Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M L, Lipman"'
Publikováno v:
The Journal of Immunology. 157:5231-5239
The glucocorticoids (GCs) dexamethasone (DEX) and prednisolone (PRED), in a concentration-dependent fashion, profoundly inhibit mitogen-induced proliferation of human peripheral blood mononuclear lymphocytes (PBML). This inhibition was specific for G
Publikováno v:
Inflammatory bowel diseases. 1(2)
The histopathology of the mucosal lesions in ulcerative colitis suggests that cellular immune hyperactivity plays a role in the pathogenesis of ulcerative colitis. The role of colonic mucosal cytotoxic lymphocytes in ulcerative colitis is highly cont
Publikováno v:
Journal of the American Society of Nephrology. 6:281-285
Allograft rejection is a T cell-dependent process. It is not known whether rejection is mediated by a limited number of T cell clones or by a polyclonal population of T cells. Several studies attempting to answer this question using molecular techniq
Autor:
Alain Bitton, Mark A. Peppercorn, A C Stevens, Julie E. Spivack, Terry B. Strom, M L Lipman, Gardiner Roddey
Publikováno v:
Inflammatory Bowel Diseases. 1:101-107
The histopathology of the mucosal lesions in ulcerative colitis suggests that cellular immune hyperactivity plays a role in the pathogenesis of ulcerative colitis. The role of colonic mucosal cytotoxic lymphocytes in ulcerative colitis is highly cont
Publikováno v:
The Journal of Immunology. 152:5120-5127
The role of CTL in the immunopathogenesis of acute cellular rejection is controversial. To further define the relationship of activated CTLs to rejection, we analyzed gene expression of three CTL-derived effector molecules in renal allograft biopsies
Autor:
Chander Singaram, Gerd Walz, Donald A. Antonioli, M L Lipman, Aldo Muggia, Bernd Zanker, Terry B. Strom, Mark A. Peppercorn, Christopher Stevens
Publikováno v:
Digestive Diseases and Sciences. 37:818-826
The etiology of ulcerative colitis (UC) and Crohn's disease (CD) remains enigmatic. Infiltrating intestinal macrophages are capable of producing the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1 beta), an
Autor:
M L Lipman, R C Bleackley, Michael E. Shapiro, Seymour Rosen, William E. Harmon, Terry B. Strom, T R McCune, A C Stevens, J H Helderman
Publikováno v:
Transplantation. 53:73-79
Several immune mechanisms are likely to be responsible for renal allograft rejection. The relative importance of delayed-type hypersensitivity versus cytotoxic T lymphocytes is controversial. We analyzed human renal allografts biopsies for intragraft
Publikováno v:
The Journal of Immunology. 146:3523-3527
Glucocorticoids (GCS) inhibit the transcription of multiple activation-associated cytokine genes. By Northern blot analysis now we demonstrate that antiproliferative concentrations of dexamethasone and 6 alpha-methylprednisolone block mitogen-induced
Autor:
Jürgen Strehlau, Wlodzimierz Maslinski, Terry B. Strom, M L Lipman, Michael E. Shapiro, Martha Pavlakis
Publikováno v:
Transplantation. 62:543-545
IL-15, a novel growth factor made by a variety of cells, stimulates T cell proliferation in a fashion similar to IL-2. IL-2 transcripts are not routinely found in rejecting human renal allografts at the time of clinically evident rejection. However,
Autor:
M L, Lipman, D, Panda, H P, Bennett, J E, Henderson, E, Shane, Y, Shen, D, Goltzman, A C, Karaplis
Publikováno v:
The Journal of biological chemistry. 273(22)
Mutations in the PEX gene are responsible for X-linked hypophosphatemic rickets. To gain insight into the role of PEX in normal physiology we have cloned the human full-length cDNA and studied its tissue expression, subcellular localization, and pept