Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre- and post-treatment biopsies in the multi-center SAKK19/09 study

Autor: M L Amrein, S Savic-Prince, Adrian F. Ochsenbein, Michael A. Amrein, Elias D. Bührer, Rolf Jaggi, Sacha I. Rothschild, Lukas Bubendorf, Qiyu Li, Carsten Riether, O. Gautschi

Publikováno v: Amrein, M. A.; Bührer, E. D.; Amrein, M. L.; Li, Q.; Rothschild, S.; Riether, C.; Jaggi, R.; Savic-Prince, S.; Bubendorf, L.; Gautschi, O.; Ochsenbein, A. (2021). Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre-and post-treatment biopsies in the multi-center SAKK19/09 study. Cancer immunology, immunotherapy : CII, 70(2), pp. 405-415. Springer 10.1007/s00262-020-02688-4
Cancer Immunology, Immunotherapy

Background Over the past few years, immune checkpoint inhibitors have changed the therapeutic landscape of non-small-cell lung cancer (NSCLC). Response to immune checkpoint inhibitors correlates with a pre-existing anti-tumoral immune response. Check

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https://doi.org/10.1007/s00262-020-02688-4