Výsledky vyhledávání - "M K Holloway"

An Implementation of a Computerized Cognitive Behavioral Treatment Program to Address Student Mental Health Needs: A Pilot Study in an After-School Program

Autor: Sara Sanders, Samantha M. K. Holloway, Mickey Losinski, Abdullah Asiri, Jessica Nelson, Jessica J. Lane, Elizabeth Rogers

Publikováno v: Professional School Counseling. 22:2156759X1983846

This study evaluated the feasibility and effectiveness of an abbreviated computerized cognitive behavioral therapy (CCBT) software program, Camp Cope-A-Lot, in an after-school setting for elementary students identified as at risk for anxiety and othe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9d0cf023928d689021f336a828191e7
https://doi.org/10.1177/2156759x19838462

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Akademický článek

Rapid Synthesis of anti-1,3-Diamino-4-phenylbutan-2-ol Building Blocks via a Three-Component Oxyhomologation and a Two-Component Reducing System.

Autor: Cabua MC; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France.; Department of Chemical and Geological Science, University of Cagliari, S.P. No. 8 Km 0.700, 09042, Monserrato, Italy., He X; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France., Secci F; Department of Chemical and Geological Science, University of Cagliari, S.P. No. 8 Km 0.700, 09042, Monserrato, Italy., Deloisy S; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France., Aitken DJ; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France.

Publikováno v: ChemistryOpen [ChemistryOpen] 2024 Oct 30, pp. e202400279. Date of Electronic Publication: 2024 Oct 30.

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A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site

Autor: M K, Holloway, J M, Wai, T A, Halgren, P M, Fitzgerald, J P, Vacca, B D, Dorsey, R B, Levin, W J, Thompson, L J, Chen, S J, deSolms

Publikováno v: Journal of Medicinal Chemistry. 38:305-317

We have observed a high correlation between the intermolecular interaction energy (E inter ) calculated for HIV-1 protease inhibitor complexes and the observed in vitro enzyme inhibition. A training set of 33 inhibitors containing modifications in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7828284b4e63a048f50ded515d7ac8fd
https://doi.org/10.1021/jm00002a012

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Conformationally constrained HIV-1 protease inhibitors

Autor: P.M.D. Fitzgerald, Joel R. Huff, Ken E. Starbuck, L.J. Chen, Hungate Randall W, Paul L. Darke, P. S. Anderson, M. K. Holloway, J. P. Vacca

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 4:499-504

The synsthesis and structure activity relationships of conformationally constrained analogs of the HIV-1 protease inhibitor L-685,434 are described. In addition, the X-ray crystal structure of a complex between L-700,497 and the HIV-1 protease is sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de8a47cac47dcdde2e49870c8cae019d
https://doi.org/10.1016/0960-894x(94)80025-1

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