Zobrazeno 1 - 10
of 357
pro vyhledávání: '"M Kupfer"'
Autor:
Anne Olazabal-Herrero, Boxue He, Youngho Kwon, Abhishek K. Gupta, Arijit Dutta, Yuxin Huang, Prajwal Boddu, Zhuobin Liang, Fengshan Liang, Yaqun Teng, Li Lan, Xiaoyong Chen, Huadong Pei, Manoj M. Pillai, Patrick Sung, Gary M. Kupfer
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113610- (2024)
Summary: Fanconi anemia (FA) is characterized by congenital abnormalities, bone marrow failure, and cancer susceptibility. The central FA protein complex FANCI/FANCD2 (ID2) is activated by monoubiquitination and recruits DNA repair proteins for inter
Externí odkaz:
https://doaj.org/article/bc92b447e5014f469f04a528e03fd245
Autor:
Sharon Noy-Lotan, Orly Dgany, Nathaly Marcoux, Ayelet Atkins, Gary M. Kupfer, Linette Bosques, Christine Gottschalk, Orna Steinberg-Shemer, Benny Motro, Hannah Tamary
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Congenital dyserythropoietic anemia type I (CDA I) is an autosomal recessive disease characterized by moderate to severe macrocytic anemia and pathognomonic morphologic abnormalities of the erythroid precursors, including spongy heterochromatin. The
Externí odkaz:
https://doaj.org/article/de2db599c3204c6095f47339336c7633
Autor:
Fengshan Liang, Adam S. Miller, Simonne Longerich, Caroline Tang, David Maranon, Elizabeth A. Williamson, Robert Hromas, Claudia Wiese, Gary M. Kupfer, Patrick Sung
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
In the Fanconi anemia pathway, deubiquitination of FANCD2 is a fundamental regulatory step. Here, the authors have developed a set of biochemical tools to reconstitute FANCD2 deubiquitination by recombinant USP1-UAF1-RAD51AP1 and reveal critical mech
Externí odkaz:
https://doaj.org/article/c6be56908081470bb7bc5319e965b081
Autor:
Neil Pathak, BS, Alana M. Munger, MD, Ahmad Charifa, MD, William B. Laskin, MD, Emily Bisson, APRN, CPNP, Gary M. Kupfer, MD, Lee E. Rubin, MD
Publikováno v:
Arthroplasty Today, Vol 6, Iss 1, Pp 52-58.e1 (2020)
Hemophilia A is a rare genetic disorder involving a deficiency of clotting factor VIII. Coagulation factor replacement therapy has prolonged the life expectancy of patients with hemophilia, but recurrent hemarthrosis of major joints is often a common
Externí odkaz:
https://doaj.org/article/c35494b2f541495d88c935d63d2eedad
Autor:
Hilary A. Uyhelji, Doris M. Kupfer, Vicky L. White, Melinda L. Jackson, Hans P. A. Van Dongen, Dennis M. Burian
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-17 (2018)
Abstract Background Although sleep deprivation is associated with neurobehavioral impairment that may underlie significant risks to performance and safety, there is no reliable biomarker test to detect dangerous levels of impairment from sleep loss i
Externí odkaz:
https://doaj.org/article/87b5094048414ecdb2f05b85c0dfd5c1
Autor:
Susree Modepalli, Sandra Martinez-Morilla, Srividhya Venkatesan, James Fasano, Katerina Paulsen, Dirk Görlich, Shilpa Hattangadi, Gary M. Kupfer
Publikováno v:
Experimental Hematology. 114:22-32
Erythroid nuclear condensation is a complex process in which compaction to one-tenth its original size occurs in an active nucleus simultaneously undergoing transcription and cell division. We previously found that the nuclear exportin Exportin7 (Xpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c916cde852c0308654a635d15bcb3d
https://doi.org/10.1016/j.exphem.2022.08.001
https://doi.org/10.1016/j.exphem.2022.08.001
Autor:
Zora R. Rogers, Taizo A. Nakano, Timothy S. Olson, Alison A. Bertuch, Winfred Wang, Alfred Gillio, Thomas D. Coates, Anjulika Chawla, Paul Castillo, Peter Kurre, Christopher Gamper, Carolyn M. Bennett, Sarita Joshi, Amy E. Geddis, Jessica Boklan, Grzegorz Nalepa, Jennifer A. Rothman, James N. Huang, Gary M. Kupfer, Michaela Cada, Bertil Glader, Kelly J. Walkovich, Alexis A. Thompson, Rabi Hanna, Adrianna Vlachos, Maggie Malsch, Edie A. Weller, David A. Williams, Akiko Shimamura
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Quality of response to immunosuppressive therapy and long-term outcomes for pediatric severe aplastic anemia remain incompletely characterized. Contemporary evidence to inform treatment of relapsed or refractory severe aplastic anemia for pediatric p
Externí odkaz:
https://doaj.org/article/e30ee0ec051d4c8a8105c5d827063f09
Autor:
Hadara L Norowitz, Timothy Morello, Hadassah M Kupfer, Stephan A Kohlhoff, Tamar A Smith-Norowitz
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212777 (2019)
This study aims to assess prospectively whether there is an association between frequencies of upper respiratory tract infections (URTI) or asthma in early childhood and failed otoacoustic emission (OAE) screenings later in life. There are no clear r
Externí odkaz:
https://doaj.org/article/0a49a33ec17943c990dccf16b54a3db5
Autor:
M Richards, D Mahajan, T Simon, M Kupfer, A Rajan, K Herrmann, J D Rogers, J Garner, S Pokorney
Publikováno v:
Europace. 25
Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Boston Scientific Corporation Background The LUX-Dx PERFORM Study is designed to evaluate safety and performance of the LUX-Dx Insertable Cardiac Monitor (ICM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d16a2139cee3a343ef9be98a646b4662
https://doi.org/10.1093/europace/euad122.612
https://doi.org/10.1093/europace/euad122.612
Supplement 2B from Human T-Cell Leukemia Virus I Tax Protein Sensitizes p53-Mutant Cells to DNA Damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c7d0c9858e62d4aa72ec34c4333d66
https://doi.org/10.1158/0008-5472.22371588
https://doi.org/10.1158/0008-5472.22371588
