Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M L, Kopka"'
Publikováno v:
Journal of computer-aided molecular design. 11(6)
We report the design of optimal linker geometries for the synthesis of stapled DNA-minor-groove-binding molecules. Netropsin, distamycin, and lexitropsins bind side-by-side to mixed-sequence DNA and offer an opportunity for the design of sequence-rea
Publikováno v:
Journal of molecular biology. 269(5)
The non-self-complementary DNA decamer C-A-A-A-G-A-A-A-A-G/C-T-T-T-T-C-T-T-T-G is a DNA/DNA analogue of a portion of the polypurine tract or PPT, which is a RNA/DNA hybrid that serves as a primer for synthesis of the (+) DNA strand by HIV reverse tra
Publikováno v:
Biopolymers. 44(4)
Sequence-specific polyamides that bind in the minor groove of DNA are attractive candidates for antibiotics, cancer chemotherapeutics, and transcriptional antagonists. This paper reviews the progress of structure-based design of minor-groove-binding
Publikováno v:
The Journal of biological chemistry. 257(24)
A double-helical B-DNA dodecamer has been analyzed by single crystal x-ray diffraction methods and refined independently in four variants: sequence CGCGAATTCGCG at 20 degrees C and at 16 K, and CGCGAATTBrCGCG in 60% methylpentanediol at 20 and at 7 d
Publikováno v:
Nucleic Acids and Molecular Biology ISBN: 9783642465987
Nucleic Acids and Molecular Biology
Nucleic Acids and Molecular Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::424c3c54ec9b5f5536efd1058fe5ed95
https://doi.org/10.1007/978-3-642-46596-3_1
https://doi.org/10.1007/978-3-642-46596-3_1
Publikováno v:
Journal of molecular biology. 163(1)
The crystal structure of the double-helical B-DNA dodecamer of sequence C-G-C-G-A-A-T-T-C-G-C-G has been solved and refined independently in three forms: (1) the parent sequence at room temperature; (2) the same sequence at 16 K; and (3) the 9-bromo
Publikováno v:
Journal of molecular biology. 183(4)
The antitumor antibiotic netropsin has been co-crystallized with a double-helical B-DNA dodecanucleotide of sequence: C-G-C-G-A-A-T-T-BrC-G-C-G, and the structure of the complex has been solved by X-ray diffraction at a resolution of 2.2 A. The struc
Publikováno v:
The Journal of biological chemistry. 242(12)
Publikováno v:
Journal of molecular biology. 45(1)
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