Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M L, Gubler"'
Publikováno v:
Oncogene. 13(11)
The p53 tumor suppressor gene product is a sequence-specific transcription activator frequently mutated in a variety of human malignancies. Typically, tumor-derived p53 missense mutants are defective in DNA binding and this is likely to result in a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff4a98b8640042c2e7c696641309c2ad
https://pubmed.ncbi.nlm.nih.gov/8957091
https://pubmed.ncbi.nlm.nih.gov/8957091
Publikováno v:
Cancer research. 55(16)
The p53 tumor suppressor is a transcription factor frequently mutated in human malignancies. Tumor-derived p53 missense mutants are defective in sequence-specific DNA binding and fail to activate p53 target genes. mAb PAb421 was shown previously to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff904197a0a475319a833fd5f3d444ac
https://pubmed.ncbi.nlm.nih.gov/7627952
https://pubmed.ncbi.nlm.nih.gov/7627952
Autor:
M L, Gubler, P, Abarzúa
Publikováno v:
BioTechniques. 18(6)
A nonradioactive functional assay was developed to quantitate DNA binding proteins. The assay was designed to allow the use of 96-well microplates for high sample throughput. We show that the assay can measure sequence-specific DNA binding of purifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c0be3f9bc15915de86af54f875d4207
https://pubmed.ncbi.nlm.nih.gov/7546700
https://pubmed.ncbi.nlm.nih.gov/7546700
Autor:
M L, Gubler, M I, Sherman
Publikováno v:
Methods in enzymology. 189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::717c491a9e650e0d2c846a10222cd6d6
https://pubmed.ncbi.nlm.nih.gov/2292968
https://pubmed.ncbi.nlm.nih.gov/2292968
Publikováno v:
The Journal of Cell Biology
Cells from embryonal carcinoma (EC) lines 6050AJ and PCC4.aza 1R differentiate in response to treatment with sodium butyrate as well as retinoic acid (RA) or hexamethylenebisacetamide (HMBA). Murine 6050AJ EC cells exposed to sodium butyrate possess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c2d5a9971ffe4102f8bc70a9bc6f33
https://doi.org/10.1083/jcb.98.2.602
https://doi.org/10.1083/jcb.98.2.602
Autor:
M L, Gubler, M I, Sherman
Publikováno v:
The Journal of biological chemistry. 260(17)
Several embryonal carcinoma (EC) cell lines were tested in culture for their ability to metabolize all-trans-[3H]retinol, all-trans-[3H]retinyl acetate, and all-trans-[3H]retinoic acid. There was little, if any, metabolism of all-trans-retinol to mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6109cc6871a2e1145cc2c1713c6b631
https://pubmed.ncbi.nlm.nih.gov/4019486
https://pubmed.ncbi.nlm.nih.gov/4019486
Publikováno v:
Progress in clinical and biological research. 226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::896525f92a362d22a6b12c2ae5544cad
https://pubmed.ncbi.nlm.nih.gov/3027713
https://pubmed.ncbi.nlm.nih.gov/3027713
Publikováno v:
Cancer research. 48(13)
We have examined the effects of dietary retinoids upon the growth and differentiation of seven embryonal carcinoma lines in mice. The control diet contained 4000 IU/mg retinyl palmitate; the other diets contained 2 x 10(5) IU/mg retinyl palmitate, 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0b7ce6f08c1a7f65458b18cd222dc2f
https://pubmed.ncbi.nlm.nih.gov/3378217
https://pubmed.ncbi.nlm.nih.gov/3378217
Publikováno v:
Ciba Foundation symposium. 113
To study how retinoids promote differentiation and inhibit proliferation of embryonal carcinoma (EC) cells, we have followed their intracellular fate. Retinoic acid (RA) is effectively metabolized to more polar compounds by many EC lines. Unlike RA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af156497199e4ab5a2491be893e6b3c1
https://pubmed.ncbi.nlm.nih.gov/2992894
https://pubmed.ncbi.nlm.nih.gov/2992894
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.