Zobrazeno 1 - 10
of 202
pro vyhledávání: '"M Kiyoki"'
Publikováno v:
Calcified Tissue International. 63:143-147
We compared the cytotoxic effects of alendronate (ALN) and incadronate (YM175) on isolated rabbit osteoclasts in vitro and on rats in vivo. In the in vitro experiment, each bisphosphonate was added to the culture of isolated osteoclasts at the final
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b7320016ab708b4a789b097cdb726c
https://doi.org/10.1007/s002239900505
https://doi.org/10.1007/s002239900505
Autor:
I. Nakamura, M. Kiyoki, K. Shiobara, Y. Nishijima, T. Ohta, M. Shimizu, T. Takehara, R. Nemoto
Publikováno v:
BJU International. 80:274-280
Objective To assess serum pyridinoline (Py) and deoxypyridinoline (dPy), using a new high-performance liquid chromatography (HPLC) method, as a serum marker to determine the incidence of metastatic bone disease in an animal model and in the monitorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3fac298490f8e56c75a754a3b8a491
https://doi.org/10.1046/j.1464-410x.1997.00237.x
https://doi.org/10.1046/j.1464-410x.1997.00237.x
Publikováno v:
Advanced Drug Delivery Reviews. 20:181-187
Prostacyclin is one of the most potent vasoactive autacoids, and is now clinically used as an anti-platelet agent, but with limited indications due to its chemical instability, as well as side effects. A chemically stable prostacyclin derivative (Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8266b83b8c30dac4bf1bb0c56050a340
https://doi.org/10.1016/0169-409x(96)00006-3
https://doi.org/10.1016/0169-409x(96)00006-3
Publikováno v:
Endocrinology. 137:2586-2592
In normal rats given alendronate (0.01-6.25 mg/kg) or elcatonin (synthetic eel calcitonin; 0.32-8.0 U/kg), changes in urinary calcium (Ca), pyridinoline (Pyr), and deoxypyridinoline (D-Pyr) excretion during the hypocalcemic response were assessed. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de94f9c655452112916598399b965a9
https://doi.org/10.1210/endo.137.6.8641213
https://doi.org/10.1210/endo.137.6.8641213
Publikováno v:
Dermatology. 192:233-238
Background: The 1,24(R)(OH)2D3 (tacalcitol) ointment (2 μg/g) is available commercially as an antipsoriatic drug in Japan, but the cream preparation of tacalci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6539cd1ac218a2a71ac8e2cde6c913e3
https://doi.org/10.1159/000246373
https://doi.org/10.1159/000246373
Publikováno v:
Bone. 16:235-245
Alendronate is an aminobisphosphonate that acts as a potent inhibitor of osteoclastic bone resorption. To understand the mechanism of action of alendronate in vivo, in this study we investigated the relationship between distribution of [14C]-alendron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4cdc6341d39e273c69192d17895844b
https://doi.org/10.1016/8756-3282(94)00035-x
https://doi.org/10.1016/8756-3282(94)00035-x
Autor:
H Honda, M Kiyoki, T Nakamoto, R Hasegawa, S Jindai, H. Eguchi, T Kubota, M Shiraki, T Yamaji, K. Hosoda
Publikováno v:
Clinical Chemistry. 38:2233-2238
To overcome the problems of limited-region specificity associated with conventional radioimmunoassay (RIA), we developed a sandwich enzyme immunoassay (EIA) for intact human osteocalcin (hOC). For this EIA we used antibodies to the N- and C-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c298902f6fc25f722dd7d08221f154d8
https://doi.org/10.1093/clinchem/38.11.2233
https://doi.org/10.1093/clinchem/38.11.2233
Publikováno v:
Skin pharmacology and applied skin physiology. 14(4)
The human epidermal keratinocyte cell line K-TL-1, developed from a benign epidermal tumor, was cultured in the presence of the synthetic vitamin D3 analogue tacalcitol [1alpha,24(R)-dihydroxyvitamin D3] to assess the effects on the production of ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ce6355c7efcfdd6696863a90886c382
https://pubmed.ncbi.nlm.nih.gov/11464105
https://pubmed.ncbi.nlm.nih.gov/11464105
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(2)
We evaluated the potency of truncated secretory leukoprotease inhibitor (truncated SLPI) in a human sputum elastase (HSE)-induced lung injury model and in a specific neutrophil-mediated acute lung injury model in hamsters. Intratracheal administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9378058a339a9217e6e320c35b2beed8
https://pubmed.ncbi.nlm.nih.gov/9262369
https://pubmed.ncbi.nlm.nih.gov/9262369
Autor:
Toshitaka Nakamura, Y. Tsukamoto, H. Eguchi, Y. Azuma, K. Hosoda, M. Arita, M. Kiyoki, T. Ohta
Publikováno v:
Calcified tissue international. 59(4)
We developed a sandwich enzyme immunoassay system for intact rat osteocalcin to improve the region specificity for the detection of this molecule. We synthesized two peptides of N-terminal 20 residues and C-terminal 10 residues of rat osteocalcin. Af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e85fa0621fa2ec09d007b2af618ae1c
https://pubmed.ncbi.nlm.nih.gov/8781053
https://pubmed.ncbi.nlm.nih.gov/8781053