Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M Keith Howard"'
Autor:
Walter Wodal, Michael G Schwendinger, Helga Savidis-Dacho, Brian A Crowe, Christine Hohenadl, Richard Fritz, Peter Brühl, Daniel Portsmouth, Anita Karner-Pichl, Dalida Balta, Leopold Grillberger, Otfried Kistner, P Noel Barrett, M Keith Howard
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0113963 (2015)
BackgroundA novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus H7N9 vaccine in small animal models.Met
Externí odkaz:
https://doaj.org/article/2bb777705a7545578c212cdb0bec60d6
Autor:
M Keith Howard, Nicolas Sabarth, Helga Savidis-Dacho, Daniel Portsmouth, Otfried Kistner, Thomas R Kreil, Hartmut J Ehrlich, P Noel Barrett
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23791 (2011)
Vero cell culture-derived whole-virus H5N1 vaccines have been extensively tested in clinical trials and consistently demonstrated to be safe and immunogenic; however, clinical efficacy is difficult to evaluate in the absence of wide-spread human dise
Externí odkaz:
https://doaj.org/article/205eb7c48865410f8d91f4c9ce60e609
Autor:
Ellie Hayhurst, Emily Rose, Miriam Pedrera, Jane C. Edwards, Natalia Kotynska, Daisy Grainger, Yashar Sadigh, John Flannery, Ludo Bonnet, Ritwik Ritwik, Pawan Dulal, M. Keith Howard, Simon P. Graham
Publikováno v:
Vaccines; Volume 10; Issue 11; Pages: 1836
Solid dose vaccine formulation and delivery systems offer potential advantages over traditional liquid vaccine formulations. In addition to enhanced thermostability, needle-free delivery of unit solid dose injectable (USDI) vaccines offers safe, rapi
Autor:
Yvonne Beck, Alexandra Löw-Baselli, M. Keith Howard, Doris Kölch, Reinhard Ilk, Eva-Maria Pöllabauer, Stefan Kiermayr, Daniel Portsmouth, P. Noel Barrett, Richard Fritz, Klaus Orlinger, Thomas R. Kreil, Annett Hessel
Publikováno v:
Journal of Virology
Studies evaluating the immunogenicity of two pediatric tick-borne encephalitis virus (TBEV) vaccines have reported contradictory results. These vaccines are based on two different strains of the European TBEV subtype: FSME-Immun Junior is based on th
Autor:
Timo Vesikari, Otfried Kistner, Peter Richmond, Thomas Dvorak, Javier Díez-Domingo, Thomas R. Kreil, P. Noel Barrett, Eva Maria Pöllabauer, Bee Wah Lee, Hartmut J. Ehrlich, Sandor Fritsch, Richard Fritz, Maikel V. W. van der Velden, M. Keith Howard, Gerald Aichinger, Daniel Portsmouth
Publikováno v:
Journal of Infectious Diseases. 209:12-23
BACKGROUND: Children are highly vulnerable to infection with novel influenza viruses. It is essential to develop candidate pandemic influenza vaccines that are safe and effective in the pediatric population. METHODS: Infants and children aged 6-35 mo
Autor:
Brian A. Crowe, Nicolas Sabarth, Daniel Portsmouth, Helga Savidis-Dacho, Michael G. Schwendinger, P. Noel Barrett, M. Keith Howard, Thomas R. Kreil, Otfried Kistner, Peter Brühl
Publikováno v:
Vaccine. 30:5533-5540
Background Preparation for an H5N1 influenza pandemic in humans could include priming the population in the pre-pandemic period with a vaccine produced from an existing H5N1 vaccine strain, with the possibility of boosting with a pandemic virus vacci
Autor:
Astrid Kerschbaum, Claudia Gaiswinkler, Thomas R. Kreil, Walter Wodal, M. Keith Howard, Falko G. Falkner, Daniel Portsmouth, Helga Savidis-Dacho, Richard Fritz, Sogue Coulibaly, Otfried Kistner, Stefan Kiermayr, Christina Piskernik, P. Noel Barrett, Christine Hohenadl
Publikováno v:
Vaccine. 30:4625-4631
Background Influenza viruses of subtype A/H9N2 are enzootic in poultry across Asia and the Middle East and are considered to have pandemic potential. The development of new vaccine manufacturing technologies is a cornerstone of influenza pandemic pre
Autor:
Sandra M. Leydold, Gerhard Pölsler, Andreas Berting, Johanna Kindermann, P. Noel Barrett, Maria R. Farcet, M. Keith Howard, Thomas R. Kreil, Jens Modrof
Publikováno v:
Transfusion. 52:2122-2130
BACKGROUND: Chikungunya virus (CHIKV) outbreaks were previously restricted to parts of Africa, Indian Ocean Islands, South Asia, and Southeast Asia. In 2007, however, the first autochthonous CHIKV transmission was reported in Europe. High-level virem
Publikováno v:
Expert Review of Vaccines. 8:607-618
The development of cell culture systems for virus propagation has led to major advances in virus vaccine development. Primary and diploid cell culture systems are now being replaced by the use of continuous cell lines (CCLs). These substrates are gai
Autor:
Dalida Balta, Walter Wodal, Anita Karner-Pichl, Otfried Kistner, Brian A. Crowe, Peter Brühl, Helga Savidis-Dacho, Leopold Grillberger, M. Keith Howard, Richard Fritz, P. Noel Barrett, Michael G. Schwendinger, Daniel Portsmouth, Christine Hohenadl
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0113963 (2015)
PLoS ONE, Vol 10, Iss 2, p e0113963 (2015)
BackgroundA novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus H7N9 vaccine in small animal models.Met