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Autor:
Ann Alcasid, John M. Kelton, Jeffrey Zhang, Loretta J. Nastoupil, Nitin Kaila, Jocelyn Courville, Pilar Nava-Parada
Publikováno v:
Biodrugs
Background Infusion-related reactions (IRRs) are the most common adverse event (AE) associated with infusion of rituximab, an anti-CD20 monoclonal antibody. Objective Our objective was to evaluate the impact of dosing/infusion patterns and certain ba
Autor:
Kelley D. Mayden, DNP, APRN-FNP, AOCNP, John M. Kelton, PharmD, Joanne C. Ryan, PhD, RN, Ali McBride, PharmD, MS, BCPS
Publikováno v:
Journal of the advanced practitioner in oncology. 13(4)
In oncology practices across the United States, biosimilars—highly similar versions of licensed, innovator (reference) biological medicines—are currently emerging as more affordable therapeutic options. Only after a rigorous product development p
Autor:
Kshama R. Mehta, Catherine P. Jayapandian, Alessia Fornoni, John R. Sedor, Sangeeta Hingorani, Barry I. Freedman, M. Bray, M. Schachere, Christine B. Sethna, L. Barisoni, A. Cooper, Matthias Kretzler, Miroslav Sekulic, Anne Froment, Lawrence A. Greenbaum, J. Blake, Jeffrey B. Kopp, M. Toledo, Yijiang Chen, J. Lalli, Richard A. Lafayette, M. Romano, Duncan B. Johnstone, Katherine R. Tuttle, Katherine MacRae Dell, Kamal Sambandam, Matthew B. Palmer, Marie C. Hogan, J. LaVigne, Frederick J. Kaskel, E. Lim, M. Rogers, Z. Wang, J. Negrey, S. Boynton, Fernando C. Fervenza, Deb Gipson, Vimal K. Derebail, Anant Madabhushi, Sharon G. Adler, Stephen M. Hewitt, Jen Jar Lin, Cynthia C. Nast, John H. Stroger, Clarissa A. Cassol, S. Grubbs, Laura Barisoni, Kevin E.C. Meyers, C. Kang, Jeffrey B. Hodgin, Paula Toro, Ambarish M. Athavale, Frank Modersitzki, Mathew Itteera, Olga Zhdanova, John C. Lieske, Heather N. Reich, G B Appel, John F. O’Toole, Howard Trachtman, S. Quinn-Boyle, Andrew Janowczyk, Suzanne Vento, Alicia M. Neu, Vladimir Chernitskiy, A. Jefferson, M. Kelton, Dan Cattran, Crystal A. Gadegbeku, P. Flynn, N. Kumar, Krishna Kallem, C. Bidot, Michelle Hladunewich, Keisha L. Gibson, Kevin V. Lemley, J. LaPage, A. Garrett, Lawrence B. Holzman, A. Williams, Tarak Srivastava, P. Ling, Jarcy Zee, K. Laurent, Chia-shi Wang
Publikováno v:
Kidney International. 99:86-101
The application of deep learning for automated segmentation (delineation of boundaries) of histologic primitives (structures) from whole slide images can facilitate the establishment of novel protocols for kidney biopsy assessment. Here, we developed
Autor:
Ahmed Shelbaya, Jose Mj Alvir, Jingyan Yang, Martine C. Maculaitis, John M. Kelton, Jeffrey Thompson
Publikováno v:
Future oncology (London, England). 17(30)
Aim: To describe treatment patterns and patient and provider characteristics associated with the recently introduced biosimilar rituximab-pvvr. Methods: This retrospective analysis included adult patients with one or more claims for rituximab-pvvr, w
Autor:
Jingyan Yang, Basit Iqbal Chaudhry, Andrew Yue, John M. Kelton, Ahmed Shelbaya, Lisa Tran, Meng Li
Publikováno v:
Journal of Clinical Oncology. 40:e18836-e18836
e18836 Background: Oncology biosimilars may play an important role in managing risk for providers participating in value-based payment (VBP) models. The impact of biosimilar substitution on risk to providers remains unclear, as prior researchers have
Autor:
Jeffrey B. Hodgin, Laura H. Mariani, Jarcy Zee, Qian Liu, Abigail R. Smith, Sean Eddy, John Hartman, Habib Hamidi, Joseph P. Gaut, Matthew B. Palmer, Cynthia C. Nast, Anthony Chang, Stephen Hewitt, Brenda W. Gillespie, Matthias Kretzler, Lawrence B. Holzman, Laura Barisoni, K. Dell, J. Sedor, M. Schachere, J. Negrey, K. Lemley, E. Lim, T. Srivastava, A. Garrett, C. Sethna, K. Laurent, P. Canetta, A. Pradhan, L. Greenbaum, C. Wang, C. Kang, S. Adler, J. LaPage, A. Athavale, M. Itteera, M. Atkinson, S. Boynton, F. Fervenza, M. Hogan, J. Lieske, V. Chernitskiy, F. Kaskel, M. Ross, P. Flynn, J. Kopp, J. Blake, H. Trachtman, O. Zhdanova, F. Modersitzki, S. Vento, M. Bray, M. Kelton, A. Cooper, R. Lafayette, K. Mehta, C. Gadegbeku, S. Quinn-Boyle, M. Hladunewich, H. Reich, P. Ling, M. Romano, A. Fornoni, C. Bidot, M. Kretzler, D. Gipson, A. Williams, J. LaVigne, V. Derebail, K. Gibson, E. Cole, J. Ormond-Foster, L. Holzman, K. Meyers, K. Kallem, A. Swenson, K. Sambandam, Z. Wang, M. Rogers, A. Jefferson, S. Hingorani, K. Tuttle, J.J. Lin, L. Barisoni, J. Bixler, H. Desmond, S. Eddy, D. Fermin, B. Gillespie, V. Kurtz, M. Larkina, J. Lavigne, S. Li, C.C. Lienczewski, J. Liu, T. Mainieri, L. Mariani, M. Sampson, A. Smith, J. Zee, Carmen Avila-Casado, Serena Bagnasco, Joseph Gaut, Jeff Hodgin, Kevin Lemley, Laura Mariani, Matthew Palmer, Avi Rosenberg, Virginie Royal, David Thomas, Cynthia Nast
Publikováno v:
American Journal of Kidney Diseases. 79:807-819.e1
Rationale & Objective The current classification system for focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) does not fully capture the complex structural changes in kidney biopsies, nor the clinical and molecular heterogene
Autor:
Mark Andrew Lewis, Lindsay Stansfield, John M. Kelton, Michelle L. Edwards, Christopher Hanyoung Lieu
Publikováno v:
Journal of Clinical Oncology. 40:70-70
70 Background: In the US, pts living in rural areas have higher CRC mortality rates than urban areas. Clinical guidelines recommend testing for BRAF and RAS mutations and deficient mismatch repair/microsatellite instability in pts with mCRC. However,
Autor:
Diana T. Amari, John M. Kelton, Anup Abraham, Rebecca Levin, Michelle L. Edwards, Maria Cecilia Vieira
Publikováno v:
Journal of Clinical Oncology. 39:e18778-e18778
e18778 Background: BRAF mutations are estimated to occur in up to 10% of people with colorectal cancer, 45% with melanoma, and 2-4% with NSCLC and generally represent a poor prognosis for these patients. The National Comprehensive Cancer Network (NCC
Autor:
Philip M Bath, Polly Scutt, Craig S Anderson, Jason P Appleton, Evind Berge, Lesley Cala, Mark Dixon, Timothy M England, Peter J Godolphin, Diane Havard, Lee Haywood, Trish Hepburn, Kailash Krishnan, Grant Mair, Alan A Montgomery, Keith Muir, Stephen J Phillips, Stuart Pocock, John Potter, Chris Price, Marc Randall, Thompson G Robinson, Christine Roffe, Peter M Rothwell, Else C Sandset, Nerses Sanossian, Jeffrey L Saver, Angela Shone, A Niroshan Siriwardena, Joanna M Wardlaw, Lisa J Woodhouse, Graham Venables, Nikola Sprigg, Pierre Amarenco, Shannon Amoils, Malcolm Jarvis, Peter Sandercock, Kjell Asplund, Colin Baigent, Sandeep Ankolekar, Harriet Howard, Christopher Lysons, Gemma Walker, Hayley Gregory, James Kirby, Jennifer Smithson, Joanne Keeling, Nadia Frowd, Robert Gray, Richard Dooley, Wim Clarke, Patricia Robinson, Zhe Kang Law, Sheila Hodgson, Adam Millington, Eleni Sakka, David Buchanan, Jeb Palmer, D Shaw, H Cobb, R Johnson, T Payne, R Spaight, A Spaight, M A Sajid, A Whileman, E Hall, H Cripps, J Toms, R Gascoyne, S Wright, M Cooper, A Palfreman, A Rajapakse, I Wynter, K Musarrat, A Mistri, C Patel, C Stephens, S Khan, S Patras, M Soliman, A Elmarimi, C Hewitt, E Watson, I Wahishi, J Hindle, L Perkin, M Wills, S Arif, S Leach, S Butler, D O'Kane, C Smith, J O'Callaghan, W Sunman, A Buck, B Jackson, C Richardson, G Wilkes, J Clarke, L Ryan, O Matias, D Mangion, A Hardwick, C Constantin, I Thomas, K Netherton, S Markova, A Hedstrom, B Rushton, C Hyde, J Scott, M Blair, M Maddula, R Donnelly, S Keane, S Johnson, H McKenzie, A Banerjee, D Hutchinson, H Goodhand, J Hill, K Mellows, M Cheeseman, V McTaggart, T Foster, L Prothero, P Saksena, A O'Kelly, H Wyllie, C Hacon, H Nutt, J North, K Goffin, J Potter, A Wiltshire, G Ravenhill, K Metcalf, L Ford, M Langley, W Davison, S Subramonian, F Magezi, I Obi, N Temple, N Butterworth-Cowin, P Oqwusu-Agyei, A F M Azim, A Nicolson, J Imam, J White, L Wood, R Fothergill, N Thompson, J Lazarus, H Werts, L Sztriha, C Ho, E McKenzie, E Owoyele, J Lim, J Aeron-Thomas, M Dockey, N Sylvester, P Rao, B M Bloom, E Erumere, G Norman, I Skene, L Cuenoud, L Howaniec, O Boulton, P Daboo, R Michael, S Al-Saadi, T Harrison, H Syed, L Argandona, S Amiani, R Perry, A Ashton, A Banaras, C Hogan, C Watchurst, E Elliott, N Francia, N Oji, R Erande, S Obarey, S Feerick, S Tshuma, E England, H Pocock, K Poole, S Manchanda, I Burn, S Dayal, K McNee, M Robinson, R Hancock, A South, C Holmes, A Steele, L B Guthrie, M Oborn, A Mohd Nor, B Hyams, C Eglinton, D Waugh, E Cann, N Wilmhurst, S Piesley, S Shave, D Dutta, M Obeid, D Ward, J Turfrey, J Glass, K Bowstead, L Hill, P Brown, S Beames, S O'Connell, V Hughes, R Whiting, J Gagg, M Hussain, M Harvey, D Karunatilake, B Pusuluri, A Witcher, C Pawley, J Allen, J Foot, J Rowe, C Lane, S Ragab, B Wadams, J Dube, B Jupp, A Ljubez, C Bagnall, G Hann, L Tucker, M Kelton, S Orr, F Harrington, A James, A Lydon, G Courtauld, K Bond, L Lucas, T Nisbett, J Kubie, A Bowring, G Jennings, K Thorpe, N Mason, S Keenan, L Gbadomishi, D Howcroft, H Newton, J Choulerton, J Avis, L Shaw, P Paterson, P Kaye, S Hierons, S Lucas, P Clatworthy, B Faulkner, L Rannigan, R Worner, B Bhaskaran, A Saulat, H Bearne, J Garfield-Smith, K Horan, P Fitzell, S Szabo, M Haley, D Simmons, D Cotterill, G Saunders, H Dymond, S Beech, K Rashed, A Tanate, C Buckley, D Wood, L Matthews, S Board, T Pitt-Kirby, N Rees, C Convery, P Jones, C Bryant, H Tench, M Dixon, R Loosley, S Coetzee, S Jones, T Sims, M Krishnan, C Davies, L Quinn, L Connor, M Wani, S Storton, S Treadwell, T Anjum, C Somashekar, A Chandler, C Triscott, L Bevan, M Sander, S Buckle, W Sayed, K Andrews, L Hughes, R Hughes, M Ward, A Pretty, A Rosser, B Davidson, G Price, I Gunson, J Lumley-Holmes, J Miller, M Larden, M Jhamat, P Horwood, R Boldy, C Jenkins, F Price, M Harrison, T Martin, N Ahmad, A Willberry, A Stevens, K Fotherby, A Barry, A Remegoso, F Alipio, H Maquire, J Hiden, K Finney, R Varquez, S Ispoglou, A Hayes, D Gull, R Evans, E Epstein, S Hurdowar, J Crossley, J Miles, K Hird, R Pilbery, C Patterson, H Ramadan, K Stewart, O Quinn, R Bellfield, S Macquire, W Gaba, A Nair, A Wilson, C Hawksworth, I Alam, J Greig, P Gomes, P Rana, Z Ahmed, P Anderston, A Neal, D Walstow, R Fong, S Brotheridge, A Bwalya, A Gillespie, C Midgley, C Hare, H Lyon, L Stephenson, M Broome, R Worton, S Jackson, R Rayessa, A Abdul-Hamid, C Naylor, E Clarkson, A Hassan, E Veraque, L Finch, L Makawa, M Carpenter, P Datta, A Needle, L Jackson, H J Brooke, J Ball, T Lowry, S Punnoose, R Walker, V Murray, A Ali, C Kamara, C Doyle, E Richards, J Howe, K Dakin, K Harkness, R Lindert, P Wanklyn, P Willcoxson, P Clark-Brown, R Mir
Publikováno v:
2019, ' Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2) : An ambulance-based, randomised, sham-controlled, blinded, phase 3 trial ', The Lancet, vol. 393, no. 10175, pp. 1009-1020 . https://doi.org/10.1016/S0140-6736(19)30194-1
Background: High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ultra-acute stroke remains unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe070ece802ae4e0a15375027284a78b