Zobrazeno 1 - 10
of 35
pro vyhledávání: '"M Jill Saffrey"'
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166229 (2016)
Changes in appetite occur during the ovarian cycle in female mammals. Research on appetite-regulatory gastrointestinal peptides in females is limited, because reproductive changes in steroid hormones present additional experimental factors to control
Externí odkaz:
https://doaj.org/article/c692e08c10a24165a27b850dd355bc0f
Publikováno v:
Journal of Cellular and Molecular Medicine
Ageing is associated with impaired neuromuscular function of the terminal gastrointestinal (GI) tract, which can result in chronic constipation, faecal impaction and incontinence. Interstitial cells of cajal (ICC) play an important role in regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18104f3eb18afae3539a09cea125ba3d
https://doi.org/10.1111/jcmm.13794
https://doi.org/10.1111/jcmm.13794
Autor:
Taher Darreh-Shori, Mohamed A. Thaha, Joanne Chin-Aleong, Alexandra Palmer, M. Jill Saffrey, Joanne E. Martin, John Broad, Shezan Elahi, Shafi Ahmed, Victor W S Kung, Charles H. Knowles, Gareth J. Sanger, Azadeh Karami, Rebecca Carroll
Publikováno v:
Gut
ObjectiveTo determine if human colonic neuromuscular functions decline with increasing age.DesignLooking for non-specific changes in neuromuscular function, a standard burst of electrical field stimulation (EFS) was used to evoke neuronally mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5119efb950b54f1020a36ded87bcc30
Autor:
Annabelle Panossian, Leena Parmar, Bhavik Anil Patel, Chunfang Wang, Kasonde Mandona, Richard N. Ranson, Sara Fidalgo, Melanie S. Flint, Mark Yeoman, M. Jill Saffrey
Publikováno v:
Scientific Reports
Treatment for chronic constipation in older people is challenging and the condition has a major impact on quality of life. A lack of understanding about the causes of this condition has hampered the development of effective treatments. 5-HT is an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ce22933ea8c7a96aab8fd2d1e7acae
https://nrl.northumbria.ac.uk/id/eprint/29840/1/srep42754.pdf
https://nrl.northumbria.ac.uk/id/eprint/29840/1/srep42754.pdf
Autor:
Chunfang Wang, Mark Yeoman, Bhavik Anil Patel, Richard N. Ranson, Sara Fidalgo, Nikkita Patel, M. Jill Saffrey
Publikováno v:
Experimental Gerontology. 53:24-30
Aging is associated with an increased incidence of constipation in humans. The contribution that the aging process makes to this condition is unclear. The aim of this study was to determine the effects of age on fecal output and colonic motility in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9899443d3868d0ad94e2116857f1635
https://doi.org/10.1016/j.exger.2014.02.007
https://doi.org/10.1016/j.exger.2014.02.007
Autor:
Paul R. Heath, Julie E. Simpson, David Baker, Ignacio A. Romero, David Drew, Johnathan Cooper-Knock, Stephen B. Wharton, Chunfang Wang, Vicki Leach, Emily F. Goodall, M. Jill Saffrey
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3097 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences
Volume 20
Issue 12
Functional and structural age-associated changes in the blood-brain barrier (BBB) may affect the neurovascular unit and contribute to the onset and progression of age-associated neurodegenerative pathologies, including Alzheimer&rsquo
s disease.
s disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5765ecaca5bd8365b7d3095869d758
https://doi.org/10.3390/ijms20123097
https://doi.org/10.3390/ijms20123097
Publikováno v:
Reproduction Abstracts.
Introduction: Previous studies have established that litter size during lactation influences body size and adiposity in male rat pups, but female pups and appetite-regulatory hormones have not been studied in this way. Gastrointestinal hormones ghrel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21399c29a5773569a4a07df34099ed69
https://doi.org/10.1530/repabs.3.p043
https://doi.org/10.1530/repabs.3.p043
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166229 (2016)
PLoS ONE
PLOS ONE
PLoS ONE
PLOS ONE
Changes in appetite occur during the ovarian cycle in female mammals. Research on appetite-regulatory gastrointestinal peptides in females is limited, because reproductive changes in steroid hormones present additional experimental factors to control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425799b703d4b5789936adc66fffc479
http://europepmc.org/articles/PMC5102396?pdf=render
http://europepmc.org/articles/PMC5102396?pdf=render
Publikováno v:
Neuroscience Letters. 517:102-106
Oxidative stress is widely recognized to contribute to neuronal death during various pathological conditions and aging. In the enteric nervous system (ENS), reactive oxygen species have been implicated in the mechanism of age-associated neuronal loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d39d1be25cf2966d9251b04a8552dc
https://doi.org/10.1016/j.neulet.2012.04.036
https://doi.org/10.1016/j.neulet.2012.04.036
Autor:
M. Jill Saffrey
Publikováno v:
Mechanisms of Ageing and Development. 125:899-906
The intrinsic neurones of the enteric nervous system (ENS) play a fundamental role in the regulation of gastrointestinal functions. Although much remains to be learnt about the changes that take place in intestinal nerves during ageing, evidence sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a42c86bca3d2190e3c77cbbd4a266b
https://doi.org/10.1016/j.mad.2004.09.003
https://doi.org/10.1016/j.mad.2004.09.003