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Autor:
M, Barrois, M K, Eychenne, M J, Terrier-Lacombe, N, Duarte, C, Dubourg, S, Douc-Rasy, A, Chompret, M, Khagad, O, Hartmann, D, Caput, J, Bénard
Publikováno v:
Medical and pediatric oncology. 36(1)
The p53 gene homologue, p73, is located on the 1p36-3 locus, which is frequently deleted in human neuroblastoma (NB). A survey of 61 NB showed that among 33% of informative cases, p73 loss of heterozygosity (LOH) occurred in 7 of 20 (35%).LOH pattern