Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M L, Bittner"'
Autor:
M. L. Bittner, J. M. Trent, Y. A. Su, M. Ray, Patrick O. Brown, Joseph L. DeRisi, Yi Chen, P. S. Meltzer, Lolita Penland
Publikováno v:
Nature Genetics. 14:457-460
The development and progression of cancer and the experimental reversal of tumorigenicity are accompanied by complex changes in patterns of gene expression. Microarrays of cDNA provide a powerful tool for studying these complex phenomena. The tumorig
Autor:
W, Schulz, M-L, Bittner-Lorenz
Publikováno v:
Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)). 65(11)
Beginning with 1.9.2001 institution-overlapping treatment planning conferences are being carried out for mentally disturbed and handicapped persons, for whom a service based on paragraphs 39, 40 German Social Legislation is applied. In this study we
Autor:
J, Luo, D J, Duggan, Y, Chen, J, Sauvageot, C M, Ewing, M L, Bittner, J M, Trent, W B, Isaacs
Publikováno v:
Cancer research. 61(12)
Critical aspects of the biology and molecular basis for prostate malignancy remain poorly understood. To reveal fundamental differences between benign and malignant growth of prostate cells, we performed gene expression profiling of primary human pro
Autor:
K, Kudoh, M, Ramanna, R, Ravatn, A G, Elkahloun, M L, Bittner, P S, Meltzer, J M, Trent, W S, Dalton, K V, Chin
Publikováno v:
Cancer research. 60(15)
Drug resistance in cancer is a major obstacle to successful chemotherapy. Cancer cells exposed to antitumor drugs may be directly induced to express a subset of genes that could confer resistance, thus allowing some cells to escape killing and form t
Publikováno v:
Molecular carcinogenesis. 28(2)
The development and progression of cancer are believed to be due to multiple genetic alterations resulting in complex changes in expression of many genes. The parental malignant melanoma cell line UACC903 displays anchorage-independent growth, and th
Publikováno v:
Cancer research. 60(4)
Gene amplification is one of the major mechanisms of oncogene activation in tumorigenesis. To facilitate the identification of genes mapping to amplified regions, we have used a technique based on the hybridization of total genomic DNA to cDNA microa
Publikováno v:
Electrophoresis. 20(2)
Currently there are over 1,000,000 human expressed sequence tag (EST) sequences available on the public database, representing perhaps 50-90% of all human genes. The cDNA microarray technique is a recently developed tool that exploits this wealth of
Autor:
R N, Wiltshire, P, Duray, M L, Bittner, T, Visakorpi, P S, Meltzer, R J, Tuthill, L A, Liotta, J M, Trent
Publikováno v:
Cancer research. 55(18)
Human cutaneous malignant melanoma progresses through a series of well defined clinical and histopathological stages. It has been assumed that the neoplastic progression of this disease advances from a common acquired nevus or dysplastic nevus throug
Autor:
X Y, Guan, C B, Cargile, S L, Anzick, F H, Thompson, P S, Meltzer, M L, Bittner, R, Taetle, J R, McGill, J M, Trent
Publikováno v:
Cancer research. 55(15)
DNA sequence amplification contributes to the multistep process of carcinogenesis, and overexpression of amplified genes has been shown to contribute to the malignant phenotype. Cytogenetic analyses of human tumor cells, including ovarian malignancie
Publikováno v:
Journal of Biological Chemistry. 260:10263-10267
Monoclonal antibodies to Escherichia coli recA protein were prepared, characterized, and used as affinity reagents for the purification of recA and recA:somatostatin fusion proteins. The monoclonal antibodies recognize an antigenic determinant or det