Zobrazeno 1 - 6 of 6 pro vyhledávání: '"M L, Roantree"'
1
Dipole moment in relation to hydrogen receptor histamine antagonist activity for cimetidine analogs
Autor: R. C. Mitchell, M. L. Roantree, C. R. Ganellin, Rodney C. Young, Graham J. Durant, H. D. Prain, M. J. Graham, John Colin Emmett
Publikováno v: Journal of Medicinal Chemistry. 29:44-49
The activities of a series of H2 receptor histamine antagonists structurally related to cimetidine (1) have been compared to investigate the effect of replacing the cyanoguanidine moiety by other neutral, dipolar groups. Antagonist activity, as measu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ca07ee716692bc3d7a7d0c040d9e181
https://doi.org/10.1021/jm00151a007
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2
Zwitterionic analogs of cimetidine as H2 receptor antagonists
Autor: Z. Tashma, C. R. Ganellin, M. J. Graham, M. L. Roantree, Rodney C. Young, R. C. Mitchell
Publikováno v: Journal of Medicinal Chemistry. 30:1150-1156
A series of analogues of the H2 receptor histamine antagonist cimetidine have been synthesized in which the dipolar cyanoguanidine group has been replaced by a number of zwitterionic moieties. Although none of the compounds is more effective than cim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ef651d87709c5cd9385f51ff99729d
https://doi.org/10.1021/jm00390a006
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3
Dipole moment in relation to H2 receptor histamine antagonist activity for cimetidine analogues
Autor: R C, Young, G J, Durant, J C, Emmett, C R, Ganellin, M J, Graham, R C, Mitchell, H D, Prain, M L, Roantree
Publikováno v: Journal of medicinal chemistry. 29(1)
The activities of a series of H2 receptor histamine antagonists structurally related to cimetidine (1) have been compared to investigate the effect of replacing the cyanoguanidine moiety by other neutral, dipolar groups. Antagonist activity, as measu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b6a05711c658b1875785f095c53cab5
https://pubmed.ncbi.nlm.nih.gov/3941412
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5
ChemInform Abstract: Dipole Moment in Relation to H2Receptor Histamine Antagonist Activity for Cimetidine Analogues
Autor: Graham J. Durant, Rodney C. Young, C. R. Ganellin, M. J. Graham, R. C. Mitchell, M. L. Roantree, H. D. Prain, John Colin Emmett
Publikováno v: Chemischer Informationsdienst. 17
H2-Rezeptor-Histaminantagonisten wie (III)-(VI) werden in uberwiegend literaturbekannter Weise synthetisiert und hinsichtlich ihrer Aktivitat mit Cimetidin (VII) verglichen.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6220679aa3608c6eef56af8f651b508f
https://doi.org/10.1002/chin.198620343
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6
ChemInform Abstract: Zwitterionic Analogues of Cimetidine as H2 Receptor Antagonists
Autor: Z. Tashma, M. L. Roantree, R. C. Mitchell, C. R. Ganellin, Rodney C. Young, M. J. Graham
Publikováno v: ChemInform. 18
A series of analogues of the H2 receptor histamine antagonist cimetidine have been synthesized in which the dipolar cyanoguanidine group has been replaced by a number of zwitterionic moieties. Although none of the compounds is more effective than cim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fc9574c0e9b6a6bb6fdf2b0ecc70864
https://doi.org/10.1002/chin.198750213
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