Zobrazeno 1 - 6
of 6
pro vyhledávání: '"M K, Grizzle"'
Autor:
M, Dezube, E E, Sugg, L S, Birkemo, D K, Croom, R W, Dougherty, G N, Ervin, M K, Grizzle, M K, James, M F, Johnson, J T, Mosher
Publikováno v:
Journal of Medicinal Chemistry. 38:3384-3390
Hybrid analogs of the cholecystokinin A (CCK-A) receptor selective tetrapeptide agonist Boc-Trp-Lys(Tac)-Asp-MePhe-NH2 (1,A-71623) and the CCK-B receptor selective antagonists PD-135118 (2) and CI-988 (3) were prepared. Incorporation of the Lys(Tac)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27fef768e02c3704c4c326c8e7ff5b1
https://doi.org/10.1021/jm00017a022
https://doi.org/10.1021/jm00017a022
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 265(3)
The hemodynamic and beta adrenergic blocking effects of GI104313, a chimeric molecule containing a phosphodiesterase-inhibiting pyradazinone and a beta blocking phenoxpropanolamine, were examined in barbiturate-anesthetized, vagotomized dogs. The res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb73f7a5c08ad4f9b78bb95dfe4972f6
https://pubmed.ncbi.nlm.nih.gov/8099617
https://pubmed.ncbi.nlm.nih.gov/8099617
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(1)
Hemodynamic effects of GI 87084B, a novel ultra-short acting mu-opioid agonist, were studied in anesthetized dogs. In these studies, GI 87084B (0.3-20 nmol/kg/min i.v.) produced dose-dependent decreases in heart rate, arterial blood pressure, +dP/dt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::050fd1f06d49f5e6f5e908fd5ee41e02
https://pubmed.ncbi.nlm.nih.gov/1403806
https://pubmed.ncbi.nlm.nih.gov/1403806
Publikováno v:
Journal of Applied Physiology. 63:2426-2432
We hypothesized that toxic O2 radicals might be important mediators of endotoxin-induced acute respiratory failure in pigs. As a relatively specific scavenger of .OH, we infused dimethylthiourea (DMTU, 1 g/kg) before endotoxemia. Escherichia coli end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83553baaf6443da3797942a36c9ade69
https://doi.org/10.1152/jappl.1987.63.6.2426
https://doi.org/10.1152/jappl.1987.63.6.2426
Publikováno v:
Journal of Applied Physiology. 63:1526-1532
We hypothesized that superoxide anion (O2-.) and hydrogen peroxide (H2O2) might be important mediators of endotoxin-induced acute respiratory failure (ARF) in pigs. As specific scavengers of O2-. and H2O2, we infused polyethylene glycol-superoxide di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcb0b881895b603c654dae63c753a14
https://doi.org/10.1152/jappl.1987.63.4.1526
https://doi.org/10.1152/jappl.1987.63.4.1526
Publikováno v:
American journal of veterinary research. 47(10)
The effects of ketanserin on pulmonary hemodynamics, lung mechanics, and gas exchange were determined in anesthetized 10- to 14-week-old pigs after they were endotoxemic for 1 or 4.5 hours. Saline solution was given to controls (group 1). Escherichia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c073286c7b703288a2f805a5937dc7c
https://pubmed.ncbi.nlm.nih.gov/3777645
https://pubmed.ncbi.nlm.nih.gov/3777645