Zobrazeno 1 - 10
of 45
pro vyhledávání: '"M Jack Borrok"'
Autor:
Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252060 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0234268.].
Externí odkaz:
https://doaj.org/article/51640645047d4adba46ece38f8fabcce
Autor:
Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234268 (2020)
Annexin A1 (anxA1) is an immunomodulatory protein that has been proposed as a tumor vascular target for antitumor biologic agents, yet to date the vascular expression of anxA1 in specific tumor indications has not been systematically assessed. Attemp
Externí odkaz:
https://doaj.org/article/0083d0c4b3bf4781a3221ea58fe585e7
Autor:
Yariv Mazor, Chunning Yang, M Jack Borrok, Joanne Ayriss, Karen Aherne, Herren Wu, William F Dall'Acqua
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157788 (2016)
Antibody-mediated immune effector functions play an essential role in the anti-tumor efficacy of many therapeutic mAbs. While much of the effort to improve effector potency has focused on augmenting the interaction between the antibody-Fc and activat
Externí odkaz:
https://doaj.org/article/85ce56ebbd954746be46444af03771f4
Autor:
Ian White, Ninkka Tamot, Rajitha Doddareddy, Jason Ho, Qun Jiao, Paul B. Harvilla, Tong-Yuan Yang, Brian Geist, M. Jack Borrok, Matthew D. Truppo, Rajkumar Ganesan, Partha Chowdhury, Adam Zwolak
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effecti
Externí odkaz:
https://doaj.org/article/a6460b31f1584b1b94ecaa2b69a6345e
Autor:
Sanjaya Singh, Rajkumar Ganesan, Iqbal S. Grewal, Sathya Venkataramani, Jun Chen, Christine Prokopowitz, Ninkka Tamot, Bharathikumar Vellalore Maruthachalam, Paul B. Harvilla, Yonghai Li, M. Jack Borrok
The success of chimeric antigen receptor (CAR) T-cell therapy against hematologic malignancies has altered the treatment paradigm for patients with these diseases. Nevertheless, the occurrence of relapse due to antigen escape or heterogeneous antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ebc4bb4bbad7141533cec8c0952379
https://doi.org/10.1158/2767-9764.c.6550719
https://doi.org/10.1158/2767-9764.c.6550719
Autor:
Gabriela M. Marchetti, Jennifer Cann, Keith W Rickert, Ruchi Gupta, Weiguang Zhao, Qing Li, Jonathan T. Boyd, Richard N. Hanna, Timothy Burwell, Herren Wu, M. Jack Borrok, William Dall'acqua, Joseph Grimsby, Emily L. Ongstad, Norman C. Peterson, Ping Tsui, Maureen Kennedy
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Communications Biology
Communications Biology
Systemic administration of bio-therapeutics can result in only a fraction of drug reaching targeted tissues, with the majority of drug being distributed to tissues irrelevant to the drug’s site of action. Targeted delivery to specific organs may al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32077e33fd53ad432f6d3fc3ce090745
http://link.springer.com/article/10.1038/s42003-019-0337-2
http://link.springer.com/article/10.1038/s42003-019-0337-2
Autor:
Paul B. Harvilla, Ninkka Tamot, Adam Zwolak, Jason Ho, Matthew D. Truppo, Rajitha Doddareddy, Tong-Yuan Yang, M. Jack Borrok, Ian White, Chowdhury Partha, Qun Jiao, Rajkumar Ganesan, Brian Geist
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The global health crisis and economic tolls of COVID-19 necessitate a panoply of strategies to treat SARS-CoV-2 infection. To date, few treatment options exist, although neutralizing antibodies against the spike glycoprotein have proven to be effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1068c0846939131cb4d5e3b77811623
https://doi.org/10.1080/19420862.2021.1987180
https://doi.org/10.1080/19420862.2021.1987180
Autor:
Qing Li, William Dall'acqua, Chingshen Chan, Richard N. Hanna, Norman C. Peterson, Alex Alfaro, José Luís Guedes dos Santos, Kevin L Allen, M. Jack Borrok, Herren Wu
Publikováno v:
ACS chemical biology. 15(4)
Efficacious use of therapeutic gene delivery via nanoparticles is hampered by the challenges associated with targeted delivery to tissues of interest. Systemic administration of lipid nanoparticle (LNP)-encapsulated mRNA leads to a protein expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518ad2e466339bcf890a8a4e07d5931c
https://pubmed.ncbi.nlm.nih.gov/32155049
https://pubmed.ncbi.nlm.nih.gov/32155049
Autor:
Sean Turman, Benjamin Kemp, Ronald Herbst, Janet Griffiths, Jennifer Cann, Mary Jane Hinrichs, M. Jack Borrok, Lisa Marie Kitching Vinall, D. Gareth Rees, David Howe, Yue Wang, Carlos Gonzalez, Shu Wang, Steven Eck, Hong Sun, Brian Naiman, Katherine A. Vousden, Koshu Okubo, Roland Kolbeck, Antonio DiGiandomenico, Tanya N. Mayadas, Gary P. Sims, Ethan Grant, Neang Ly, Ximing Xiong, Yebin Zhou, Srinath Kasturiangan, Holly Koelkebeck, Weiguang Zhao, Christopher Morehouse, Bo Chen
Publikováno v:
Annals of the Rheumatic Diseases
ObjectiveImmune complexes (ICs) play a critical role in the pathology of autoimmune diseases. The aim of this study was to generate and characterise a first-in-class anti-FcγRIIA antibody (Ab) VIB9600 (previously known as MEDI9600) that blocks IgG i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db10d8acb51c551c5223d6a8f518b5
http://europepmc.org/articles/PMC6352406
http://europepmc.org/articles/PMC6352406
Autor:
William Dall'acqua, Kevin L Allen, Keith W Rickert, Jason White, Kim Rosenthal, Ping Tsui, Norman C. Peterson, Qing Li, Chris Lloyd, Xizhe Gao, M. Jack Borrok, Herren Wu
Publikováno v:
Journal of Controlled Release. 279:126-135
The accumulation, dissemination and clearance of monoclonal antibody-based therapeutics or imaging reagents targeting tumor associated antigens is governed by several factors including affinity, size, charge, and valency. Tumor targeting antibody fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eeb1e87904ba1ce567ceb02a6d38b11
https://doi.org/10.1016/j.jconrel.2018.04.013
https://doi.org/10.1016/j.jconrel.2018.04.013