Zobrazeno 1 - 10
of 64
pro vyhledávání: '"M K Hoffmann"'
Autor:
G, Arentz, P, Mittal, C, Zhang, Y-Y, Ho, M, Briggs, L, Winderbaum, M K, Hoffmann, P, Hoffmann
Publikováno v:
Advances in cancer research. 134
Pathologists play an essential role in the diagnosis and prognosis of benign and cancerous tumors. Clinicians provide tissue samples, for example, from a biopsy, which are then processed and thin sections are placed onto glass slides, followed by sta
Publikováno v:
The Journal of Immunology. 149:3463-3467
Accessory cells present Ag together with costimulatory signals as immunogens and without costimulatory signals as tolerogens. Responsiveness and unresponsiveness are thus alternatives of T cell immune reactions to Ag. Superantigens appear to make an
Publikováno v:
The Journal of Immunology. 147:2833-2838
We examined the accessibility of the thymus to a self-super-Ag encoded by the Mls-1a region of chromosome 1 and the process by which this Ag establishes immunologic tolerance. Intravenously administered Mls-1a Ag accumulates quickly in peripheral org
Publikováno v:
The Journal of Immunology. 146:2083-2087
T cells expressing V beta 6 variable gene segments of the T cell receptor undergo blast formation and divide in mice after injection of lymphoid cells bearing minor lymphocyte-stimulating (Mls)-1a gene products. This in vivo Mls-1a response resembles
Publikováno v:
The Journal of Immunology. 144:1361-1368
Aggregation (e.g., through cross-linkage) of cell surface molecules is in various biologic systems a necessary event in cellular activation. Examining the Ia molecule on B cells we found that aggregation is a function of the surface Ag mobility; the
Publikováno v:
The Journal of Immunology. 144:1369-1374
Ia-reactive immunogenic peptides have been shown to immobilize Ia molecules on the B cell surface and to facilitate their aggregation with specific alloantibody. We show that to immobilize Ia the peptide must be amphipathic. Polar peptides appear to
Publikováno v:
Immunology. 102(3)
The development of monocytes into macrophages is regulated by helper T cells (Th) cells and, vice versa, the differentiation of Th cells into Th1 and Th2 is regulated by macrophages. Herein we examined the role of the Th2 cytokine, interleukin-10 (IL
Publikováno v:
Immunology. 87(1)
The primary and secondary immune response of V beta 8+ T cells to the bacterial superantigen Staphylococcus enterotoxin B was compared in BALB/c mice. Secondary responder T cells were found to up-regulate the expression of the adhesion molecule LFA-1
Publikováno v:
Immunodeficiency. 4(1-4)
In vivo administration of superantigens leads to activation and subsequent depletion or anergy of T cells expressing defined V beta-T cell receptors (TCR). Superantigens have therefore become intensively studied tools for examining parameters of immu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 149(11)
Accessory cells present Ag together with costimulatory signals as immunogens and without costimulatory signals as tolerogens. Responsiveness and unresponsiveness are thus alternatives of T cell immune reactions to Ag. Superantigens appear to make an