Zobrazeno 1 - 10
of 49
pro vyhledávání: '"M L, Rocha"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4254 (2024)
Four afatinib derivatives were designed and modeled. These derivatives were compared to the known tyrosine-kinase inhibitors in treating Chronic Myeloid Leukemia, i.e., imatinib and ponatinib. The molecules were evaluated through computational method
Externí odkaz:
https://doaj.org/article/fb230ff8778a452a8bc281206484270b
Autor:
Bruno M. L. Rocha, Gonçalo J. L. Cunha, Pedro Freitas, Pedro M. D. Lopes, Ana C. Santos, Sara Guerreiro, António Tralhão, António Ventosa, Maria J. Andrade, João Abecasis, Carlos Aguiar, Carla Saraiva, Miguel Mendes, António M. Ferreira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract To assess whether a simplified cardiac magnetic resonance (CMR)–derived lung water density (LWD) quantification predicted major events in Heart Failure (HF). Single-centre retrospective study of consecutive HF patients with left ventricula
Externí odkaz:
https://doaj.org/article/c9a17b9f43494454833b680a1322c673
Autor:
Gonçalo J L Cunha, Sérgio Maltês, Bruno M L Rocha, Duarte Nina, Carlos Aguiar, Maria J Andrade, Luís Moreno, Anaí Durazzo, Miguel Mendes, Piergiuseppe Agostoni
Publikováno v:
European Journal of Preventive Cardiology. 30:498-505
Exercise oscillatory ventilation (EOV) is a strong prognostic marker in patients with heart failure (HF) and left ventricular (LV) dysfunction. This phenomenon can be explained through a single quantitative measurement of ventilatory instability, the
Publikováno v:
European Heart Journal - Case Reports. 7
Autor:
Monnic M. L. Rocha, Adagmar Andriolo
Publikováno v:
Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 51, Iss 5, Pp 284-290 (2015)
ABSTRACTIntroduction:Normal renal function is a prerequisite for maintaining the normal balance of calcium and phosphorus. The incidence of 1,25-dihydroxyvitamin D (1,25(OH)2D, or calcitriol) deficiency in renal transplant patients is 50%. The causes
Externí odkaz:
https://doaj.org/article/fb54c0def3ab4f6aa22609844ce3ea6e
Publikováno v:
European Heart Journal - Case Reports. 7
Autor:
Daniel Gomes, Bruno M L Rocha, Jorge Ferreira, Mariana Sousa Paiva, Rita Reis Santos, Marina Raquel Santos, Gonçalo Cunha, Pedro de Araújo Gonçalves, Susana Fevereiro, Marisa Trabulo, Carlos Aguiar, Miguel Sousa-Uva, José Neves, Miguel Mendes
Publikováno v:
Cardiovascular Research. 118
Background ESC guidelines for non-ST elevation acute coronary syndromes (NSTE-ACS) recommend against P2Y12 pre-treatment receptor inhibitors (P2Y12i) in patients undergoing early invasive management (< 24 h). The rationale is, in part, to prevent ble
Autor:
S Maltes, B M L Rocha, G J L Cunha, M S Paiva, A C Vasques, P Freitas, S Guerreiro, L Marta, J Abecasis, R Regina, M J Andrade, C T Aguiar, A Martins, M Mendes
Publikováno v:
European Heart Journal. 43
Background Chemotherapy-induced cardiotoxicity is a serious complication often leading to heart failure. While the left ventricle (LV) has been thoroughly implicated in this process, data is scarce on right ventricular (RV) function following cardiot
Publikováno v:
European Heart Journal - Case Reports. 6
Background Mitral valve prolapse (MVP) is a common valvular heart disease and has often been associated with an increased risk of sudden cardiac death (SCD). This underlines the pressing need for the establishment of consistent tools for arrhythmic r