Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M L, Funderburgh"'
Publikováno v:
The Journal of biological chemistry. 274(26)
Mimecan is a proteoglycan expressed by many connective tissues. It was originally isolated in a truncated form as a bone-associated glycoprotein, osteoglycin, and was considered an osteoinductive factor. Recently, we demonstrated that the full-length
Publikováno v:
Investigative ophthalmologyvisual science. 38(6)
Keratan sulfate proteoglycans (KSPGs) of the cornea exhibit a characteristic change in glycosylation resulting from stromal inflammation and scarring. To examine potential roles for these molecules in the pathobiology of the cornea, the authors inves
Publikováno v:
The Journal of biological chemistry. 271(16)
Previous studies showed that the keratan sulfate-containing proteoglycans of bovine corneal stroma contain three unique core proteins designated 37A, 37B, and 25 (Funderburgh, J. L., Funderburgh, M. L., Mann, M. M., and Conrad, G. W. (1991) J. Biol.
Autor:
J L, Funderburgh, M L, Funderburgh, N D, Hevelone, M E, Stech, M J, Justice, C Y, Liu, W W, Kao, B S, Spooner
Publikováno v:
Investigative ophthalmologyvisual science. 36(11)
Lumican is a major proteoglycan of vertebrate cornea. This study characterizes mouse lumican, its molecular form, cDNA sequence, and chromosomal localization.Lumican sequence was determined from cDNA clones selected from a mouse corneal cDNA expressi
Autor:
J L, Funderburgh, M L, Funderburgh, S J, Brown, J P, Vergnes, J R, Hassell, M M, Mann, B S, Spooner
Publikováno v:
The Journal of biological chemistry. 268(16)
Amino acid sequence from tryptic peptides of three different bovine corneal keratan sulfate proteoglycan (KSPG) core proteins (designated 37A, 37B, and 25) showed similarities to the sequence of a chicken KSPG core protein lumican. Bovine lumican cDN
Publikováno v:
The Journal of biological chemistry. 266(36)
A glycoprotein reactive with antibodies against corneal keratan sulfate proteoglycan (KSPG) was purified 300-fold from extracts of bovine aorta using DEAE ion-exchange, gel-filtration, hydrophobic interaction, and reverse-phase chromatographic separa
Publikováno v:
The Journal of biological chemistry. 266(22)
Recent work demonstrates isoforms of bovine corneal keratan sulfate proteoglycan containing structurally unique core proteins of 25 and 37 kDa (Funderburgh, J., and Conrad, G. (1990) J. Biol. Chem. 265, 8297-8303). In the current study, two forms (37
Publikováno v:
Investigative ophthalmologyvisual science. 31(3)
Monoclonal antibody against keratan sulfate (KS) was used for immunofluorescent staining of sections of human corneas from 8 normal eyes, 19 with keratoconus, 4 with pellucid marginal degeneration, 5 with primary macular corneal dystrophy, and 1 with
Publikováno v:
Investigative ophthalmologyvisual science. 27(10)
Thymidine kinase (TK) activity was examined in extracts of TK-deficient cells infected with low passage isolates of herpes simplex virus type 1 (HSV-1) obtained from patients with herpetic keratitis. TK activity induced by the virus, relative phospho