Zobrazeno 1 - 10
of 291
pro vyhledávání: '"M Johannes"'
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 6, Pp 3162-3169 (2024)
Abstract Background Information regarding response rate to tigilanol tiglate for mast cell tumors in dogs is limited. Objectives Report the response rate and durability of tigilanol tiglate intratumoral treatment in dogs with mast cell tumors present
Externí odkaz:
https://doaj.org/article/41a3474d48f841478cefbe13b6b24675
Autor:
Haylie C. Lawson, Margaret L. Musser, Rebecca Regan, Antony S. Moore, Ann Hohenhaus, Brian Flesner, Chad M. Johannes
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 1, Pp 234-243 (2022)
Abstract Background Despite multiple reports of chemotherapy overdoses (ODs) in human and veterinary medicine, anthracycline ODs have been described infrequently. Hypothesis/Objectives Describe toxicities, treatments, and overall outcome after anthra
Externí odkaz:
https://doaj.org/article/8b76ae9edcf14761854fcfd3b1510512
Akademický článek
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Akademický článek
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Autor:
Margaret L. Musser, Chad M. Johannes
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-6 (2021)
Abstract Background Canine pancreatic carcinoma is a rare, aggressive tumour that is often diagnosed late in the course of disease. Effective treatment strategies have been elusive, and overall survival time is short. In humans, treatment with tyrosi
Externí odkaz:
https://doaj.org/article/3303802635e54582aeffd92172561d08
Autor:
Thomas R. De Ridder, Justine E. Campbell, Cheryl Burke‐Schwarz, David Clegg, Emily L. Elliot, Samuel Geller, Wendy Kozak, Stephen T. Pittenger, Jennifer B. Pruitt, Jocelyn Riehl, Julie White, Melissa L. Wiest, Chad M. Johannes, John Morton, Pamela D. Jones, Peter F. Schmidt, Victoria Gordon, Paul Reddell
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 415-429 (2021)
Abstract Objective To evaluate the efficacy and safety of tigilanol tiglate (TT) for local intratumoral treatment of mast cell tumors (MCTs) in dogs. Methods A randomized controlled clinical study in 2 phases involving 123 dogs with cytologically dia
Externí odkaz:
https://doaj.org/article/1df0a2eb05904e1abae36124d5866f9c
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 451-455 (2021)
Abstract Background Tigilanol tiglate (TT) is a novel small molecule approved by the European Medicines Agency for intratumoral treatment of mast cell tumors (MCTs) in dogs. In a randomized controlled clinical efficacy and safety study in the United
Externí odkaz:
https://doaj.org/article/30866ecda9b14defb6f8f3736644451e
Autor:
Paul Reddell, Thomas R. De Ridder, John M. Morton, Pamela D. Jones, Justine E. Campbell, Graham Brown, Chad M. Johannes, Peter F. Schmidt, Victoria Gordon
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 430-441 (2021)
Abstract Background Tigilanol tiglate (TT) is a novel small molecule for intratumoral treatment of nonmetastatic mast cell tumors (MCTs) in dogs. In a randomized controlled clinical study, 75% of dogs that received a single TT treatment achieved comp
Externí odkaz:
https://doaj.org/article/ce30c3d533e44be39a8c2c5a3b666f9e
Autor:
Margaret L. Musser, Austin K. Viall, Rachel L. Phillips, Jesse M. Hostetter, Chad M. Johannes
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-10 (2020)
Abstract Background Chronic inflammation mediated by the cyclooxygenase enzymes, specifically their product prostaglandin E2 (PGE2), can result in the development of cancer. PGE2 promotes cell proliferation, apoptosis, and angiogenesis through intera
Externí odkaz:
https://doaj.org/article/e171a6fad89d4f7fb6289a9adf1dd8f8
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279594 (2022)
Canine splenic hemangiosarcoma (HSA) is an aggressive tumor with a short overall survival time (OST) despite treatment with splenectomy and adjuvant doxorubicin. Modulation of the immune system has been shown to be effective for a variety of human tu
Externí odkaz:
https://doaj.org/article/b298880c86734102b2054718e869cb43