Zobrazeno 1 - 10
of 65
pro vyhledávání: '"M Kathryn Iovine"'
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148202 (2016)
Skeletal development is a tightly regulated process and requires proper communication between the cells for efficient exchange of information. Analysis of fin length mutants has revealed that the gap junction protein Connexin43 (Cx43) coordinates cel
Externí odkaz:
https://doaj.org/article/5775c628329b4a0a908fa2ab1e88c08c
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116368 (2015)
Plexins (plxns) are transmembrane (TM) receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well as cancer metastasis. Plxn signaling results in cytosolic GTPase-activating protein activity, and previous research imp
Externí odkaz:
https://doaj.org/article/1f2ff6c3914b493889de2b6cc9825b7a
Hapln1a is required for connexin43-dependent growth and patterning in the regenerating fin skeleton.
Autor:
Jayalakshmi Govindan, M Kathryn Iovine
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88574 (2014)
Cell-cell communication, facilitating the exchange of small metabolites, ions and second messengers, takes place via aqueous proteinaceous channels called gap junctions. Connexins (cx) are the subunits of a gap junction channel. Mutations in zebrafis
Externí odkaz:
https://doaj.org/article/e30fbf25a573482b9f790ea655561e4e
Autor:
Quynh V Ton, M Kathryn Iovine
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81240 (2013)
Joints are essential for skeletal flexibly and form, yet the process underlying joint morphogenesis is poorly understood. Zebrafish caudal fins are comprised of numerous segmented bony fin rays, where growth occurs by the sequential addition of new s
Externí odkaz:
https://doaj.org/article/f12671105e1e441180475fed4cac03c6
Autor:
Sarah V Gerhart, Diane M Eble, R Michael Burger, Stefan N Oline, Ana Vacaru, Kirsten C Sadler, Rebecca Jefferis, M Kathryn Iovine
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31364 (2012)
Connexins (Cx) are the subunits of gap junctions, membraneous protein channels that permit the exchange of small molecules between adjacent cells. Cx43 is required for cell proliferation in the zebrafish caudal fin. Previously, we found that a Cx43-l
Externí odkaz:
https://doaj.org/article/0a672a21460040abae76a483729614a1
Publikováno v:
Biology Open, Vol 6, Iss 12, Pp 1802-1813 (2017)
Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial deformities, limb malformation and mental retardation. These birth defects are collectively termed cohesinopathies as both ari
Externí odkaz:
https://doaj.org/article/440f175471b14a8db8dd519da9ec6221
Autor:
Michael G. Mfarej, Caitlin A. Hyland, Annie C. Sanchez, Matthias M. Falk, M. Kathryn Iovine, Robert V. Skibbens
Publikováno v:
Molecular Biology of the Cell. 34
Cohesins are ATPase complexes that play central roles in cellular processes such as chromosome division, DNA repair, and gene expression. Cohesinopathies arise from mutations in cohesin proteins or cohesin complex regulators and encompass a family of
Publikováno v:
Cell Cycle. 21:501-513
Autor:
Cassandra J. Field, Alexis M. Perez, Taryn Samet, Victoria Ricles, M. Kathryn Iovine, Linda J. Lowe-Krentz
Publikováno v:
Frontiers in physiology. 13
Angiogenesis, the outgrowth of new blood vessels from existing vasculature, is critical during development, tissue formation, and wound healing. In response to vascular endothelial growth factors (VEGFs), endothelial cells are activated to proliferat
Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of cohesin (including SMC3, CdLS) and ESCO2 (RBS). Though ESCO2 activate cohesin, CdLS and RBS etiologies are currently considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020d25ccc093e20ae9c175b751348a73
https://doi.org/10.1101/2020.09.02.280149
https://doi.org/10.1101/2020.09.02.280149