Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M L, Toews"'
Autor:
Takanari Miyamoto, Sai Praneeth Reddy Bathena, D. R. Cerutis, Jiangeng Huang, M. L. Toews, Timothy P. McVaney, Lawrence C. Parrish, Yazen Alnouti, Martha E. Nunn, Melissa S. Lang
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 56:402-407
Lysophosphatidic acid (LPA) is a phospholipid mediator that plays multiple cellular functions by acting through G protein-coupled LPA receptors. LPAs are known to be key mediators in inflammation, and several lines of evidence suggest a role for LPAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d730051f396eb7055a36e1c7f32d5d76
https://doi.org/10.1016/j.jpba.2011.05.041
https://doi.org/10.1016/j.jpba.2011.05.041
Autor:
T L, Ediger, M L, Toews
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(3)
Previous studies showed that human airway smooth muscle (HASM) cells treated with lysophosphatidic acid (LPA), a pertussis toxin (PTX)-sensitive G protein-coupled (GPC) mitogen, simultaneously with epidermal growth factor (EGF), a receptor tyrosine k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a406f9aa6b50564e0c2231105db67916
https://pubmed.ncbi.nlm.nih.gov/10945862
https://pubmed.ncbi.nlm.nih.gov/10945862
Publikováno v:
Receptorssignal transduction. 6(3-4)
The effects of hypertonic sucrose and of intracellular potassium depletion on the intact-cell-binding properties of beta (beta AR) and alpha 1 (alpha 1AR) adrenergic receptors of DDT1 MF-2 hamster smooth muscle cells were investigated. These treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c25950f8c0c26905f38b3f9f59ba3818
https://pubmed.ncbi.nlm.nih.gov/9259048
https://pubmed.ncbi.nlm.nih.gov/9259048
Publikováno v:
Molecular pharmacology. 48(4)
The effects of the simple bioactive lipid mediator lysophosphatidic acid (LPA) on cAMP accumulation were investigated in cultured human airway smooth muscle cells (ASMC). Pretreatment of cells with LPA induced an increase in subsequent stimulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db056776239ef2d2c7c6be01ab10b575
https://pubmed.ncbi.nlm.nih.gov/7476905
https://pubmed.ncbi.nlm.nih.gov/7476905
Autor:
S J, Zhu, M L, Toews
Publikováno v:
Molecular pharmacology. 45(2)
During the course of equilibrium competition binding assays with intact cells, agonists induce conversion of beta-adrenergic receptors (BARs) from a native form with high affinity for agonists to a form with a markedly lower apparent affinity. The ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::226d5b395100923383a08e12682fcbde
https://pubmed.ncbi.nlm.nih.gov/7906855
https://pubmed.ncbi.nlm.nih.gov/7906855
Autor:
S J, Zhu, M L, Toews
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(1)
Depletion of intracellular ATP with antimycin A has been shown to inhibit the internalization of several types of receptors, including beta adrenergic and muscarinic acetylcholine receptors. The effects of antimycin A treatment on conversion of beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f88bc642d5b5231025e89506f16db4bf
https://pubmed.ncbi.nlm.nih.gov/8229739
https://pubmed.ncbi.nlm.nih.gov/8229739
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 264(3)
Preincubation of 1321N1 human astrocytoma cells in medium buffered with bicarbonate induced 50 to 100% increases in subsequent stimulation of cyclic AMP accumulation by the beta adrenergic receptor agonist isoproterenol and by the direct adenylyl cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caa6d0691036eb41f118794d04f41b92
https://pubmed.ncbi.nlm.nih.gov/7680717
https://pubmed.ncbi.nlm.nih.gov/7680717
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(3)
The effect of neuropeptide Y (NPY) on adenylate cyclase activity and the role of G-proteins mediating NPY's effect were investigated in cultured bovine adrenal chromaffin cells. The equilibrium binding of [125I]NPY to sucrose gradient purified bovine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e90f312064d34b8932de0fb2d651d46
https://pubmed.ncbi.nlm.nih.gov/1335068
https://pubmed.ncbi.nlm.nih.gov/1335068
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
Exposure of C62B rat glioma cells to fresh medium containing fetal bovine serum induced a sensitization of the subsequent ability of isoproterenol and forskolin to stimulate cyclic AMP accumulation, compared to cells exposed to fresh medium without s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27ada6d0e7038bc237f4a8c39584123f
https://pubmed.ncbi.nlm.nih.gov/1380077
https://pubmed.ncbi.nlm.nih.gov/1380077
Publikováno v:
Molecular pharmacology. 39(3)
Exposure of 1321N1 human astrocytoma cells to fresh medium containing fetal bovine serum induced a marked increase in the subsequent ability of isoproterenol and forskolin to stimulate cAMP accumulation in intact cells, compared with cells exposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b9714a6d5ef3defe0dde242b92c179d
https://pubmed.ncbi.nlm.nih.gov/1706472
https://pubmed.ncbi.nlm.nih.gov/1706472