Výsledky vyhledávání - "M L, Jennens"

Akademický článek

Rat GP-3 is a pancreatic lipase with kinetic properties that differ from colipase-dependent pancreatic lipase

Autor: M L Jennens, M E Lowe

Publikováno v: Journal of Lipid Research, Vol 36, Iss 11, Pp 2374-2382 (1995)

The pancreas contains three homologous proteins, colipase-dependent pancreatic lipase (PL) and two recently described pancreatic lipase-related proteins, PLRP1 and PLRP2. Rat (r) PLRP2 was first identified as a zymogen granule membrane protein, GP-3.

Externí odkaz: https://doaj.org/article/27694dfed5944c4782e1b45acd08ca87

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Akademický článek

C-terminal domain of human pancreatic lipase is required for stability and maximal activity but not colipase reactivation.

Autor: M L Jennens, M E Lowe

Publikováno v: Journal of Lipid Research, Vol 36, Iss 5, Pp 1029-1036 (1995)

Fungal lipases and human pancreatic lipase (hPL) share a common tertiary structure termed the alpha/beta hydrolase fold. In contrast, the region C-terminal to the common tertiary structure does not share any common structural features with fungal lip

Externí odkaz: https://doaj.org/article/65ad5fa406b44fb88aa3cb1d989c7607

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C-terminal domain of human pancreatic lipase is required for stability and maximal activity but not colipase reactivation

Autor: Mark E. Lowe, M L Jennens

Publikováno v: Journal of Lipid Research, Vol 36, Iss 5, Pp 1029-1036 (1995)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b05bba2554e41d56b43c807c6446d9
http://www.sciencedirect.com/science/article/pii/S0022227520398606

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Rat pancreatic lipase and two related proteins: enzymatic properties and mRNA expression during development

Autor: Harold F. Sims, R. M. Payne, M L Jennens, Mark E. Lowe

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 266:G914-G921

We report the cDNA sequences of rat colipase, rat pancreatic lipase (rPL), and a rat pancreatic lipase-related protein (rPLRP). Comparison to the human PLRP cDNA suggests that the isolated clone encodes rPLRP-2. Both cDNA and a third cDNA encoding rP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761c6c99fb10f99aeafe978a40a168ef
https://doi.org/10.1152/ajpgi.1994.266.5.g914

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A surface loop covering the active site of human pancreatic lipase influences interfacial activation and lipid binding

Autor: M L, Jennens, M E, Lowe

Publikováno v: The Journal of biological chemistry. 269(41)

The distinguishing feature of lipases is their increased activity at an oil-water interface, termed interfacial activation. X-ray crystallography of lipases suggested a mechanism for interfacial activation by revealing conformational changes in sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e1eb0a85b1460b12515cc2ee6761487
https://pubmed.ncbi.nlm.nih.gov/7929247

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The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family

Autor: M L Jennens, Harold F. Sims, Mark E. Lowe

Publikováno v: Gene. 131(2)

The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205f03ec1eacc4789daed2aba13d80bc
https://pubmed.ncbi.nlm.nih.gov/8406023

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