Zobrazeno 1 - 10
of 81
pro vyhledávání: '"M Jurima-Romet"'
Publikováno v:
Toxicology in Vitro. 14:253-263
The pig is increasingly being used in pharmacological and toxicological studies, and is the species of choice for future research into xenotransplantation, extracorporeal liver support and hepatocyte-based bioartificial liver. However, relatively lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323277c13541406697cc71b22e1cdc42
https://doi.org/10.1016/s0887-2333(00)00016-3
https://doi.org/10.1016/s0887-2333(00)00016-3
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:165-172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14df0b5534fb298bb3d2d4d624d96c80
https://doi.org/10.1139/y97-013
https://doi.org/10.1139/y97-013
Publikováno v:
Toxicology in Vitro. 8:55-66
The cytotoxicities of 12 non-steroidal anti-inflammatory drugs (NSAIDs) in primary monolayer cultures of rat hepatocytes were compared. Toxicity was determined by measuring the release of lactate dehydrogenase into the culture medium after 20 hr of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386dea9cc0c482f10445ffe7c460281d
https://doi.org/10.1016/0887-2333(94)90208-9
https://doi.org/10.1016/0887-2333(94)90208-9
Publikováno v:
International Journal of Pharmaceutics. 88:201-210
Interest in the potential applications of liposomes for pulmonary drug delivery prompted this in vitro study of the effect of lipid composition on vesicle permeability. Rat cell-free bronchoalveolar lavage fluid was incubated at 37°C with large unil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076fee64e52858a1fead6c0d37510000
https://doi.org/10.1016/0378-5173(92)90317-u
https://doi.org/10.1016/0378-5173(92)90317-u
Autor:
M Jurima-Romet, P N Shek
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:6-10
The intratracheal delivery of glutathione (GSH), in liposome-encapsulated form, prolongs retention of the drug in the rat lung. This study has been designed to determine the extent and zime-course of pulmonary tissue uptake of administered 14C-labell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d54af0a51695a4a31cefc65e26a805d
https://doi.org/10.1111/j.2042-7158.1991.tb05438.x
https://doi.org/10.1111/j.2042-7158.1991.tb05438.x
Publikováno v:
FEMS Microbiology Letters. 72:249-252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082375bc81d064a04fbd29a444386f5e
https://doi.org/10.1111/j.1574-6968.1990.tb03897.x
https://doi.org/10.1111/j.1574-6968.1990.tb03897.x
Autor:
M. Jurima-Romet, H.S. Huang
Publikováno v:
Toxicology in Vitro. 8:529-531
Hepatotoxicity has been reported with angiotensin-converting enzyme (ACE) inhibitors. The mechanism of liver injury is not known. In the present study, primary rat hepatocytes were used to investigate the cytotoxicity of ACE inhibitors. Captopril, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341eec155867f7ba8ed1918bb3082fff
https://doi.org/10.1016/0887-2333(94)90007-8
https://doi.org/10.1016/0887-2333(94)90007-8
Publikováno v:
Canadian journal of physiology and pharmacology. 79(10)
CYP2C9 is the major P450 2C enzyme in human liver and contributes to the metabolism of a number of clinically important substrate drugs. This polymorphically expressed enzyme has been studied in Caucasian, Asian, and to some extent in African America
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4562975640d346ae2d5387b5c9510af
https://pubmed.ncbi.nlm.nih.gov/11697742
https://pubmed.ncbi.nlm.nih.gov/11697742
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(4)
A number of xenobiotics are known to exert their porphyrinogenic effects in rodents and chick embryos through mechanism-based inactivation of certain cytochrome P450 (P450) isozymes. To facilitate the extrapolation of results from test animals to hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f042a4f083ba929b43eea299b3ed24f9
https://pubmed.ncbi.nlm.nih.gov/9107543
https://pubmed.ncbi.nlm.nih.gov/9107543
Autor:
A P, Li, M, Jurima-Romet
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b84e05e1c8dbf2793d43ef55b10d3cdf
https://pubmed.ncbi.nlm.nih.gov/9342170
https://pubmed.ncbi.nlm.nih.gov/9342170