Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M K, McMillian"'
Autor:
M K, McMillian, L, Li, J B, Parker, L, Patel, Z, Zhong, J W, Gunnett, W J, Powers, M D, Johnson
Publikováno v:
Cell biology and toxicology. 18(3)
A simple resazurin-based cytotoxicity assay is presented for screening of cytotoxicity in hepatocytes and liver cell lines. Human hepatoma (HepG2) cells in 96-well culture plates were exposed to known toxic (cisplatin, 5-fluorouracil, ethionine, fluf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d915cbbbd87340b4074e124b41b545f
https://pubmed.ncbi.nlm.nih.gov/12083422
https://pubmed.ncbi.nlm.nih.gov/12083422
Publikováno v:
Journal of leukocyte biology. 70(4)
Apolipoprotein E (ApoE) is a 34-kDa cholesterol transport protein that also possesses immunomodulatory properties. In this study, we demonstrate that ApoE initiates a signaling cascade in murine peritoneal macrophages that leads to increased producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ac752a393e6f465437cf50cb052c1cf
https://pubmed.ncbi.nlm.nih.gov/11590206
https://pubmed.ncbi.nlm.nih.gov/11590206
Autor:
E R, Grant, M A, Errico, S L, Emanuel, D, Benjamin, M K, McMillian, S A, Wadsworth, R A, Zivin, Z, Zhong
Publikováno v:
Biochemical pharmacology. 62(3)
Excessive levels of the neurotransmitter glutamate trigger excitotoxic processes in neurons that lead to cell death. N-Methyl-D-aspartate (NMDA) receptor over-activation is a key excitotoxic stimulus that leads to increases in intracellular calcium a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::347ec9deb4610e812ab8d118d1e1a739
https://pubmed.ncbi.nlm.nih.gov/11434901
https://pubmed.ncbi.nlm.nih.gov/11434901
Publikováno v:
Brain research. 729(1)
Nitric oxide (NO) produced by glial cells has been implicated in the neuropathogenesis of various diseases. However, the signaling transduction pathway(s) for the production of NO in these cells is not well understood. To test whether protein tyrosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48159bd74cbd847213cd7fa422f2eeea
https://pubmed.ncbi.nlm.nih.gov/8874881
https://pubmed.ncbi.nlm.nih.gov/8874881
Publikováno v:
Glia. 16(4)
Administration of kainate (KA), a glutamate receptor agonist, to rats causes neuronal damage in the CA1/CA3 fields of the hippocampus and in the pyriform/ entorhinal cortex. Reactive gliosis also occurs and activated astrocytes upregulate their expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8d2771c51b032a09198b54df4a97ec1
https://pubmed.ncbi.nlm.nih.gov/8721671
https://pubmed.ncbi.nlm.nih.gov/8721671
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 8(8)
The AP-1 transcription factor family consists of two groups of proteins, fos-related antigens (fra) and jun proteins. These transcription factors are usually expressed at low basal levels but they can be dramatically induced in a variety of cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e62fc583a139117ebce71daf7fb62d2
https://pubmed.ncbi.nlm.nih.gov/8181665
https://pubmed.ncbi.nlm.nih.gov/8181665
Autor:
M K, McMillian, J S, Hong
Publikováno v:
Critical reviews in neurobiology. 9(1)
Cultured glial cells synthesize a number of neuropeptides, growth factors, cytokines, and other factors that are not detectable in resting glia in the adult brain but that appear in response to brain injury. Enkephalin-containing peptides are produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91506699715776b33d57cfa372dcba7b
https://pubmed.ncbi.nlm.nih.gov/8828005
https://pubmed.ncbi.nlm.nih.gov/8828005
Publikováno v:
The Biochemical journal. 255(1)
The effects of extracellular ATP on intracellular free calcium concentration [( Ca2+]i), phosphatidylinositol (PtdIns) turnover, amylase release and Ca2+-activated membrane currents were examined in isolated rat parotid acinar cells and contrasted wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69459f33834baee7c78ce8c5382b88f8
https://pubmed.ncbi.nlm.nih.gov/2848507
https://pubmed.ncbi.nlm.nih.gov/2848507
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 225(1)
We have previously reported that maternal deprivation of rat pups causes a decrease in tissue responsiveness to growth hormone that is mediated by the loss of maternal tactile stimulation. We now report that liver responses to alpha and beta adrenerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e934df5e5b138999d5f08a9fed46c69d
https://pubmed.ncbi.nlm.nih.gov/6132000
https://pubmed.ncbi.nlm.nih.gov/6132000
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 235(2)
Short-term food deprivation (FD) of preweanling rat pups causes a marked and specific suppression of liver ornithine decarboxylase (ODC) induction by alpha and beta adrenergic agonists that is mediated by postreceptor mechanisms. In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a434132711444cd3e264ea975e3e4318
https://pubmed.ncbi.nlm.nih.gov/2865350
https://pubmed.ncbi.nlm.nih.gov/2865350