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Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin:A Metgen Meta-Analysis

Autor: T, Dujic, K, Zhou, S W, Yee, N, van Leeuwen, C E, de Keyser, M, Javorský, S, Goswami, L, Zaharenko, M M, Hougaard Christensen, M, Out, R, Tavendale, M, Kubo, M M, Hedderson, A A, van der Heijden, L, Klimčáková, V, Pirags, A, Kooy, K, Brøsen, J, Klovins, S, Semiz, I, Tkáč, B H, Stricker, Cna, Palmer, L M, 't Hart, K M, Giacomini, E R, Pearson

Publikováno v: Dujic, T, Zhou, K, Yee, S W, van Leeuwen, N, de Keyser, C E, Javorský, M, Goswami, S, Zaharenko, L, Hougaard Christensen, M M, Out, M, Tavendale, R, Kubo, M, Hedderson, M M, van der Heijden, A A, Klimčáková, L, Pirags, V, Kooy, A, Brøsen, K, Klovins, J, Semiz, S, Tkáč, I, Stricker, B H, Palmer, C N A, 't Hart, L M, Giacomini, K M & Pearson, E R 2017, ' Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin : A Metgen Meta-Analysis ', Clinical Pharmacology and Therapeutics, vol. 101, no. 6, pp. 763-772 . https://doi.org/10.1002/cpt.567
Clinical Pharmacology and Therapeutics, 101(6), 763-772
Dujic, T, Zhou, K, Yee, S W, van Leeuwen, N, de Keyser, C E, Javorský, M, Goswami, S, Zaharenko, L, Christensen, M M H, Out, M, Tavendale, R, Kubo, M, Hedderson, M M, van der Heijden, A A, Klimčáková, L, Pirags, V, Kooy, A, Brøsen, K, Klovins, J, Semiz, S, Tkáč, I, Stricker, B H, Palmer, C N A, 't Hart, L M, Giacomini, K M & Pearson, E R 2017, ' Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin : A MetGen Meta-Analysis ', Clinical Pharmacology & Therapeutics, vol. 101, no. 6, pp. 763-772 . https://doi.org/10.1002/cpt.567
Clinical pharmacology and therapeutics, vol 101, iss 6
Clinical Pharmacology & Therapeutics, 101(6), 763-772. Wiley-Blackwell
Clinical Pharmacology and Therapeutics, 101(6), 763-772. Wiley-Blackwell
Clinical Pharmacology and Therapeutics

Therapeutic response to metformin, a first-line drug for type 2 diabetes (T2D), is highly variable, in part likely due to genetic factors. To date, metformin pharmacogenetic studies have mainly focused on the impact of variants in metformin transport

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b762e525da754cb923dd8b91cd06ac1f
https://research.vumc.nl/en/publications/508fedaf-498a-4e2d-91a9-f7fedd97684b

The effect of alfacalcidiol and metformin on phenotype manifestations in women with polycystic ovary syndrome - a preliminary study

Autor: Ingrid Dravecká, Ivica Lazúrová, Jana Figurová, J Petrikova, M Vaľková, M Javorský

Publikováno v: Physiological research. 65(5)

Aim of this study was to evaluate the effect of vitamin D supplementation in obese, insulin resistant and vitamin D deficient PCOS women on biochemical and clinical hyperandrogenism and menstrual irregularity in comparison to effect of metformin or c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b1382dd94b035a22f5897752e9cc2e
https://pubmed.ncbi.nlm.nih.gov/27429113

Increased intracranial arterial resistance in patients with type 2 diabetes mellitus

Autor: I, Tkác, M, Troscák, M, Javorský, R, Petrík, M, Tomcová

Publikováno v: Wiener klinische Wochenschrift. 113(22)

The majority of the studies investigating risk factors for stroke have focused on the atherosclerosis of extracranial carotid arteries. Risk factors for the involvement of intracranial arteries in patients with stroke have not been widely investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71ac1ea233427f62bc74525e63f99543
https://pubmed.ncbi.nlm.nih.gov/11762124

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