Výsledky vyhledávání - "M L, Silverthorn"

Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate

Autor: R B, Rothman, M L, Silverthorn, J R, Glowa, D, Matecka, K C, Rice, F I, Carroll, J S, Partilla, G R, Uhl, D J, Vandenbergh, C M, Dersch

Publikováno v: Synapse (New York, N.Y.). 28(4)

[125I]RTI-55 is a cocaine analog with high affinity for dopamine (DA) and serotonin (5-HT) transporters. Quantitative ligand binding studies revealed a novel high affinity [125I]RTI-55 binding site assayed under 5-HT transporter (SERT) conditions whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08fbe4f1e08f5093e6f1fe68a94edc63
https://pubmed.ncbi.nlm.nih.gov/9517841

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Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate

Autor: R B, Rothman, M L, Silverthorn, M H, Baumann, C B, Goodman, J L, Cadet, D, Matecka, K C, Rice, F I, Carroll, J B, Wang, G R, Uhl

Publikováno v: The Journal of pharmacology and experimental therapeutics. 274(1)

Previous studies showed that the cocaine analog [125I]RTI-55 labels dopamine and serotonergic (5-HT) biogenic amine transporters (BATs) with high affinity. Here we characterized [125I]RTI-55 binding to membranes prepared from whole rat brain minus th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6403069812e7c0a655f90c63e1933381
https://pubmed.ncbi.nlm.nih.gov/7616423

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Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes

Autor: M L, Silverthorn, C M, Dersch, M H, Baumann, J L, Cadet, J S, Partilla, K C, Rice, F I, Carroll, K M, Becketts, A, Brockington, R B, Rothman

Publikováno v: The Journal of pharmacology and experimental therapeutics. 273(1)

Earlier work characterized the binding of the high-affinity cocaine analog 3 beta-(4-125iodophenyl)-tropane-2-carboxylic acid methyl ester ([125I]RTI-55) to membranes prepared from rat caudate. That investigation demonstrated that [125I]RTI-55-labele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bd8760bc5bc332b3717d46ab384f5d0a
https://pubmed.ncbi.nlm.nih.gov/7714769

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