Zobrazeno 1 - 10
of 45
pro vyhledávání: '"M K Liszewski"'
Autor:
Peter Kang, Slim Fellah, Michael M Binkley, Yasheng Chen, M. K Liszewski, Jin-Moo Lee, Jonathan Miner, John P Atkinson, Hongyu An, Andria L Ford
Publikováno v:
Stroke. 54
Background: A rare, monogenic cerebral small vessel disease (cSVD), retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S), is associated with progressive cerebral ischemia and accelerated vascular cognitive impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c9bc9670be84d5bec1faa58c071218c
https://doi.org/10.1161/str.54.suppl_1.129
https://doi.org/10.1161/str.54.suppl_1.129
Autor:
M K Liszewski, John P. Atkinson
Publikováno v:
Journal of internal medicine. 277(3)
First identified in human serum in the late 19th century as a ‘complement’ to antibodies in mediating bacterial lysis, the complement system emerged more than a billion years ago probably as the first humoral immune system. The contemporary compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168511cbf3c5f4e77e2557f5f994a89b
https://pubmed.ncbi.nlm.nih.gov/25495259
https://pubmed.ncbi.nlm.nih.gov/25495259
Autor:
M K Liszewski, John P. Atkinson
Publikováno v:
Expert Opinion on Investigational Drugs. 7:323-331
The complement system provides natural immunity against microbes and is an effector arm of antibody-mediated humoral immunity. It promotes the inflammatory process by activating cells and facilitates microbial destruction through opsonisation and lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e9f62cf34f92858fd6b1c8cf735ba5
https://doi.org/10.1517/13543784.7.3.323
https://doi.org/10.1517/13543784.7.3.323
Publikováno v:
Journal of Biological Chemistry. 272:20793-20799
Membrane cofactor protein (MCP) is a widely distributed complement regulatory protein that is expressed on the basolateral surface of polarized epithelial cells. The basolateral targeting of the BC1 isoform of MCP was analyzed by generating deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae7186f712b4cedeff9bdaccd007fb4
https://doi.org/10.1074/jbc.272.33.20793
https://doi.org/10.1074/jbc.272.33.20793
Autor:
M K Liszewski, J P Atkinson
Publikováno v:
The Journal of Immunology. 156:4415-4421
Membrane cofactor protein (MCP; CD46) is a widely distributed C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. MCP is expressed primarily as four isoforms that arise by alternative splicing of a single gene. The differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13a45b92381a96f05cf8a248cbd11050
https://doi.org/10.4049/jimmunol.156.11.4415
https://doi.org/10.4049/jimmunol.156.11.4415
Autor:
Alexandra Valsamakis, Michael B. A. Oldstone, John P. Atkinson, J. Alvarez, M K Liszewski, Douglas M. Lublin, Marianne Manchester, Richard M. Kaufman
Publikováno v:
Proceedings of the National Academy of Sciences. 92:2303-2307
The human complement regulatory protein membrane cofactor protein (CD46) is the cellular receptor for measles virus (MV), whereas decay accelerating factor (DAF; CD55), a structurally similar complement regulatory protein, does not bind MV. To charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272945fc012fe08b9cab0ace3774e633
https://doi.org/10.1073/pnas.92.6.2303
https://doi.org/10.1073/pnas.92.6.2303
Publikováno v:
Scopus-Elsevier
The complement system, especially the early components of the classic pathway, are critically involved in immune complex processing. The deposition of clusters of complement component C3b on a target marks it for elimination, primarily through an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eea13045c9a4486bcb0411c967c6cb1
https://doi.org/10.1016/s0889-857x(21)00156-3
https://doi.org/10.1016/s0889-857x(21)00156-3
Publikováno v:
The Journal of Experimental Medicine
The cleavage of C3 is a critical step for complement (C) activation in the classical and alternative pathways. This reaction is controlled by the regulators of C activation protein family. Membrane cofactor protein (MCP) is a cofactor for the factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b25774d2fe90b62541b69d7ee23ba43
https://doi.org/10.1084/jem.175.6.1547
https://doi.org/10.1084/jem.175.6.1547
Publikováno v:
Clinical and Experimental Immunology. 86:27-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27113e15e9879fef67e925baa79c0b0a
https://doi.org/10.1111/j.1365-2249.1991.tb06203.x
https://doi.org/10.1111/j.1365-2249.1991.tb06203.x
Publikováno v:
The Journal of Experimental Medicine
Membrane cofactor protein (MCP) is a complement regulatory protein that is expressed on human cells and cell lines as two relatively broad species with Mr of 58,000-68,000 and 48,000-56,000. The structure of a previously reported cDNA clone indicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe60508ea66348652a96d94d7e201c6
http://europepmc.org/articles/PMC2118878
http://europepmc.org/articles/PMC2118878