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pro vyhledávání: '"M L, Vo Van"'
Autor:
M-L Vo Van, R Abbas, Y Zhao, D. Hershman, Sangeeta Gupta, Amy Freyman, L. Chow, Igor Bondarenko, Richard J. Epstein, Ahmad Awada
Publikováno v:
Cancer Research. 70:P3-14
Background: Neratinib (HKI-272), an irreversible inhibitor of the tyrosine kinase receptors Her1, -2 and -4, has shown antitumor activity in patients with Her2+ disease, with or without prior trastuzumab exposure. In preclinical models, neratinib inh
Autor:
M-L Vo Van, Richat Abbas, T Luu, Binghe Xu, E. Staroslawska, V. Agrapart, A Berkenblit, Christine Powell, J Yang, Luis Manso, A Strahs, Véronique Diéras, L.Y. Dirix, Ahmad Awada
Publikováno v:
Cancer Research. 70:P3-14
Background: Neratinib (HKI-272) is an irreversible pan-ErbB tyrosine kinase inhibitor that blocks downstream signaling of the ErbB1, -2, and -4 receptors and has shown antitumor activity in patients with ErbB2+ breast cancer. Vinorelbine has shown sy
Autor:
Y Zhao, L W-C Chow, Binghe Xu, M-L Vo Van, Igor Bondarenko, Amy Freyman, Sangeeta Gupta, R Abbas
Publikováno v:
British Journal of Cancer
Introduction: Neratinib is a potent irreversible pan-ErbB tyrosine kinase inhibitor that has demonstrated antitumour activity and an acceptable safety profile in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer and
Publikováno v:
Cancer Investigation. 11:135-139
Thirty patients with previously untreated and measurable or evaluable advanced soft tissue sarcoma entered this phase II study. Median age was 53 years (range: 24-71 years). Starting dose of Epirubicin was 100 mg/m2 IV bolus on day 1 combined with If
Autor:
J Mihura, P. Fargeot, Y. Devaux, M L Vo Van, M Mercier, P Fumoleau, S Schraub, M. Namer, P Kerbrat
Publikováno v:
Drugs. 45:38-45
Anthracyclines are among the most active drugs for the treatment of advanced breast cancer. Epirubicin has been found to be as effective as doxorubicin at equimolar doses but significantly better tolerated, especially in terms of alopecia, leucopenia
Autor:
P, Fumoleau, Y, Devaux, M L, Vo Van, P, Kerbrat, P, Fargeot, S, Schraub, J, Mihura, M, Namer, M, Mercier
Publikováno v:
Drugs. 45
Anthracyclines are among the most active drugs for the treatment of advanced breast cancer. Epirubicin has been found to be as effective as doxorubicin at equimolar doses but significantly better tolerated, especially in terms of alopecia, leucopenia
Publikováno v:
Bulletin du cancer. 77(10)
Thirty-seven patients (pts) with previously untreated and measurable advanced soft tissue sarcoma entered this phase II study: 22 men and 15 women were included. Median age was 58 (range: 20-71). The starting dose of epirubicin was 100 mg/m2 IV bolus
Publikováno v:
Presse medicale (Paris, France : 1983). 13(23)
Twenty-five patients with prostatic carcinoma were involved in a Gehan's oriented phase II trial of D-Trp6-LH-RH in daily doses of 500 mcg for 7 days and 100 mcg for 3 months, this lapse of time being considered optimal for evaluation of the short-te
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Akademický článek
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