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pro vyhledávání: '"M L, Dustin"'
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
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Autor:
M L, Dustin
Publikováno v:
Journal of clinical immunology. 21(4)
The T cell and antigen-presenting cell communicate to initiate an immune response through formation of an immunological synapse. This specialized cell-cell junction is compartmentalized into adhesion molecule and T cell receptor enriched regions or S
Autor:
K. D. C. Jensen, J. Wienands, A. Shibuya, H. Bohnenberger, H. Kikutani, P. Marrack, E. W. Newell, E. Huseby, S. Tahara-Hanaoka, N. Totsuka, K. Kometani, C. Nakahashi-Oda, J. Scott-Browne, M. S. Kuhns, Kenji Shibuya, N. Anikeeva, K. Dittmann, M. Tokunaga, M. M. Kessels, Y. Sykulev, V. Bremes, J. Kappler, J. B. Huppa, M. L. Dustin, B. F. Lillemeier, K. Rubtsova, M. Hikida, T. Yasui, M. M. Davis, T. Oellerich, F. Wan, H. Hsiao, S. Dai, F. Crawford, M. Engelke, T. Kurosaki, T. Nakano, T. Bock, T. O. Cameron, M. Kadosaki, A. T. Girvin, L. L. Lanier, L. Yin, A. Beal, R. Chen, L. O. Klein, Y. Chien, P. J. Norris, N. Martínez-Martín, K. Sakata-Sogawa, B. Qualmann, T. Saito, K. Neumann, H. Urlaub, T. Yokosuka, T. Yamada, K. C. Garcia, W. W. A. Schamel, E. P. Dopfer, M. Huse, S. Minguet, B. Wollscheid, B. Alarcón, M. J. Lenardo, R. Varma
Publikováno v:
International Immunology. 22:i39-i40
Autor:
J. J. Hogan, L. Beaton, Danelle Eto, Daniel DiToro, E. Kieff, Isharat Yusuf, M. L. Dustin, Hitoshi Kikutani, Joe Craft, Burton E. Barnett, Akemi Sakamoto, R. R. Ramiscal, C. G. Vinuesa, Amanda C. Poholek, Masafumi Arima, T. A. Schwickert, N. K. Verma, Takeshi Tokuhisa, Nobuaki Yoshida, Teruhito Yasui, R. J. Rigby, G. Mosialos, Gabriel D. Victora, T. Nishimura, Charles R. Mackay, D. Yu, Michel C. Nussenzweig, Christopher C. Goodnow, Ayako Inamine, K. Yada, Masahiko Hatano, M. Srivastava, Satoru Tada, Robert J. Johnston, T. Morimoto, M. A. Linterman, Alexander L. Dent, D. Kitayama, Takao Koike, Shane Crotty, Mark J. Smyth
Publikováno v:
International Immunology. 22:ii76-ii77
Autor:
Z M, Ding, J E, Babensee, S I, Simon, H, Lu, J L, Perrard, D C, Bullard, X Y, Dai, S K, Bromley, M L, Dustin, M L, Entman, C W, Smith, C M, Ballantyne
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(9)
To differentiate the unique and overlapping functions of LFA-1 and Mac-1, LFA-1-deficient mice were developed by targeted homologous recombination in embryonic stem cells, and neutrophil function was compared in vitro and in vivo with Mac-1-deficient
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(6)
We examined binding of soluble intercellular adhesion molecule-1 (ICAM-1) dimers and a range of ICAM-1-coated particles to activated T cells. Lymphocyte function-associated antigen-1 (LFA-1) on the surface of activated T cells did not bind soluble IC
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(5)
T cell recognition of foreign Ag/MHC class II complexes is sensitive down to approximately 100 complexes per cell or approximately 0.2 complexes/micron2. To better understand the physical basis of the recognition stage of Ag presentation, we examined
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(5)
Binding of peptides to MHC class II Ag generates ligands for TCR of Th lymphocytes. We have identified a novel class of peptides bound to MHC class II: mannose 6- phosphate (Man-6-P) containing glycopeptides from lysosomal enzymes. These species were
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(9)
We demonstrate complementary differences in the behavior of B lymphoblastoid cells adhering to LFA-1 or its counter-receptor ICAM-1. The interaction of B lymphoblastoid cells with glass-supported planar bilayers bearing LFA-1 or ICAM-1 was observed b
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(4)
Species restrictions in immune cell interactions have been demonstrated both in Ag-specific responses of T lymphocytes and the phenomenon of natural attachment. To determine the possible contribution of adhesion receptors to these restrictions, we ha