Cumulative Radiation Exposure and Lifetime Cancer Risk in Patients With Tetralogy of Fallot Requiring Early Intervention

Autor: Jeannette R. Wong-Siegel, MD, MPH, Andrew C. Glatz, MD, MSCE, Courtney McCracken, PhD, Choonsik Lee, PhD, Cari M. Kitahara, PhD, Lene H.S. Veiga, PhD, Yun Zhang, PhD, Bryan H. Goldstein, MD, Christopher J. Petit, MD, Athar M. Qureshi, MD, George T. Nicholson, III, MD, Mark A. Law, MD, Jeffery Meadows, MD, Shabana Shahanavaz, MD, Michael L. O’Byrne, MD, MSCE, Sarosh P. Batlivala, MD, Joelle Pettus, MPH, MS, Asaad Beshish, MD, Christopher E. Mascio, MD, Jennifer C. Romano, MD, Kathyrn O. Stack, MD, Ivor Asztalos, MD, MSCE, Tacy E. Downing, MD, Jeffrey D. Zampi, MD

Publikováno v: JACC: Advances, Vol 3, Iss 10, Pp 101239- (2024)

Background: Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention, utilizing either a staged repair (SR) or primary repair (PR) approach. They are exposed to several sources of low-dose ionizing radiation, which

Externí odkaz: https://doaj.org/article/8ee184a853cb46dc91acd5b9dd1bfd5b

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry

Autor: Stefanie H. Mueller, Alvina G. Lai, Maria Valkovskaya, Kyriaki Michailidou, Manjeet K. Bolla, Qin Wang, Joe Dennis, Michael Lush, Zomoruda Abu-Ful, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Thais Baert, Laura E. Beane Freeman, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Bernardo Bonanni, Hermann Brenner, Sara Y. Brucker, Saundra S. Buys, Jose E. Castelao, Tsun L. Chan, Jenny Chang-Claude, Stephen J. Chanock, Ji-Yeob Choi, Wendy K. Chung, NBCS Collaborators, Sarah V. Colonna, CTS Consortium, Sten Cornelissen, Fergus J. Couch, Kamila Czene, Mary B. Daly, Peter Devilee, Thilo Dörk, Laure Dossus, Miriam Dwek, Diana M. Eccles, Arif B. Ekici, A. Heather Eliassen, Christoph Engel, D. Gareth Evans, Peter A. Fasching, Olivia Fletcher, Henrik Flyger, Manuela Gago-Dominguez, Yu-Tang Gao, Montserrat García-Closas, José A. García-Sáenz, Jeanine Genkinger, Aleksandra Gentry-Maharaj, Felix Grassmann, Pascal Guénel, Melanie Gündert, Lothar Haeberle, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Elaine F. Harkness, Patricia A. Harrington, Jaana M. Hartikainen, Mikael Hartman, Alexander Hein, Weang-Kee Ho, Maartje J. Hooning, Reiner Hoppe, John L. Hopper, Richard S. Houlston, Anthony Howell, David J. Hunter, Dezheng Huo, ABCTB Investigators, Hidemi Ito, Motoki Iwasaki, Anna Jakubowska, Wolfgang Janni, Esther M. John, Michael E. Jones, Audrey Jung, Rudolf Kaaks, Daehee Kang, Elza K. Khusnutdinova, Sung-Won Kim, Cari M. Kitahara, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Katerina Kubelka-Sabit, Allison W. Kurian, Ava Kwong, James V. Lacey, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Martha Linet, Wing-Yee Lo, Jirong Long, Artitaya Lophatananon, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Keitaro Matsuo, Dimitrios Mavroudis, Usha Menon, Kenneth Muir, Rachel A. Murphy, Heli Nevanlinna, William G. Newman, Dieter Niederacher, Katie M. O’Brien, Nadia Obi, Kenneth Offit, Olufunmilayo I. Olopade, Andrew F. Olshan, Håkan Olsson, Sue K. Park, Alpa V. Patel, Achal Patel, Charles M. Perou, Julian Peto, Paul D. P. Pharoah, Dijana Plaseska-Karanfilska, Nadege Presneau, Brigitte Rack, Paolo Radice, Dhanya Ramachandran, Muhammad U. Rashid, Gad Rennert, Atocha Romero, Kathryn J. Ruddy, Matthias Ruebner, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Marjanka K. Schmidt, Rita K. Schmutzler, Michael O. Schneider, Christopher Scott, Mitul Shah, Priyanka Sharma, Chen-Yang Shen, Xiao-Ou Shu, Jacques Simard, Harald Surowy, Rulla M. Tamimi, William J. Tapper, Jack A. Taylor, Soo Hwang Teo, Lauren R. Teras, Amanda E. Toland, Rob A. E. M. Tollenaar, Diana Torres, Gabriela Torres-Mejía, Melissa A. Troester, Thérèse Truong, Celine M. Vachon, Joseph Vijai, Clarice R. Weinberg, Camilla Wendt, Robert Winqvist, Alicja Wolk, Anna H. Wu, Taiki Yamaji, Xiaohong R. Yang, Jyh-Cherng Yu, Wei Zheng, Argyrios Ziogas, Elad Ziv, Alison M. Dunning, Douglas F. Easton, Harry Hemingway, Ute Hamann, Karoline B. Kuchenbaecker

Publikováno v: Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)

Abstract Background Low-frequency variants play an important role in breast cancer (BC) susceptibility. Gene-based methods can increase power by combining multiple variants in the same gene and help identify target genes. Methods We evaluated the pot

Externí odkaz: https://doaj.org/article/44abb13c9f464a339579d4ae653343e9

Endogenous sex steroid hormones and risk of liver cancer among US men: Results from the Liver Cancer Pooling Project

Autor: Zeni Wu, Jessica L. Petrick, Andrea A. Florio, Chantal Guillemette, Laura E. Beane Freeman, Julie E. Buring, Gary Bradwin, Patrick Caron, Yu Chen, A. Heather Eliassen, Lawrence S. Engel, Neal D. Freedman, J. Michael Gaziano, Edward L. Giovannuci, Jonathan N. Hofmann, Wen-Yi Huang, Victoria A. Kirsh, Cari M. Kitahara, Jill Koshiol, I-Min Lee, Linda M. Liao, Christina C. Newton, Julie R. Palmer, Mark P. Purdue, Thomas E. Rohan, Lynn Rosenberg, Howard D. Sesso, Rashmi Sinha, Meir J. Stampfer, Caroline Y. Um, Stephen K. Van Den Eeden, Kala Visvanathan, Jean Wactawski-Wende, Anne Zeleniuch-Jacquotte, Xuehong Zhang, Barry I. Graubard, Peter T. Campbell, Katherine A. McGlynn

Publikováno v: JHEP Reports, Vol 5, Iss 7, Pp 100742- (2023)

Background & Aims: Incidence rates of liver cancer in most populations are two to three times higher among men than women. The higher rates among men have led to the suggestion that androgens are related to increased risk whereas oestrogens are relat

Externí odkaz: https://doaj.org/article/9ea728b893a84b6ead80ea0343ea52b6

Low-dose ionizing radiation exposure and risk of leukemia: results from 1950–1995 Chinese medical X-ray workers’ cohort study and meta-analysis

Autor: Yeqing Gu, Jinhan Wang, Yan Wang, Chang Xu, Yang Liu, Liqing Du, Qin Wang, Kaihua Ji, Ningning He, Manman Zhang, Huijuan Song, Xiaohui Sun, Jixian Wang, Cari M. Kitahara, Amy Berrington de Gonzalez, Kaijun Niu, Qiang Liu

Publikováno v: Journal of the National Cancer Center, Vol 2, Iss 2, Pp 90-97 (2022)

Background: It has been well-established that acute radiation exposures increase the risk of leukemia. However, it is still unknown whether these leukemia risk estimates could be extrapolated to occupational populations who receive repeated low-dose

Externí odkaz: https://doaj.org/article/62dbcc5cca4645638edf5cc630bb8946

Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Autor: Xiaoliang Wang, Pooja Middha Kapoor, Paul L. Auer, Joe Dennis, Alison M. Dunning, Qin Wang, Michael Lush, Kyriaki Michailidou, Manjeet K. Bolla, Kristan J. Aronson, Rachel A. Murphy, Angela Brooks-Wilson, Derrick G. Lee, Emilie Cordina-Duverger, Pascal Guénel, Thérèse Truong, Claire Mulot, Lauren R. Teras, Alpa V. Patel, Laure Dossus, Rudolf Kaaks, Reiner Hoppe, Wing-Yee Lo, Thomas Brüning, Ute Hamann, Kamila Czene, Marike Gabrielson, Per Hall, Mikael Eriksson, Audrey Jung, Heiko Becher, Fergus J. Couch, Nicole L. Larson, Janet E. Olson, Kathryn J. Ruddy, Graham G. Giles, Robert J. MacInnis, Melissa C. Southey, Loic Le Marchand, Lynne R. Wilkens, Christopher A. Haiman, Håkan Olsson, Annelie Augustinsson, Ute Krüger, Philippe Wagner, Christopher Scott, Stacey J. Winham, Celine M. Vachon, Charles M. Perou, Andrew F. Olshan, Melissa A. Troester, David J. Hunter, Heather A. Eliassen, Rulla M. Tamimi, Kristen Brantley, Irene L. Andrulis, Jonine Figueroa, Stephen J. Chanock, Thomas U. Ahearn, Montserrat García-Closas, Gareth D. Evans, William G. Newman, Elke M. van Veen, Anthony Howell, Alicja Wolk, Niclas Håkansson, Hoda Anton-Culver, Argyrios Ziogas, Michael E. Jones, Nick Orr, Minouk J. Schoemaker, Anthony J. Swerdlow, Cari M. Kitahara, Martha Linet, Ross L. Prentice, Douglas F. Easton, Roger L. Milne, Peter Kraft, Jenny Chang-Claude, Sara Lindström

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. We conducted a genome-wide interaction analysis

Externí odkaz: https://doaj.org/article/ea4ad649f9fc4517a57ce808b5aa347d