Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M L, Schilsky"'
Autor:
D N, Assis, M L, Schilsky
Publikováno v:
Minerva gastroenterologica e dietologica. 56(3)
Caring for patients with advanced liver disease and acute liver failure requires a thorough understanding of the profound coagulation changes that occur in these conditions. Due to the unique nature of the pathophysiologic changes from hepatic dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbf783b0c1262ab92dc3feaec24e54b9
https://pubmed.ncbi.nlm.nih.gov/21037549
https://pubmed.ncbi.nlm.nih.gov/21037549
Publikováno v:
Biochemical Journal. 288:657-661
The blue copper protein caeruloplasmin is synthesized mainly by hepatocytes. An alternative transcript for caeruloplasmin produced in certain extrahepatic tissues, CP-1, contains an additional 12 nucleotides encoding 4 amino acids not present in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832b0cc04ac205eb8172a559be941fe3
https://doi.org/10.1042/bj2880657
https://doi.org/10.1042/bj2880657
Autor:
M L, Schilsky
Publikováno v:
Current opinion in gastroenterology. 15(3)
Our understanding of the pathophysiology and of new treatments for inherited metabolic diseases that affect the liver continues to grow through the study of gene mutations and their functional effect on the proteins they encode. For genetic hemochrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90b326e3348c02cb3b1508a831d877fb
https://pubmed.ncbi.nlm.nih.gov/17023946
https://pubmed.ncbi.nlm.nih.gov/17023946
Publikováno v:
Journal of biochemical and molecular toxicology. 14(4)
Copper toxicosis can occur in the absence of biliary copper excretion. To demonstrate whether biliary copper excretion capacity is correlated with hepatic mass and ATP7B function, we undertook studies in intact animals. Copper-histidine was injected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::448e548b79b6c0a58ed3f3c271b48069
https://pubmed.ncbi.nlm.nih.gov/10789499
https://pubmed.ncbi.nlm.nih.gov/10789499
Publikováno v:
Laboratory animal science. 48(2)
The Long-Evans Cinnamon (LEC) rat is a rodent model of Wilson's disease characterized by ceruloplasmin deficiency, hepatic copper accumulation, and hepatocellular injury. So far, the LEC rat appears to be the only strain in which cholangiofibrosis de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fa07c8e603f04b9a18fc3cd26199cec
https://pubmed.ncbi.nlm.nih.gov/10090006
https://pubmed.ncbi.nlm.nih.gov/10090006
Autor:
B R, Bacon, M L, Schilsky
Publikováno v:
Advances in internal medicine. 44
Discovery of the gene for WD has greatly enhanced our understanding of this disorder at the cellular level and has set the stage for future testing of new modes of therapy. Improvements in analytic methods for detecting mutations in genomic DNA will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b2e73eac1664fb19706d2e2e59e2c81
https://pubmed.ncbi.nlm.nih.gov/9929706
https://pubmed.ncbi.nlm.nih.gov/9929706
Autor:
M L, Schilsky
Publikováno v:
Hepatology (Baltimore, Md.). 22(4 Pt 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b3a6978c912b91a3a96453a785ad2c3
https://pubmed.ncbi.nlm.nih.gov/7557893
https://pubmed.ncbi.nlm.nih.gov/7557893
Autor:
I J, Fox, N R, Chowdhury, S, Gupta, R, Kondapalli, M L, Schilsky, R J, Stockert, J R, Chowdhury
Publikováno v:
Hepatology (Baltimore, Md.). 21(3)
Viral vectors and protein carriers utilizing asialoglycoprotein receptor (ASGR)-mediated endocytosis are being developed to transfer genes for the correction of bilirubin-UDP-glucuronosyltransferase (bilirubin-UGT) deficiency. Ex vivo evaluation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fc1f4726d77b26fb0a023c676444757
https://pubmed.ncbi.nlm.nih.gov/7875682
https://pubmed.ncbi.nlm.nih.gov/7875682
Autor:
Mark J. Czaja, A. Compton, L. W. Oberley, M. L. Schilsky, Yang Xu, L. Ridnour, P. Schmiedeberg
Publikováno v:
The American journal of physiology. 266(4 Pt 1)
The model of toxic liver injury was used to examine the role of manganese superoxide dismutase (MnSOD) expression in cellular resistance to tumor necrosis factor (TNF)-alpha toxicity. The effects of the hepatotoxin D-galactosamine (GalN) and lipopoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f95f37f9270422c5de3bd420f20e73f
https://pubmed.ncbi.nlm.nih.gov/8179009
https://pubmed.ncbi.nlm.nih.gov/8179009
Autor:
M L, Schilsky, I, Sternlieb
Publikováno v:
Advances in veterinary science and comparative medicine. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32a0b2e1d713420b9c0c8871cb8421d8
https://pubmed.ncbi.nlm.nih.gov/8273520
https://pubmed.ncbi.nlm.nih.gov/8273520