Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array data.

Autor: Orna Mizrahi-Man, Marcos H Woehrmann, Teresa A Webster, Jeremy Gollub, Adrian Bivol, Sara M Keeble, Katherine H Aull, Anuradha Mittal, Alan H Roter, Brant A Wong, Jeanette P Schmidt

Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0277680 (2022)

The UK Biobank genotyped about 500k participants using Applied Biosystems Axiom microarrays. Participants were subsequently sequenced by the UK Biobank Exome Sequencing Consortium. Axiom genotyping was highly accurate in comparison to sequencing resu

Externí odkaz: https://doaj.org/article/78ad3478be78444e82f37b1b17281b24

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The genomic basis of environmental adaptation in house mice.

Autor: Megan Phifer-Rixey, Ke Bi, Kathleen G Ferris, Michael J Sheehan, Dana Lin, Katya L Mack, Sara M Keeble, Taichi A Suzuki, Jeffrey M Good, Michael W Nachman

Publikováno v: PLoS Genetics, Vol 14, Iss 9, p e1007672 (2018)

House mice (Mus musculus) arrived in the Americas only recently in association with European colonization (~400-600 generations), but have spread rapidly and show evidence of local adaptation. Here, we take advantage of this genetic model system to i

Externí odkaz: https://doaj.org/article/2c291b6a9449440c8109e9772ebbcd50

The Regional Aerosol Model Intercomparison Project (RAMIP)

Autor: Laura J. Wilcox, Robert J. Allen, Bjørn H. Samset, Massimo A. Bollasina, Paul T. Griffiths, James M. Keeble, Marianne T. Lund, Risto Makkonen, Joonas Merikanto, Declan O'Donnell, David J. Paynter, Geeta G. Persad, Steven T. Rumbold, Toshihiko Takemura, Kostas Tsigaridis, Sabine Undorf, Daniel M. Westervelt

Publikováno v: Wilcox, L J, Allen, R J, Samset, B H, Bollasina, M, Griffiths, P T, Keeble, J M, Lund, M T, Makkonen, R, Merikanto, J, O'Donnell, D, Paynter, D J, Persad, G G, Rumbold, S T, Takemura, T, Tsigaridis, K, Undorf, S & Westervelt, D 2022 ' The Regional Aerosol Model Intercomparison Project (RAMIP) ' . https://doi.org/10.5194/gmd-2022-249

Changes in anthropogenic aerosol emissions have strongly contributed to global and regional trends in temperature, precipitation, and other climate characteristics, and have been one of the dominant drivers of decadal trends in Asian and African prec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39186d921a3f6cf07189edc7bcbafe0c
https://doi.org/10.5194/gmd-2022-249

19 'Love The Day Job Still;' 'More Job Satisfaction;' 'I Will Never Give Up My GeriGP Job;' - Results of the BGS GeriGP Workforce Survey 2018

Autor: M Keeble, E Kalmus, K Davies, L Lawn

Publikováno v: Age and Ageing. 49:i1-i8

Background In 2017, two GPs decided to form the GeriGP group, for BGS GP members with a particular interest in the care of older people. GPs are increasingly using their holistic approach and expertise in new models of care within the community and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2785432d4fd454d58b183be54fb0023
https://doi.org/10.1093/ageing/afz183.19