Here, the authors show that SRPK1 inhibition changes isoform levels of key epigenetic regulators, including BRD4, and it has anti-tumor effects speci
Externí odkaz:
https://doaj.org/article/1853a1ced0ff46dfaf75bec9896c8581
Autor:
Cherif Badja, Sophie Momen, Gene Ching Cheik Koh, Soraya Boushaki, Theodoros I. Roumeliotis, Zuza Kozik, Ian Jones, Vicky Bousgouni, João M. L. Dias, Marios G. Krokidis, Jamie Young, Hongwei Chen, Ming Yang, France Docquier, Yasin Memari, Lorea Valcarcel-Jimenez, Komal Gupta, Li Ren Kong, Heather Fawcett, Florian Robert, Salome Zhao, Andrea Degasperi, Helen Davies, Rebecca Harris, Christian Frezza, Chryssostomos Chatgilialoglu, Robert Sarkany, Alan Lehmann, Chris Bakal, Jyoti Choudhary, Hiva Fassihi, Serena Nik-Zainal
Xeroderma pigmentosum (XP) is characterized by defective repair of ultraviolet radiation(UVR)-induced DNA damage. Patients have UVR hypersensitivity and increased skin cancer risk. Effective photoprotection has reduced childhood cancer-related deaths
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b233f67d5f67e6776714ccf87baf0001
https://doi.org/10.1101/2023.05.22.23290124
https://doi.org/10.1101/2023.05.22.23290124
Autor:
Sabrina Arena, Alberto Bardelli, Federica Di Nicolantonio, Serena Nik-Zainal, Andrea Sartore-Bianchi, Salvatore Siena, Silvia Marsoni, Michael Linnebacher, Pietro Andrei, Gianluca Mauri, Carlotta Cancelliere, Andrea Degasperi, Giorgio Corti, Simona Lamba, Federica Pisati, Gaia Grasso, João M. L. Dias, Annalisa Lorenzato, Rosaria Chilà, Elisa Mariella, Kristi Buzo, Nicole M. Reilly, Erika Durinikova
Supplementary Figure from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180032a9dec4f433f6ff89c4d0c666ad
https://doi.org/10.1158/1078-0432.22488176.v1
https://doi.org/10.1158/1078-0432.22488176.v1
Autor:
Sabrina Arena, Alberto Bardelli, Federica Di Nicolantonio, Serena Nik-Zainal, Andrea Sartore-Bianchi, Salvatore Siena, Silvia Marsoni, Michael Linnebacher, Pietro Andrei, Gianluca Mauri, Carlotta Cancelliere, Andrea Degasperi, Giorgio Corti, Simona Lamba, Federica Pisati, Gaia Grasso, João M. L. Dias, Annalisa Lorenzato, Rosaria Chilà, Elisa Mariella, Kristi Buzo, Nicole M. Reilly, Erika Durinikova
Supplementary Table from Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eacb7fca88384accbfb34b13a61c8d6
https://doi.org/10.1158/1078-0432.22488170
https://doi.org/10.1158/1078-0432.22488170
Autor:
Sabrina Arena, Alberto Bardelli, Federica Di Nicolantonio, Serena Nik-Zainal, Andrea Sartore-Bianchi, Salvatore Siena, Silvia Marsoni, Michael Linnebacher, Pietro Andrei, Gianluca Mauri, Carlotta Cancelliere, Andrea Degasperi, Giorgio Corti, Simona Lamba, Federica Pisati, Gaia Grasso, João M. L. Dias, Annalisa Lorenzato, Rosaria Chilà, Elisa Mariella, Kristi Buzo, Nicole M. Reilly, Erika Durinikova
Purpose:Genomic instability is a hallmark of cancer and targeting DNA damage response (DDR) is emerging as a promising therapeutic strategy in different solid tumors. The effectiveness of targeting DDR in colorectal cancer has not been extensively ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6003be7c1265b762d7f0da11f2e3ab9b
https://doi.org/10.1158/1078-0432.c.6532661.v1
https://doi.org/10.1158/1078-0432.c.6532661.v1
Autor:
Gene Koh, Sophie Momen, Yasin Memari, Jan Czarnecki, Ilias Georgakopoulos-Soares, Andrea Degasperi, Cherif Badja, Jamie Young, João M. L. Dias, Scott Shooter, Arjun Scott Nanda, Sandro Morganella, Xueqing Zou, Dominik Glodzik, Tauanne Dias Amarante, Serena Nik-Zainal, Helen Davies
Publikováno v:
Nature Cancer. 1:249-263
Mutational signatures are patterns of mutations that arise during tumorigenesis. We present an enhanced, practical framework for mutational signature analyses. Applying these methods on 3,107 whole genome sequenced (WGS) primary cancers of 21 organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d414019410a4c2a1986c63afaa3890
https://doi.org/10.1038/s43018-020-0027-5
https://doi.org/10.1038/s43018-020-0027-5
Autor:
Erika Durinikova, Nicole M. Reilly, Kristi Buzo, Elisa Mariella, Rosaria Chilà, Annalisa Lorenzato, João M. L. Dias, Gaia Grasso, Federica Pisati, Simona Lamba, Giorgio Corti, Andrea Degasperi, Carlotta Cancelliere, Gianluca Mauri, Pietro Andrei, Michael Linnebacher, Silvia Marsoni, Salvatore Siena, Andrea Sartore-Bianchi, Serena Nik-Zainal, Federica Di Nicolantonio, Alberto Bardelli, Sabrina Arena
Publikováno v:
Clinical Cancer Research
Purpose: Genomic instability is a hallmark of cancer and targeting DNA damage response (DDR) is emerging as a promising therapeutic strategy in different solid tumors. The effectiveness of targeting DDR in colorectal cancer has not been extensively e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4a4edbc830946b7de43e7c14546f28