Zobrazeno 1 - 10 of 21 pro vyhledávání: '"M K, Howett"'
1
Enhancement of morphological and oncogenic transformation of mouse cells with 12-0-tetra-decanoyl phorbol-13-acetate following herpes sinplex virus type 2 infection
Autor: Chen Minhui, Lin Yulin, M K Howett, Chen Xiao, F Rapp, Chen Daoping, Z Korsunsky
Publikováno v: Chinese Journal of Cancer Research. 6:191-199
Sequential exposure of mouse embryo cells to HSV-2 and TPA gave rise to a synergistic enhancement of the transformation frequency. The transformants were selected for their ability to form dense foci of cells in medium containing 10% or 1% (low) feta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d64aea60e258c333e86970eef205b2aa
https://doi.org/10.1007/bf02672272
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2
Human Xenografts
Autor: J W Kreider, K D Cockley, M K Howett
Publikováno v: Intervirology. 31:109-115
Epithelial chips of human foreskin or cervix infected in vitro with one strain of human papillomavirus type 11 (HPV-11) and subsequently transplanted to the renal capsule of athymic mice will yield, after 3 months of in vivo incubation, epithelial cy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72d87009c29e7d90ffe09be3ba79345d
https://doi.org/10.1159/000150144
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4
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta
Autor: Mitchell F. Denning, Andrzej A. Dlugosz, Stuart H. Yuspa, M K Howett
Publikováno v: Journal of Biological Chemistry. 268:26079-26081
Murine keratinocytes expressing an oncogenic rasHa gene produce benign tumors in vivo and demonstrate altered responses to phorbol esters in vitro. Cultured keratinocytes transduced with the v-rasHa gene (v-rasHa keratinocytes) are resistant to Ca(2+
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9606dc7c693f2ccce87a6eb1ba738348
https://doi.org/10.1016/s0021-9258(19)74282-3
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5
Immunological characterization of human vaginal xenografts in immunocompromised mice: development of a small animal model for the study of human immunodeficiency virus-1 infection
Autor: T M, Kish, L R, Budgeon, P A, Welsh, M K, Howett
Publikováno v: The American journal of pathology. 159(6)
A small animal model for the in vivo study of human immunodeficiency virus-1 and other fastidious infectious agents in human host target tissues is critical for the advancement of therapeutic and preventative strategies. Our laboratory has developed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0012f8cfb80db9f37701b07b4a9424b8
https://pubmed.ncbi.nlm.nih.gov/11733382
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6
Correlation of TGF beta 1 overexpression with down-regulation of proliferation-inducing molecules in HPV-11 transformed human tissue xenografts
Autor: M K, Shier, E B, Neely, M G, Ward, M E, Richards, E C, Manders, C, Meyers, M K, Howett
Publikováno v: Anticancer research. 19(6B)
The epidemiologic association of human papillomavirus (HPV) infection with dysplasia and cervical cancer is well established. Transforming growth factor beta 1 (TGF beta 1) has regulatory effects on a broad spectrum of cell types and is a growth inhi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55591a0b48b607b3b1fdbf2d383a0433
https://pubmed.ncbi.nlm.nih.gov/10697498
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7
Transforming growth factor beta 1 (TGF beta 1) down-regulates expression and function of proliferation-inducing molecules in HPV-transformed cells
Autor: M K, Shier, E B, Neely, M G, Ward, C, Meyers, M K, Howett
Publikováno v: Anticancer research. 19(6B)
The epidemiologic association of human papillomavirus (HPV) infection with dysplasia and cervical cancer is well established. Transforming growth factor beta 1 (TGF beta 1) is a growth inhibitory protein for epithelial cells. To examine the phenotype
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d76fa609dc31c2f44bfa5316fea4ee8
https://pubmed.ncbi.nlm.nih.gov/10697499
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9
Localization of protein kinase C alpha isoform expression in the human gastrointestinal tract
Autor: T J, McGarrity, L P, Peiffer, E B, Neely, R G, Palavarapu, W A, Koltun, P, Parker, M K, Howett
Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(7)
Protein kinase C (PKC) includes a family of related proteins which constitutes a major signal transduction pathway. The aim of this study was to determine the localization of the PKC-alpha isoform throughout the human gastrointestinal tract. PKC-alph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f1cd10736030dec862baf5f3099924c9
https://pubmed.ncbi.nlm.nih.gov/8809413
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10
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta
Autor: M F, Denning, A A, Dlugosz, M K, Howett, S H, Yuspa
Publikováno v: The Journal of biological chemistry. 268(35)
Murine keratinocytes expressing an oncogenic rasHa gene produce benign tumors in vivo and demonstrate altered responses to phorbol esters in vitro. Cultured keratinocytes transduced with the v-rasHa gene (v-rasHa keratinocytes) are resistant to Ca(2+
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e2009b1a870a1d53fe0d4f0cc365aa9
https://pubmed.ncbi.nlm.nih.gov/8253722
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