Zobrazeno 1 - 10
of 21
pro vyhledávání: '"M L Breitman"'
Publikováno v:
Genes & Development. 7:295-307
The vertebrate lens is a classical system for examining mechanisms of tissue determination and differentiation, yet little is known about the signaling molecules controlling its development. Here, we report that retinoic acid (RA), a substance known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c19e026a8344e4e952be94b0d03d9f
https://doi.org/10.1101/gad.7.2.295
https://doi.org/10.1101/gad.7.2.295
Publikováno v:
Molecular and Cellular Biology. 10:474-479
We have previously generated microphthalmic mice lacking lens fiber cells by targeting the expression of the diphtheria toxin A (DT-A) gene in transgenic mice with regulatory sequences associated with the mouse gamma 2-crystallin gene. Because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2df6eff26f29932e846ea5b1eaa3fbd
https://doi.org/10.1128/mcb.10.2.474-479.1990
https://doi.org/10.1128/mcb.10.2.474-479.1990
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 207(1)
Flt-1 is a high affinity binding receptor for the vascular endothelial cell growth factor (VEGF) and is primarily expressed in endothelial cells. In this study we have investigated the temporal and spatial regulation of its expression by establishing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::858632b6dc1d41c31718981dbf2cf765
https://pubmed.ncbi.nlm.nih.gov/8875071
https://pubmed.ncbi.nlm.nih.gov/8875071
Publikováno v:
Oncogene. 12(1)
Proteins of the Maf/Nrl subfamily of bZIP transcription factors are involved in the regulation of tissue-specific gene expression. The Nrl gene, initially identified from a subtracted retinal library, is expressed in all cell layers of the adult reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b0139a16228084da3a5061d57169dbb
https://pubmed.ncbi.nlm.nih.gov/8552394
https://pubmed.ncbi.nlm.nih.gov/8552394
Publikováno v:
Oncogene. 9(9)
Transgenic mice expressing v-jun under the control of the H-2K promoter develop dermal fibrosarcomas and rhabdomyosarcomas via a multistep process following wounding. To assess the relative roles that wounding and the H-2K promoter play in this proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd72109bca9a2eba69439231c1aabd05
https://pubmed.ncbi.nlm.nih.gov/8058321
https://pubmed.ncbi.nlm.nih.gov/8058321
Publikováno v:
Oncogene. 8(6)
Regulatory elements of the mouse gamma F-crystallin gene were used to derive transgenic mice expressing SV40 large T antigen in terminally differentiating fiber cells of the ocular lens. The resulting gamma F-crystallin-T antigen mice developed eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52a6dcf51faa49655a50397ca3ca4278
https://pubmed.ncbi.nlm.nih.gov/8389033
https://pubmed.ncbi.nlm.nih.gov/8389033
Publikováno v:
Oncogene. 8(5)
We have cloned a 4.2-kb murine cDNA encoding the Tek receptor tyrosine kinase (RTK), which is expressed in endothelial cells and their progenitors. The 1122-residue protein contains an extracellular domain comprising three fibronectin type III repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1792398019361d322e5b5642ba6da209
https://pubmed.ncbi.nlm.nih.gov/8386827
https://pubmed.ncbi.nlm.nih.gov/8386827
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 4(3)
H-2K/v-jun transgenic mice develop sarcomas at sites of wounding via a multistep process characterized by discrete pathological stages. To study this progression in vitro, cells from different stages of tumorigenesis were cultured and examined for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7182226071fd8fc9b29aa7ac0f8f6b96
https://pubmed.ncbi.nlm.nih.gov/8466856
https://pubmed.ncbi.nlm.nih.gov/8466856
Publikováno v:
Oncogene. 7(8)
A search for protein tyrosine kinases expressed during murine cardiogenesis resulted in the isolation of a novel tyrosine kinase, designated tek, which maps to mouse chromosome 4 between the brown and pmv-23 loci. The deduced amino acid sequence of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c21ec218690c794e108cb8086210b63
https://pubmed.ncbi.nlm.nih.gov/1630810
https://pubmed.ncbi.nlm.nih.gov/1630810
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 67(1)
Transgenic mice in which elongating lens fiber cells were ablated resulting in microphthalmia have been reported, however, their embryology and detailed morphology have not.The morphology of homozygous and hemizygous CDI, transgenic mice carrying the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9de6a27b37d957355a8a1ffc2fcb7844
https://pubmed.ncbi.nlm.nih.gov/1625446
https://pubmed.ncbi.nlm.nih.gov/1625446